dbPTM

RKM4_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RKM4_SCHPO
UniProt AC	Q9P6L2
Protein Name	Ribosomal lysine N-methyltransferase 4 {ECO:0000250\|UniProtKB:Q12504}
Gene Name	set13 {ECO:0000303\|PubMed:20444689}
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	468
Subcellular Localization	Nucleus .
Protein Description	S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L42 (rpl42) at 'Lys-55'..
Protein Sequence	MLKQAESMLKWAIEKDNYTTSEKIGLNDYRHVHESLGIGFIALEDIKEDEKLVSFKKDSVLCLTNSDLAQLPEVQSLPSWAALLLVMATENASPNSFWRPYLSIFPTKERITSPFYWDENKKDALLRGTVLESNEDCNEITQLWIDRIEPIIKLYPNRFSQVSYEDFLRMSAVMLAYSFDIEKTKSPISNENEKSAAETSIKEDKNGDAAKKNEGSANQDDEKLHSQSLVGNNCEVNSEDEFSDLESEVDPDELEKAMCPISDMFNGDDELCNIRLYDINGTLTMIATRDIKKGEQLWNTYGELDNSELFRKYGFTKKKGTPHDFVLIKKEHWLPEYIEKLGFEEVEARLELLCREELLYNLEGDFTFSKADLTFKEICLAFVLMEKEKELISVPSKSDIKPKHYRKLLKIIEKRINMYPKISDPKNFDEENAKTLIEGEIDILQNLSAKVKEALTKNRPKKKQKVDH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
200	Phosphorylation	EKSAAETSIKEDKNG HHHHHHHHHHHCCCC	24.14	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RKM4_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RKM4_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RKM4_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RL44_SCHPO	rpl42	physical	20444689
YBPD_SCHPO	SPBC16H5.13	genetic	18818364
PEF1_SCHPO	pef1	genetic	18818364
RAF1_SCHPO	raf1	genetic	18818364
FIN1_SCHPO	fin1	genetic	22681890
YEEB_SCHPO	SPAC19A8.11c	genetic	22681890
PPK9_SCHPO	ppk9	genetic	22681890

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RKM4_SCHPO

Related Literatures of Post-Translational Modification