dbPTM

SET10_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SET10_SCHPO
UniProt AC	O74738
Protein Name	Ribosomal lysine N-methyltransferase set10
Gene Name	set10
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	547
Subcellular Localization	Cytoplasm . Nucleus .
Protein Description	S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates ribosomal protein L23 (rpl23a and rpl23b)..
Protein Sequence	MEKLLHEALQNGCKLHKSVEFIQSRDDNACFGSYIAVAQNDIAPDQLLISCPFEYAITYNKAKEELKKLNPNFESCNPHITLCTFLALESLKGIQSKWYGYIEYLPKTFNTPLYFNENDNAFLISTNAYSAAQERLHIWKHEYQEALSLHPSPTERFTFDLYIWSATVFSSRCFSSNLIYKDSESTPILLPLIDSLNHKPKQPILWNSDFQDEKSVQLISQELVAKGNQLFNNYGPKGNEELLMGYGFCLPDNPFDTVTLKVAIHPDLPHKDQKAAILENDCQFQLSNLVFFLPKSPDKEIFQKILQCLAVVTASSLELRKLTAHLLTGDLASYVPSLRGQIKSLEVLLMYIDSRADLLLKSNPQVSPTSERQVWAKIYRDSQINILQDSITYVKNYMEESLQKTYKPLPNLLQYLILNSISIFLLQHPLFAPLSHAIESLYGSTDAEALVATDEQDILMILICVYCLSISEKLPFSISMLVEGYPAVANPEGVEVFEILDEMFFQQFTNVFGESKHFNKENVSWALQLVNDESLDFSGFTFIIAHN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of SET10_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SET10_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SET10_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SET10_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YOI5_SCHPO	SPBC1778.05c	genetic	22681890
RICTR_SCHPO	ste20	genetic	22681890
SSN3_SCHPO	srb10	genetic	22681890
YO48_SCHPO	SPBC36B7.08c	genetic	22681890
SEC14_SCHPO	spo20	genetic	22681890
SUM2_SCHPO	sum2	genetic	22681890
MCM7_SCHPO	mcm7	physical	26771498
SOL1_SCHPO	sol1	physical	26771498
GRPE_SCHPO	mge1	physical	26771498
TAS3_SCHPO	tas3	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SET10_SCHPO

Related Literatures of Post-Translational Modification