SNP25_DROME - dbPTM
SNP25_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SNP25_DROME
UniProt AC P36975
Protein Name Synaptosomal-associated protein 25
Gene Name Snap25
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 212
Subcellular Localization Cell junction, synapse, synaptosome. Complexed with macromolecular elements of the nerve terminal..
Protein Description May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion (By similarity)..
Protein Sequence MPADPSEEVAPQVPKTELEELQINAQGVADESLESTRRMLALCEESKEAGIRTLVALDDQGEQLDRIEEGMDQINADMREAEKNLSGMEKCCGICVLPCNKSQSFKEDDGTWKGNDDGKVVNNQPQRVMDDRNGMMAQAGYIGRITNDAREDEMEENMGQVNTMIGNLRNMALDMGSELENQNRQIDRINRKGESNEARIAVANQRAHQLLK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
6Phosphorylation--MPADPSEEVAPQV
--CCCCCCCCCCCCC
47.1127794539
35PhosphorylationVADESLESTRRMLAL
CCCHHHHHHHHHHHH
32.2922817900
86PhosphorylationREAEKNLSGMEKCCG
HHHHHHHCHHHHHCE
45.5527626673
106UbiquitinationCNKSQSFKEDDGTWK
CCCCCCCCCCCCCCC
66.5331113955

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SNP25_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SNP25_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SNP25_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
STX1A_DROMESyx1Aphysical
22036573
SLY1_DROMESlhphysical
22036573
STX5_DROMESyx5physical
22036573
SNAP_DROMEalphaSnapphysical
22036573
GOSR2_DROMEMembrinphysical
22036573
NSF2_DROMENsf2physical
22036573

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SNP25_DROME

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Related Literatures of Post-Translational Modification

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