THAP2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: THAP2_HUMAN
• UniProt AC: Q9H0W7
• Protein Name: THAP domain-containing protein 2
• Gene Name: THAP2
• Organism: Homo sapiens (Human).
• Sequence Length: 228
• Protein Sequence: MPTNCAAAGCATTYNKHINISFHRFPLDPKRRKEWVRLVRRKNFVPGKHTFLCSKHFEASCFDLTGQTRRLKMDAVPTIFDFCTHIKSMKLKSRNLLKKNNSCSPAGPSNLKSNISSQQVLLEHSYAFRNPMEAKKRIIKLEKEIASLRRKMKTCLQKERRATRRWIKATCLVKNLEANSVLPKGTSEHMLPTALSSLPLEDFKILEQDQQDKTLLSLNLKQTKSTFI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
104	Phosphorylation	LKKNNSCSPAGPSNL HHHCCCCCCCCCCHH	20.01	22985185
143	Ubiquitination	KRIIKLEKEIASLRR HHHHHHHHHHHHHHH	65.93	2097226
158	Ubiquitination	KMKTCLQKERRATRR HHHHHHHHHHHHHHH	39.99	-
168	Sumoylation	RATRRWIKATCLVKN HHHHHHHHHHHHHCC	30.59	-
174	Sumoylation	IKATCLVKNLEANSV HHHHHHHCCCCCCCC	42.75	-
180	Phosphorylation	VKNLEANSVLPKGTS HCCCCCCCCCCCCCC	31.89	-
193	Phosphorylation	TSEHMLPTALSSLPL CCCCCCCCHHHCCCH	35.95	18452278
196	Phosphorylation	HMLPTALSSLPLEDF CCCCCHHHCCCHHHH	27.62	18452278
217	Phosphorylation	QQDKTLLSLNLKQTK HHCCCEEEEECCHHC	20.51	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of THAP2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of THAP2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of THAP2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
VANG1_HUMAN	VANGL1	physical	21988832
HCFC1_HUMAN	HCFC1	physical	26186194
HCFC2_HUMAN	HCFC2	physical	26186194
CTBL1_HUMAN	CTNNBL1	physical	26186194
LIN41_HUMAN	TRIM71	physical	26186194
DNJB8_HUMAN	DNAJB8	physical	26186194
CTBL1_HUMAN	CTNNBL1	physical	28514442
LIN41_HUMAN	TRIM71	physical	28514442
DNJB8_HUMAN	DNAJB8	physical	28514442
HCFC2_HUMAN	HCFC2	physical	28514442
OGT1_HUMAN	OGT	physical	28514442
HCFC1_HUMAN	HCFC1	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.