SGCG_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SGCG_MOUSE
• UniProt AC: P82348
• Protein Name: Gamma-sarcoglycan
• Gene Name: Sgcg
• Organism: Mus musculus (Mouse).
• Sequence Length: 291
• Subcellular Localization: Cell membrane, sarcolemma ; Single-pass type II membrane protein . Cytoplasm, cytoskeleton .
• Protein Description: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix..
• Protein Sequence: MVREQYTTVTEGTHIERPENQHIYKIGIYGWRKRCLYLFVLLLLAILVVNLALTIWILKVMWFSPIGMGHLHVTADGLRLEGESEFLFPLYAKEIRSRVDSSLLLQSTQNVTVSARNSEGEVTGRVKVGAQMVEVQSQHFQINSEDGKPLFSAEEQDVVVGTGRLRVTGPEGALFEHSVETPLVRADPFQDLRLESPTRSLSMDAPRGVHVKANAGKLEALSQMDIILQSSEGVLVLDAETVGLTKLKQGTQGPAGSSNGFYEICACPDGKLYLSMAGEVTTCEEHSHVCL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MVREQYTTVTEGT --CCCCEEEEECCCC	10.30	28576409
93	Ubiquitination	FLFPLYAKEIRSRVD EEHHHHHHHHHHHCC	39.87	22790023
110	N-linked_Glycosylation	LLLQSTQNVTVSARN HEEEEEECEEEEEEC	31.36	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SGCG_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SGCG_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SGCG_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SGCG_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.