RL44_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RL44_SCHPO
• UniProt AC: Q9UTI8
• Protein Name: 60S ribosomal protein L42
• Gene Name: rpl42
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 106
• Subcellular Localization: Cytoplasm .
• Protein Sequence: MVNIPKTRKTYCPGKNCRKHTVHRVTQYKKGPDSKLAQGKRRYDRKQSGFGGQTKPVFHKKAKVTKKVVLRLECVSCKYKNQLVLKRCKHFELGGEKKTKGAAIQF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
21	Phosphorylation	GKNCRKHTVHRVTQY CCCCCCCCCHHHCCC	22.50	24763107
55	Methylation	SGFGGQTKPVFHKKA CCCCCCCCCCCCCCC	31.15	20444689
79	Phosphorylation	LECVSCKYKNQLVLK EEEEECCCCCCCHHE	21.35	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RL44_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RL44_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RL44_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GCN2_SCHPO	gcn2	genetic	20444689
YGNB_SCHPO	nap2	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Methylation

"Methylation of ribosomal protein L42 regulates ribosomal function andstress-adapted cell growth.";
Shirai A., Sadaie M., Shinmyozu K., Nakayama J.;
J. Biol. Chem. 285:22448-22460(2010).
Cited for: METHYLATION AT LYS-55, AND MASS SPECTROMETRY.
PubMed: 20444689