TTC9B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TTC9B_HUMAN
• UniProt AC: Q8N6N2
• Protein Name: Tetratricopeptide repeat protein 9B
• Gene Name: TTC9B
• Organism: Homo sapiens (Human).
• Sequence Length: 239
• Protein Sequence: MQRGALSPVLMLSAAPEPPPRPPPALSPPGSGPGSGSRHGSARPGPTPEPSGSLGAALDSSLRAAVAFKAEGQRCYREKKFREAIGKYHRALLQLKAAQGARPSGLPAPAPGPTSSPGPARLSEEQRRLVESTEVECYDSLTACLLQSELVNYERVREYCLKVLEKQQGNFKATYRAGIAFYHLGDYARALRYLQEARSREPTDTNVLRYIQLTQLKMNRCSLQREDSGAGSQTRDVIG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MQRGALSPVLMLSA -CCCCCCCCEEHHHC	16.66	24043423
13	Phosphorylation	LSPVLMLSAAPEPPP CCCEEHHHCCCCCCC	14.39	24043423
27	Phosphorylation	PRPPPALSPPGSGPG CCCCCCCCCCCCCCC	31.02	28111955
31	Phosphorylation	PALSPPGSGPGSGSR CCCCCCCCCCCCCCC	47.81	28111955
35	Phosphorylation	PPGSGPGSGSRHGSA CCCCCCCCCCCCCCC	36.41	28111955
37	Phosphorylation	GSGPGSGSRHGSARP CCCCCCCCCCCCCCC	23.85	28111955
41	Phosphorylation	GSGSRHGSARPGPTP CCCCCCCCCCCCCCC	18.25	28111955
47	Phosphorylation	GSARPGPTPEPSGSL CCCCCCCCCCCCCHH	46.31	28111955
51	Phosphorylation	PGPTPEPSGSLGAAL CCCCCCCCCHHHHHH	39.08	28111955
53	Phosphorylation	PTPEPSGSLGAALDS CCCCCCCHHHHHHCH	28.15	28111955
60	Phosphorylation	SLGAALDSSLRAAVA HHHHHHCHHHHHHHH	31.93	28111955
61	Phosphorylation	LGAALDSSLRAAVAF HHHHHCHHHHHHHHH	22.88	28111955
114	Phosphorylation	PAPAPGPTSSPGPAR CCCCCCCCCCCCCCC	47.99	27732954
115	Phosphorylation	APAPGPTSSPGPARL CCCCCCCCCCCCCCC	37.35	27732954
116	Phosphorylation	PAPGPTSSPGPARLS CCCCCCCCCCCCCCC	36.03	27732954
210	Phosphorylation	TDTNVLRYIQLTQLK CCCCHHHHHHHHHHH	6.72	25003641
214	Phosphorylation	VLRYIQLTQLKMNRC HHHHHHHHHHHHCCC	18.58	25003641
228	Phosphorylation	CSLQREDSGAGSQTR CCCCCCCCCCCCCCC	26.28	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TTC9B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TTC9B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TTC9B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PLCG1_HUMAN	PLCG1	physical	28514442
CLH2_HUMAN	CLTCL1	physical	28514442
LIPA1_HUMAN	PPFIA1	physical	28514442
HSP74_HUMAN	HSPA4	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.