| UniProt ID | SDC_DROME | |
|---|---|---|
| UniProt AC | P49415 | |
| Protein Name | Syndecan | |
| Gene Name | Sdc | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 399 | |
| Subcellular Localization |
Membrane Single-pass type I membrane protein. |
|
| Protein Description | Cell surface proteoglycan that bears heparan sulfate. Required for axonal and myotube guidance, is a necessary component of slit/robo signaling and is required in the slit target cells.. | |
| Protein Sequence | MKPKQKISVEPLLLVAILIGVLVAATHAQDQKSVKPSAAAPSAAASRPHDEIYIDDDSIEGSGGRGGIHEDLEKDPDYSGSGFGPDDEDAEPDQHSHSSHNTRISQSSNSGINTAHTPTQTSSTIPTTSTSTPMPTTTPTATTPASTTTAAATQISSFANSSSTTTTTLAPTIPAEPQQPLFPPFDKDLDTESSGDGIDADAEDDDEDDGDDKDYDYNKELDKEIDIDGPEPGHLPPVVHHNTVETGHIPTTDEIDVDGGDEDDNGDSDIDGPRIGGNDGDITERGPGAGGSNVHELDPNTNVNSQPSDTKGIDHRPNGNEVVIMSEDDRTSSFFSQPGILAAVIGGAVVGLLCAILVVMFIVYRMRKKDEGSYALDEPKRSPANNSYAKNANNREFYA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 62 | O-linked_Glycosylation | DDDSIEGSGGRGGIH CCCCCCCCCCCCCCC | 25.86 | - | |
| 79 | O-linked_Glycosylation | LEKDPDYSGSGFGPD HHHCCCCCCCCCCCC | 33.59 | - | |
| 81 | O-linked_Glycosylation | KDPDYSGSGFGPDDE HCCCCCCCCCCCCCC | 25.63 | - | |
| 110 | O-linked_Glycosylation | RISQSSNSGINTAHT CCCCCCCCCCCCCCC | 42.89 | - | |
| 160 | N-linked_Glycosylation | TQISSFANSSSTTTT HHHHHHCCCCCCCEE | 40.18 | - | |
| 194 | O-linked_Glycosylation | KDLDTESSGDGIDAD CCCCCCCCCCCCCCC | 34.37 | - | |
| 382 | Phosphorylation | ALDEPKRSPANNSYA CCCCCCCCCCCCCCC | 34.19 | 25749252 | |
| 388 | Phosphorylation | RSPANNSYAKNANNR CCCCCCCCCCCCCCC | 24.58 | 25749252 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SDC_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SDC_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SDC_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MED31_DROME | MED31 | physical | 14605208 | |
| LAR_DROME | Lar | genetic | 16213816 | |
| EXT1_DROME | ttv | genetic | 19574454 | |
| SLIT_DROME | sli | genetic | 14761655 | |
| SLIT_DROME | sli | genetic | 21836636 | |
| LAR_DROME | Lar | physical | 16213816 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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