RBL15_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RBL15_ARATH
• UniProt AC: Q8LB17
• Protein Name: Rhomboid-like protein 15 {ECO:0000303|PubMed:17181860}
• Gene Name: RBL15 {ECO:0000303|PubMed:17181860}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 403
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Description: Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis. May function in senescence..
• Protein Sequence: MRPNIVTEAGVQTRVGQWWNAIPFLTSSVVVVCGVIYLICLLTGYDTFYEVCFLPSAIISRFQVYRFYTAIIFHGSLLHVLFNMMALVPMGSELERIMGSVRLLYLTVLLATTNAVLHLLIASLAGYNPFYQYDHLMNECAIGFSGILFSMIVIETSLSGVTSRSVFGLFNVPAKLYPWILLIVFQLLMTNVSLLGHLCGILSGFSYSYGLFNFLMPGSSFFTTIESASWMSSFIRRPKFIMCTGGNPSSYIPTYSAQNTTSSGFSTGNAWRSLSSWLPQREASNQSSEDSRFPGRGRTLSTARDPTAPAGETDPNLHARLLEDSSSPDRLSDATVNTVADSRQAPIANAAVLPQSQGRVAASEEQIQKLVAMGFDRTQVEVALAAADDDLTVAVEILMSQQA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
273	Phosphorylation	STGNAWRSLSSWLPQ CCCHHHHHHHHHCCH		25561503
275	Phosphorylation	GNAWRSLSSWLPQRE CHHHHHHHHHCCHHH		30291188
276	Phosphorylation	NAWRSLSSWLPQREA HHHHHHHHHCCHHHH		29654922
287	Phosphorylation	QREASNQSSEDSRFP HHHHCCCCCCCCCCC		25561503
288	Phosphorylation	REASNQSSEDSRFPG HHHCCCCCCCCCCCC		25561503
291	Phosphorylation	SNQSSEDSRFPGRGR CCCCCCCCCCCCCCC		29654922
299	Phosphorylation	RFPGRGRTLSTARDP CCCCCCCCCCCCCCC		23111157
301	Phosphorylation	PGRGRTLSTARDPTA CCCCCCCCCCCCCCC		24601666
302	Phosphorylation	GRGRTLSTARDPTAP CCCCCCCCCCCCCCC		23111157
307	Phosphorylation	LSTARDPTAPAGETD CCCCCCCCCCCCCCC		19376835
313	Phosphorylation	PTAPAGETDPNLHAR CCCCCCCCCCCHHHH		19376835
325	Phosphorylation	HARLLEDSSSPDRLS HHHHHCCCCCCCHHC		23776212
326	Phosphorylation	ARLLEDSSSPDRLSD HHHHCCCCCCCHHCC		23776212
327	Phosphorylation	RLLEDSSSPDRLSDA HHHCCCCCCCHHCCC		23776212
332	Phosphorylation	SSSPDRLSDATVNTV CCCCCHHCCCCHHHH		30291188
335	Phosphorylation	PDRLSDATVNTVADS CCHHCCCCHHHHCHH		23776212
338	Phosphorylation	LSDATVNTVADSRQA HCCCCHHHHCHHCCC		23776212
342	Phosphorylation	TVNTVADSRQAPIAN CHHHHCHHCCCCCCC		19376835

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RBL15_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RBL15_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RBL15_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RMA1_ARATH	RMA1	physical	21798944
RTNLD_ARATH	BTI3	physical	21798944
VAP11_ARATH	VAP	physical	21798944

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.