| UniProt ID | SOX_HUMAN | |
|---|---|---|
| UniProt AC | Q9P0Z9 | |
| Protein Name | Peroxisomal sarcosine oxidase | |
| Gene Name | PIPOX | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 390 | |
| Subcellular Localization | Peroxisome. | |
| Protein Description | Metabolizes sarcosine, L-pipecolic acid and L-proline.. | |
| Protein Sequence | MAAQKDLWDAIVIGAGIQGCFTAYHLAKHRKRILLLEQFFLPHSRGSSHGQSRIIRKAYLEDFYTRMMHECYQIWAQLEHEAGTQLHRQTGLLLLGMKENQELKTIQANLSRQRVEHQCLSSEELKQRFPNIRLPRGEVGLLDNSGGVIYAYKALRALQDAIRQLGGIVRDGEKVVEINPGLLVTVKTTSRSYQAKSLVITAGPWTNQLLRPLGIEMPLQTLRINVCYWREMVPGSYGVSQAFPCFLWLGLCPHHIYGLPTGEYPGLMKVSYHHGNHADPEERDCPTARTDIGDVQILSSFVRDHLPDLKPEPAVIESCMYTNTPDEQFILDRHPKYDNIVIGAGFSGHGFKLAPVVGKILYELSMKLTPSYDLAPFRISRFPSLGKAHL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 105 | Phosphorylation | KENQELKTIQANLSR CCCHHHHHHHHHHHH | 30.83 | 19845377 | |
| 111 | Phosphorylation | KTIQANLSRQRVEHQ HHHHHHHHHHHHHHH | 26.61 | 24275569 | |
| 126 | Acetylation | CLSSEELKQRFPNIR HCCHHHHHHHCCCCC | 42.58 | - | |
| 192 | Phosphorylation | TVKTTSRSYQAKSLV EEEECCCCEEECEEE | 22.74 | 24248375 | |
| 193 | Phosphorylation | VKTTSRSYQAKSLVI EEECCCCEEECEEEE | 16.04 | 24248375 | |
| 197 | Phosphorylation | SRSYQAKSLVITAGP CCCEEECEEEEEECH | 30.77 | 24248375 | |
| 206 | Phosphorylation | VITAGPWTNQLLRPL EEEECHHHHHHHHHH | 19.07 | 24248375 | |
| 221 | Phosphorylation | GIEMPLQTLRINVCY CCCCCCCEEEEEEEE | 26.20 | 24248375 | |
| 228 | Phosphorylation | TLRINVCYWREMVPG EEEEEEEEEHHCCCC | 11.83 | 24248375 | |
| 300 | Phosphorylation | GDVQILSSFVRDHLP HHHHHHHHHHHHHCC | 25.06 | 28857561 | |
| 318 | Phosphorylation | PEPAVIESCMYTNTP CCCEEEEECCCCCCC | 7.96 | 28258704 | |
| 319 | S-8alpha-FAD cysteine | EPAVIESCMYTNTPD CCEEEEECCCCCCCC | 1.24 | - | |
| 319 | Other | EPAVIESCMYTNTPD CCEEEEECCCCCCCC | 1.24 | - | |
| 321 | Phosphorylation | AVIESCMYTNTPDEQ EEEEECCCCCCCCHH | 10.93 | 28258704 | |
| 322 | Phosphorylation | VIESCMYTNTPDEQF EEEECCCCCCCCHHH | 13.01 | 28258704 | |
| 324 | Phosphorylation | ESCMYTNTPDEQFIL EECCCCCCCCHHHCC | 25.07 | 28258704 | |
| 380 | Phosphorylation | DLAPFRISRFPSLGK CCCCCEEECCCCCCC | 24.50 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SOX_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SOX_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SOX_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ELP6_HUMAN | ELP6 | physical | 26186194 | |
| FKBP5_HUMAN | FKBP5 | physical | 26186194 | |
| SNAG_HUMAN | NAPG | physical | 26186194 | |
| ELP4_HUMAN | ELP4 | physical | 26186194 | |
| ZN217_HUMAN | ZNF217 | physical | 26186194 | |
| ELP5_HUMAN | ELP5 | physical | 26186194 | |
| ELP4_HUMAN | ELP4 | physical | 28514442 | |
| ELP5_HUMAN | ELP5 | physical | 28514442 | |
| ZN217_HUMAN | ZNF217 | physical | 28514442 | |
| ELP6_HUMAN | ELP6 | physical | 28514442 | |
| SNAG_HUMAN | NAPG | physical | 28514442 | |
| FKBP5_HUMAN | FKBP5 | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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