| UniProt ID | SUSD6_HUMAN | |
|---|---|---|
| UniProt AC | Q92537 | |
| Protein Name | Sushi domain-containing protein 6 {ECO:0000312|HGNC:HGNC:19956} | |
| Gene Name | SUSD6 {ECO:0000312|HGNC:HGNC:19956} | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 303 | |
| Subcellular Localization |
Membrane Single-pass type I membrane protein . |
|
| Protein Description | May play a role in growth-suppressive activity and cell death. [PubMed: 24652652 May be involved in the production of chemokine molecules in umbilical vein endothelial cells (HUVECs) cultured in THP1 monocyte LPS-induced medium] | |
| Protein Sequence | MCHGRIAPKSTSVFAVASVGHGVFLPLVILCTLLGDGLASVCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRLNEDKDTHTSLGVPTLSIVASTASSVALILLLVVLFVLLQPKLKSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCVPPADPRVQIVLSEGSGPSGRSVPREQQLPDQGACSSAGGEDEAPGQSGLCEAWGSRASETVMVHQATTSSWVAGSGNRQLAHKETADSENSDIQSLLSLTSEEYTDDIPLLKEA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 86 | Phosphorylation | MLKGDYKYLTCKNGE EECCEEEEEEECCCE | 30576142 | ||
| 88 | Phosphorylation | KGDYKYLTCKNGEWK CCEEEEEEECCCEEE | 30576142 | ||
| 101 | Phosphorylation | WKPAMEISCRLNEDK EEECEEEEEEECCCC | - | ||
| 257 | O-linked_Glycosylation | VMVHQATTSSWVAGS EEEEEEECCHHCCCC | OGP | ||
| 258 | Phosphorylation | MVHQATTSSWVAGSG EEEEEECCHHCCCCC | - | ||
| 259 | Phosphorylation | VHQATTSSWVAGSGN EEEEECCHHCCCCCC | - | ||
| 293 | Phosphorylation | LSLTSEEYTDDIPLL HHHCCCCCCCCCCHH | 25884760 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SUSD6_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SUSD6_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SUSD6_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ATL4_HUMAN | ADAMTSL4 | physical | 25416956 | |
| KR108_HUMAN | KRTAP10-8 | physical | 25416956 | |
| NED4L_HUMAN | NEDD4L | physical | 26186194 | |
| STXB4_HUMAN | STXBP4 | physical | 26186194 | |
| STXB4_HUMAN | STXBP4 | physical | 28514442 | |
| NED4L_HUMAN | NEDD4L | physical | 28514442 | |
| NEDD4_HUMAN | NEDD4 | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
