dbPTM

TR13C_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TR13C_HUMAN
UniProt AC	Q96RJ3
Protein Name	Tumor necrosis factor receptor superfamily member 13C
Gene Name	TNFRSF13C
Organism	Homo sapiens (Human).
Sequence Length	184
Subcellular Localization	Membrane Single-pass type III membrane protein .
Protein Description	B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response..
Protein Sequence	MRRGPRSLRGRDAPAPTPCVPAECFDLLVRHCVACGLLRTPRPKPAGASSPAPRTALQPQESVGAGAGEAALPLPGLLFGAPALLGLALVLALVLVGLVSWRRRQRRLRGASSAEAPDGDKDAPEPLDKVIILSPGISDATAPAWPPPGEDPGTTPPGHSVPVPATELGSTELVTTKTAGPEQQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MRRGPRSLRGRDAP -CCCCCCCCCCCCCC	26.08	-
17	O-linked_Glycosylation	GRDAPAPTPCVPAEC CCCCCCCCCCCCHHH	31.27	OGP
40	Phosphorylation	VACGLLRTPRPKPAG HHHCCCCCCCCCCCC	24.50	28387310
49	Phosphorylation	RPKPAGASSPAPRTA CCCCCCCCCCCCCCC	35.62	28387310
50	Phosphorylation	PKPAGASSPAPRTAL CCCCCCCCCCCCCCC	25.25	30206219
112	Phosphorylation	QRRLRGASSAEAPDG HHHHCCCCCCCCCCC	32.67	26657352
113	Phosphorylation	RRLRGASSAEAPDGD HHHCCCCCCCCCCCC	29.60	30108239

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TR13C_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TR13C_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TR13C_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TRAF1_HUMAN	TRAF1	physical	19698991
TRAF3_HUMAN	TRAF3	physical	12471121
TRAF3_HUMAN	TRAF3	physical	15585864
TRAF2_HUMAN	TRAF2	physical	21041452
TRAF3_HUMAN	TRAF3	physical	21041452

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TR13C_HUMAN

Related Literatures of Post-Translational Modification