RDGC_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RDGC_DROME
• UniProt AC: P40421
• Protein Name: Serine/threonine-protein phosphatase rdgC
• Gene Name: rdgC
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 661
• Protein Description: Phosphatase required to prevent light-induced retinal degeneration..
• Protein Sequence: MDENAIRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIKHMPQAAGRKNQYQGSAHVSVLDDKDDLVEEFGDIVNAKIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDSTSLDLIKSIDRGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFVQYISAASQTKRLSFKQRMGIVESSALKELAVRMRDHRDELEDEFRKYDPKDSGYISISHWCKVMENVTKLGLPWRLLRDKLAPGTDSQKVNYNRTLDLLDTDVILEAEADGMSVMDALYANKASLVAIFNIIDADNSGEITLDEFETAIDLLVAHMPGAYSKAEMLEKCRMMDLNGDGKVDLNEFLEAFRLSDLHRKEQQDENIRRRSTGRPSVAKTATDPVTLLADKISKNTLVVEHDIDPTDCESKVIDPKKS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
419	Phosphorylation	ASQTKRLSFKQRMGI HHHHCCCCHHHHHCC	34.14	22668510
475	Ubiquitination	KVMENVTKLGLPWRL HHHHHHHHCCCCHHH	35.95	31113955
491	Ubiquitination	RDKLAPGTDSQKVNY HHCCCCCCCCCCCCC	31.27	31113955
560	Ubiquitination	TAIDLLVAHMPGAYS HHHHHHHHHCCCCCC	8.01	31113955

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RDGC_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RDGC_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RDGC_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CALM_DROME	Cam	physical	11754840
OPS1_DROME	ninaE	genetic	7695903
OPS1_DROME	ninaE	genetic	9235891
DYN_DROME	shi	genetic	11086990

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.