S38A7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: S38A7_HUMAN
• UniProt AC: Q9NVC3
• Protein Name: Putative sodium-coupled neutral amino acid transporter 7
• Gene Name: SLC38A7
• Organism: Homo sapiens (Human).
• Sequence Length: 462
• Subcellular Localization: Membrane; Multi-pass membrane protein. In neurons, located in soma and axons..
• Protein Description: Mediates sodium-dependent transport of amino acids, preferentially L-glutamine..
• Protein Sequence: MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVWAVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTISLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPASWMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFVFPGLCLIQAKLSEMEEVKPASWWVLVSYGVLLVTLGAFIFGQTTANAIFVDLLA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MAQVSINNDYSE ---CCCEEECCCCCC	13.91	21955146
10	Phosphorylation	QVSINNDYSEWDLST CEEECCCCCCCCCCC	15.60	20068231
11	Phosphorylation	VSINNDYSEWDLSTD EEECCCCCCCCCCCC	34.77	21955146
16	Phosphorylation	DYSEWDLSTDAGERA CCCCCCCCCCHHHHH	23.05	20068231
17	Phosphorylation	YSEWDLSTDAGERAR CCCCCCCCCHHHHHH	36.85	25159151
28	Phosphorylation	ERARLLQSPCVDTAP HHHHHHCCCCCCCCC	21.89	30266825
33	Phosphorylation	LQSPCVDTAPKSEWE HCCCCCCCCCHHHCC	25.18	30266825
36	Ubiquitination	PCVDTAPKSEWEASP CCCCCCCHHHCCCCC	59.55	-
37	O-linked_Glycosylation	CVDTAPKSEWEASPG CCCCCCHHHCCCCCC	47.05	OGP
42	O-linked_Glycosylation	PKSEWEASPGGLDRG CHHHCCCCCCCCCCC	16.74	OGP
192	Phosphorylation	FLFILPLSIPREIGF HHHHHCCCCCHHHCH	28.71	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of S38A7_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of S38A7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of S38A7_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TCEA1_HUMAN	TCEA1	physical	28514442
GGA1_HUMAN	GGA1	physical	28514442
EF1A2_HUMAN	EEF1A2	physical	28514442
ERF1_HUMAN	ETF1	physical	28514442
VRK1_HUMAN	VRK1	physical	28514442
ACL6B_HUMAN	ACTL6B	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.