| UniProt ID | SGCB_MOUSE | |
|---|---|---|
| UniProt AC | P82349 | |
| Protein Name | Beta-sarcoglycan | |
| Gene Name | Sgcb | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 320 | |
| Subcellular Localization |
Cell membrane, sarcolemma Single-pass type II membrane protein . Cytoplasm, cytoskeleton . |
|
| Protein Description | Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.. | |
| Protein Sequence | MAAAAAAAAATEQQGSNGPVKKSMREKAVERRNVNKEHNSNFKAGYIPIDEDRLHKTGLRGRKGNLAICVIVLLFILAVINLLITLVIWAVIRIGPNGCDSMEFHESGLLRFKQVSDMGVIHPLYKSTVGGRRNENLVITGNNQPIVFQQGTTKLSVEKNKTSITSDIGMQFFDPRTHNILFSTDYETHEFHLPSGVKSLNVQKASTERITSNATSDLNIKVDGRAIVRGNEGVFIMGKTIEFHMGGDVELKAENSIILNGTVMVSPTRLPSSSSGDQSGSGDWVRYKLCMCADGTLFKVQVTGHNMGCQVSDNPCGNTH | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 16 | Phosphorylation | AATEQQGSNGPVKKS HHHHHCCCCCCCCHH | 33.99 | 23684622 | |
| 21 | Ubiquitination | QGSNGPVKKSMREKA CCCCCCCCHHHHHHH | 42.11 | - | |
| 43 | Ubiquitination | KEHNSNFKAGYIPID HHHCCCCCCEEEECC | 45.19 | - | |
| 46 | Phosphorylation | NSNFKAGYIPIDEDR CCCCCCEEEECCHHH | 14.37 | 29514104 | |
| 56 | Ubiquitination | IDEDRLHKTGLRGRK CCHHHHHHCCCCCCC | 49.21 | - | |
| 116 | Phosphorylation | LLRFKQVSDMGVIHP CEEEEEECCCCCEEE | 21.27 | 26643407 | |
| 160 | N-linked_Glycosylation | TKLSVEKNKTSITSD EEEEEECCCCCCCCC | 39.05 | - | |
| 213 | N-linked_Glycosylation | STERITSNATSDLNI CCCEECCCCCCCCEE | 38.29 | - | |
| 260 | N-linked_Glycosylation | AENSIILNGTVMVSP EECEEEECCEEEECC | 33.41 | - | |
| 273 | Phosphorylation | SPTRLPSSSSGDQSG CCCCCCCCCCCCCCC | 26.95 | 22871156 | |
| 279 | Phosphorylation | SSSSGDQSGSGDWVR CCCCCCCCCCCCEEE | 39.40 | 30165576 | |
| 287 | Phosphorylation | GSGDWVRYKLCMCAD CCCCEEEEEEEEECC | 9.93 | 22871156 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SGCB_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SGCB_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SGCB_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SGCA_MOUSE | Sgca | physical | 9864373 | |
| SGCG_MOUSE | Sgcg | physical | 9864373 | |
| SGCD_MOUSE | Sgcd | physical | 9864373 | |
| SGCG_MOUSE | Sgcg | physical | 12189167 | |
| SGCD_MOUSE | Sgcd | physical | 12189167 | |
| SGCZ_MOUSE | Sgcz | physical | 12189167 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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