| UniProt ID | SYD_ARATH | |
|---|---|---|
| UniProt AC | F4IHS2 | |
| Protein Name | Chromatin structure-remodeling complex protein SYD | |
| Gene Name | SYD | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 3574 | |
| Subcellular Localization | Cytoplasm. Nucleus. | |
| Protein Description | Catalytic component of the chromatin structure-remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls stem cell fate via the transcription regulation of WUS in the shoot apical meristem, by modulating its promoter. LFY-dependent repressor of the meristem identity switch from vegetative to reproductive development probably by modulating chromatin state. Involved in the regulation of floral homeotic gene expression in response to environmental stimuli. Required for carpel and ovule development, and for cotyledon separation via the regulation of CUC2 transcription. Regulates the promoters of several genes downstream of the jasmonate (JA) and ethylene (ET) signaling pathways. Required for resistance against the necrotrophic pathogen B.cinerea but not the biotrophic pathogen P.syringae.. | |
| Protein Sequence | MTSSSHNIELEAAKFLHKLIQDSKDEPAKLATKLYVILQHMKTSGKENTMPYQVISRAMDTVVNQHGLDIEALKSSCLPHPGGTQTEDSGSAHLAGSSQAVGVSNEGKATLVENEMTKYDAFTSGRQLGGSNSASQTFYQGSGTQSNRSFDRESPSNLDSTSGISQPHNRSETMNQRDVKSSGKRKRGESSLSWDQNMDNSQIFDSHKIDDQTGEVSKIEMPGNSGDIRNLHVGLSSDAFTTPQCGWQSSEATAIRPAIHKEPGNNVAGEGFLPSGSPFREQQLKQLRAQCLVFLALRNGLVPKKLHVEIALRNTFREEDGFRGELFDPKGRTHTSSDLGGIPDVSALLSRTDNPTGRLDEMDFSSKETERSRLGEKSFANTVFSDGQKLLASRIPSSQAQTQVAVSHSQLTFSPGLTKNTPSEMVGWTGVIKTNDLSTSAVQLDEFHSSDEEEGNLQPSPKYTMSQKWIMGRQNKRLLVDRSWSLKQQKADQAIGSRFNELKESVSLSDDISAKTKSVIELKKLQLLNLQRRLRSEFVYNFFKPIATDVEHLKSYKKHKHGRRIKQLEKYEQKMKEERQRRIRERQKEFFGGLEVHKEKLEDLFKVRRERLKGFNRYAKEFHKRKERLHREKIDKIQREKINLLKINDVEGYLRMVQDAKSDRVKQLLKETEKYLQKLGSKLKEAKLLTSRFENEADETRTSNATDDETLIENEDESDQAKHYLESNEKYYLMAHSIKENINEQPSSLVGGKLREYQMNGLRWLVSLYNNHLNGILADEMGLGKTVQVISLICYLMETKNDRGPFLVVVPSSVLPGWQSEINFWAPSIHKIVYCGTPDERRKLFKEQIVHQKFNVLLTTYEYLMNKHDRPKLSKIHWHYIIIDEGHRIKNASCKLNADLKHYVSSHRLLLTGTPLQNNLEELWALLNFLLPNIFNSSEDFSQWFNKPFQSNGESSAEEALLSEEENLLIINRLHQVLRPFVLRRLKHKVENELPEKIERLIRCEASAYQKLLMKRVEDNLGSIGNAKSRAVHNSVMELRNICNHPYLSQLHSEEVNNIIPKHFLPPIVRLCGKLEMLDRMLPKLKATDHRVLFFSTMTRLLDVMEDYLTLKGYKYLRLDGQTSGGDRGALIDGFNKSGSPFFIFLLSIRAGGVGVNLQAADTVILFDTDWNPQVDLQAQARAHRIGQKKDVLVLRFETVNSVEEQVRASAEHKLGVANQSITAGFFDNNTSAEDRKEYLESLLRESKKEEDAPVLDDDALNDLIARRESEIDIFESIDKQRKENEMETWNTLVHGPGSDSFAHIPSIPSRLVTEDDLKLLYETMKLNDVPMVAKESTVGMKRKDGSMGGLDTHQYGRGKRAREVRSYEEKLTEEEFEKLCQTESPDSPQGKGEGSERSLANDTSNIPVENSSDTLLPTSPTQAITVQPMEPVRPQSHTLKEETQPIKRGRGRPKRTDKALTPVSLSAVSRTQATGNAISSAATGLDFVSSDKRLEAASHPTSSLALTSPDLSGPPGFQSLPASPAPTPIRGRGRGRSRGRGAGRGRRVEGVLHGSNSSITQRTETATSLASDAEATKFALPRSASEIVSRVPKANEGSTSNPDQVSPVHSATTALRSDKAADKDLDAPPGFDSGSHVQTLNVLENSSERKAFAVKKRPLIQGVSSQHPGPNKQPLDLPVSTSSTLLGGGPVQNQNAVSSVCDGSKSPSEGRTYTALQGVTTAPSDATLPMSSQPSDATLPMSSQPVGSTVEAQEANVPSLPAALPAKRRVRNLPSRGETPKRQGKRRGQPLPATDASSARSTGLTPQIEVKVGNLSGTKAKFDAVAKEQPHFSQSVAPDIHSSGSLSQEIRRDTSGTGGSARKQTADVTDVARVMKEIFSETSLLKHKVGEPSATTRTNVPDAQSPGEMNLHTVETHKAEDSSGLKNQEALYNLSKADKLVSDIPHPVPGDLTTSGSVANKDVDIGSSKVAAENELVKIPGGDVDSSVIQLSLGNTLTAKSSLEKCTADQLLGEKLSQEGETTPASDGETCHLAEETASSLSYVRSEPTASASTTAEPLPTDKLEKNISFQDEVKTLNGDKREAILLSSEEQTNVNSKIETNSEELQASRTDEVPHVDGKSVDVANQTVKEDEAKHSVEIQSSMLEPDELPNAGQKGHSSIDLQPLVLVTSNENAMSLDDKDYDPISKSADIEQDPEESVFVQGVGRPKVGTADTQMEDTNDAKLLVGCSVESEEKEKTLQSLIPGDDADTEQDPEESVSDQRPKVGSAYTQMEDTDEAKLLMGCSVESEEKEKTLQSHIPGDDADTEKNPEESVSVQGVDRPKVGTTDTQMEDTNDAKLLVGCSVASEEKEKTLQSHIPGDDADTEQNPEESVSVQGVNRPKVGNANTQMEDTDEAKVLVGCSVESEEKEKTLQSHIPGDDADTEQNPEESVSNFDRPKDGTADTHMEDIDDAKLLVGCSVESEEKEKSLQSHMPSDDAVLHAPFENTKDSKGDDLHGESLVSCPTMEVMEQKGFESETHARTDSGGIDRGNEVSENMSDGVKMNISSVQVPDASHDLNVSQDQTDIPLVGGIDPEHVQENVDVPASPHGAAPNIVIFQSEGHLSPSILPDDVAGQLESMSNDEKTNISSEQVPDVSHDLKVSQDQTDIPPVGGIVPENLQEIVDVPASPHGVVPDVVVSQSEEIQSPSILPDDVPGQPDDGNCEKMDTMQNNTSIDIGITSGKTCQPSSSTQPEDENRNSLSHCEPSEVVEQRDSRDQVCIGSVESQVEISSAILENRSADIQPPQSILVDQKDIEESKEPGIESADVSLHQLADIQAEPSNLVDQMDIEESKEPGTESADVSLHQLADIQPGPSILVDQMDTEKSKEPGTESADVSLHQLADIQPGPSILVDQMDTEKSKEPGTESADVSLHQLADIQPGPSILVDQMDTEEFKNPDVSLHQLADIEPSLSISAVQKNIEDKDQSHVETAGSELVDVSAECSTEPQVQLPPSSEPVGDMHVHLGASKSEIVAEGTDFSSSLPKTEEENAKSQLADTEPSSSLTAVQKNIEDQVETAGCEFVVVSTGCSTEPQVQLPPSAEPVVAEGTEFPSSLLMTGVDNSSHLMTGVDNAKTHLADVVPSSSPTTMEKNIEAQDQDQVTTGGCGLVDVLTECSSEPQLQLPPSAEPVISEGTELATLPLTEEENADSQLANIEPSSSPSVVEKNIEAQDQDQVKTAGCELVSTGCSSEPQVHLPPSAEPDGDIHVHLKETEKSESMVVVGEGTAFPSSLPVTEEGNAESQLADTEPFTSPTVVEKNIKDQEQVETTGCGLVDDSTGCSSEPQVQLPPSAEPMEGTHMHLEETKKSETVVTEIQLADIDPSFSLIVVQTNIEDQDQIETGGCDLINVPSGCSTEPQIQLSSSAEPEEGMHIHLEAAMNSETVVTEGSELPSSLPMTEDENADGQLAEVEPSVSLTVEQTNIEEKDHIETAECELVDVSPGCSSQPEVKFPPSPDAVGGMDVHLETVVTEDTDSNSSLPKTEEKDAENPSDRLDGESDGTTVATVEGTCVESNSLVAEESNIEVPKDNEDV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 131 | Phosphorylation | SGRQLGGSNSASQTF CCCCCCCCCCCCCCC | 30407730 | ||
| 133 | Phosphorylation | RQLGGSNSASQTFYQ CCCCCCCCCCCCCCC | 30407730 | ||
| 135 | Phosphorylation | LGGSNSASQTFYQGS CCCCCCCCCCCCCCC | 29654922 | ||
| 137 | Phosphorylation | GSNSASQTFYQGSGT CCCCCCCCCCCCCCC | 25561503 | ||
| 149 | Phosphorylation | SGTQSNRSFDRESPS CCCCCCCCCCCCCCC | 23776212 | ||
| 154 | Phosphorylation | NRSFDRESPSNLDST CCCCCCCCCCCCCCC | 23776212 | ||
| 156 | Phosphorylation | SFDRESPSNLDSTSG CCCCCCCCCCCCCCC | 23776212 | ||
| 160 | Phosphorylation | ESPSNLDSTSGISQP CCCCCCCCCCCCCCC | 23776212 | ||
| 161 | Phosphorylation | SPSNLDSTSGISQPH CCCCCCCCCCCCCCC | 19376835 | ||
| 162 | Phosphorylation | PSNLDSTSGISQPHN CCCCCCCCCCCCCCC | 19376835 | ||
| 165 | Phosphorylation | LDSTSGISQPHNRSE CCCCCCCCCCCCCCC | 19376835 | ||
| 434 | Phosphorylation | GWTGVIKTNDLSTSA CCCEEEECCCCCCCE | 23776212 | ||
| 438 | Phosphorylation | VIKTNDLSTSAVQLD EEECCCCCCCEEEHH | 23776212 | ||
| 439 | Phosphorylation | IKTNDLSTSAVQLDE EECCCCCCCEEEHHH | 23776212 | ||
| 440 | Phosphorylation | KTNDLSTSAVQLDEF ECCCCCCCEEEHHHC | 23776212 | ||
| 449 | Phosphorylation | VQLDEFHSSDEEEGN EEHHHCCCCCCCCCC | 23776212 | ||
| 450 | Phosphorylation | QLDEFHSSDEEEGNL EHHHCCCCCCCCCCC | 23776212 | ||
| 460 | Phosphorylation | EEGNLQPSPKYTMSQ CCCCCCCCCCCCCCC | 23776212 | ||
| 700 | Phosphorylation | FENEADETRTSNATD CCCCCCCCCCCCCCC | 30407730 | ||
| 702 | Phosphorylation | NEADETRTSNATDDE CCCCCCCCCCCCCCC | 30407730 | ||
| 703 | Phosphorylation | EADETRTSNATDDET CCCCCCCCCCCCCCC | 30407730 | ||
| 706 | Phosphorylation | ETRTSNATDDETLIE CCCCCCCCCCCCEEC | 30407730 | ||
| 1347 | Phosphorylation | GMKRKDGSMGGLDTH CCCCCCCCCCCCCHH | 25561503 | ||
| 1383 | Phosphorylation | EFEKLCQTESPDSPQ HHHHHHCCCCCCCCC | 23776212 | ||
| 1385 | Phosphorylation | EKLCQTESPDSPQGK HHHHCCCCCCCCCCC | 23776212 | ||
| 1388 | Phosphorylation | CQTESPDSPQGKGEG HCCCCCCCCCCCCCC | 30291188 | ||
| 1584 | Phosphorylation | TKFALPRSASEIVSR HCCCCCCCHHHHHHC | 25561503 | ||
| 1586 | Phosphorylation | FALPRSASEIVSRVP CCCCCCHHHHHHCCC | 30589143 | ||
| 1599 | Phosphorylation | VPKANEGSTSNPDQV CCCCCCCCCCCCCCC | 23776212 | ||
| 1600 | Phosphorylation | PKANEGSTSNPDQVS CCCCCCCCCCCCCCC | 23776212 | ||
| 1601 | Phosphorylation | KANEGSTSNPDQVSP CCCCCCCCCCCCCCC | 23776212 | ||
| 1607 | Phosphorylation | TSNPDQVSPVHSATT CCCCCCCCCCHHHHH | 30291188 | ||
| 1611 | Phosphorylation | DQVSPVHSATTALRS CCCCCCHHHHHHHHC | 23776212 | ||
| 1613 | Phosphorylation | VSPVHSATTALRSDK CCCCHHHHHHHHCCC | 23776212 | ||
| 1614 | Phosphorylation | SPVHSATTALRSDKA CCCHHHHHHHHCCCC | 23776212 | ||
| 1705 | Phosphorylation | VSSVCDGSKSPSEGR HHHCCCCCCCCCCCC | 27531888 | ||
| 1707 | Phosphorylation | SVCDGSKSPSEGRTY HCCCCCCCCCCCCCE | 29654922 | ||
| 1817 | Phosphorylation | EVKVGNLSGTKAKFD EEEECCCCCCHHHHC | 24894044 | ||
| 1819 | Phosphorylation | KVGNLSGTKAKFDAV EECCCCCCHHHHCHH | 24894044 | ||
| 1881 | Phosphorylation | RVMKEIFSETSLLKH HHHHHHHCHHCCHHC | 24894044 | ||
| 1899 | Phosphorylation | EPSATTRTNVPDAQS CCCCCCCCCCCCCCC | 23776212 | ||
| 1906 | Phosphorylation | TNVPDAQSPGEMNLH CCCCCCCCCCCCCCE | 30291188 | ||
| 1914 | Phosphorylation | PGEMNLHTVETHKAE CCCCCCEEEECCCCC | 23776212 | ||
| 2008 | Phosphorylation | KSSLEKCTADQLLGE CHHHHHCCHHHHHCH | 17317660 | ||
| 2018 | Phosphorylation | QLLGEKLSQEGETTP HHHCHHHHCCCCCCC | 23776212 | ||
| 2023 | Phosphorylation | KLSQEGETTPASDGE HHHCCCCCCCCCCCC | 23776212 | ||
| 2024 | Phosphorylation | LSQEGETTPASDGET HHCCCCCCCCCCCCC | 23776212 | ||
| 2027 | Phosphorylation | EGETTPASDGETCHL CCCCCCCCCCCCEEE | 23776212 | ||
| 2031 | Phosphorylation | TPASDGETCHLAEET CCCCCCCCEEECHHH | 23776212 | ||
| 2038 | Phosphorylation | TCHLAEETASSLSYV CEEECHHHHHHCHHC | 23776212 | ||
| 2070 | Phosphorylation | DKLEKNISFQDEVKT CCCCCCCCCHHHHHH | 19880383 | ||
| 2102 | Phosphorylation | NVNSKIETNSEELQA CCCHHCCCCHHHHHH | 19880383 | ||
| 2104 | Phosphorylation | NSKIETNSEELQASR CHHCCCCHHHHHHHC | 29654922 | ||
| 2315 | Phosphorylation | TEKNPEESVSVQGVD CCCCCCCCCEECCCC | 28011693 | ||
| 2317 | Phosphorylation | KNPEESVSVQGVDRP CCCCCCCEECCCCCC | 28011693 | ||
| 2374 | Phosphorylation | TEQNPEESVSVQGVN CCCCCCCCCCCCCCC | 28011693 | ||
| 2376 | Phosphorylation | QNPEESVSVQGVNRP CCCCCCCCCCCCCCC | 28011693 | ||
| 2525 | Phosphorylation | ESETHARTDSGGIDR CCCCCCCCCCCCCCC | 30407730 | ||
| 2527 | Phosphorylation | ETHARTDSGGIDRGN CCCCCCCCCCCCCCC | 30407730 | ||
| 2537 | Phosphorylation | IDRGNEVSENMSDGV CCCCCCCCCCCCCCC | 30407730 | ||
| 2711 | Phosphorylation | GNCEKMDTMQNNTSI CCCCCCCCCCCCCEE | 19880383 | ||
| 2716 | Phosphorylation | MDTMQNNTSIDIGIT CCCCCCCCEEEEEEC | 19880383 | ||
| 2717 | Phosphorylation | DTMQNNTSIDIGITS CCCCCCCEEEEEECC | 19880383 | ||
| 2731 | Phosphorylation | SGKTCQPSSSTQPED CCCCCCCCCCCCCCC | 23328941 | ||
| 2733 | Phosphorylation | KTCQPSSSTQPEDEN CCCCCCCCCCCCCCC | 23328941 | ||
| 3125 | Phosphorylation | HLADVVPSSSPTTME HHHHCCCCCCCCCHH | 23776212 | ||
| 3126 | Phosphorylation | LADVVPSSSPTTMEK HHHCCCCCCCCCHHH | 23776212 | ||
| 3127 | Phosphorylation | ADVVPSSSPTTMEKN HHCCCCCCCCCHHHC | 23776212 | ||
| 3129 | Phosphorylation | VVPSSSPTTMEKNIE CCCCCCCCCHHHCCC | 23776212 | ||
| 3130 | Phosphorylation | VPSSSPTTMEKNIEA CCCCCCCCHHHCCCC | 23776212 | ||
| 3482 | Phosphorylation | ECELVDVSPGCSSQP EEEEEECCCCCCCCC | 23776212 | ||
| 3486 | Phosphorylation | VDVSPGCSSQPEVKF EECCCCCCCCCCCCC | 23776212 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SYD_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SYD_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SYD_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| EF113_ARATH | Rap2.6L | physical | 23449474 | |
| TOE2_ARATH | TOE2 | physical | 23449474 | |
| BH085_ARATH | RSL2 | physical | 23449474 | |
| BH054_ARATH | RSL4 | physical | 23449474 | |
| KNAT3_ARATH | KNAT3 | physical | 23449474 | |
| NFYA5_ARATH | NF-YA5 | physical | 23449474 | |
| DMC1_ARATH | DMC1 | physical | 23449474 | |
| FAF1_ARATH | AT4G02810 | physical | 23449474 | |
| TCP3_ARATH | TCP3 | physical | 23449474 | |
| TCP22_ARATH | AT1G72010 | physical | 23449474 | |
| TCP13_ARATH | PTF1 | physical | 23449474 | |
| TCP16_ARATH | TCP16 | physical | 23449474 | |
| TCP19_ARATH | AT5G51910 | physical | 23449474 | |
| TCP5_ARATH | TCP5 | physical | 23449474 | |
| HMGB4_ARATH | HMGB4 | physical | 23449474 | |
| E2FA_ARATH | E2F3 | physical | 23449474 | |
| RAVL2_ARATH | AT1G50680 | physical | 23449474 | |
| RAVL3_ARATH | AT1G51120 | physical | 23449474 | |
| VAL1_ARATH | HSI2 | physical | 23449474 | |
| ARFC_ARATH | ETT | physical | 23449474 | |
| ARFR_ARATH | ARF18 | physical | 23449474 | |
| LBD40_ARATH | LBD40 | physical | 23449474 | |
| LBD35_ARATH | LBD35 | physical | 23449474 | |
| LFY_ARATH | LFY | physical | 22323601 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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