| UniProt ID | RB33B_MOUSE | |
|---|---|---|
| UniProt AC | O35963 | |
| Protein Name | Ras-related protein Rab-33B | |
| Gene Name | Rab33b | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 229 | |
| Subcellular Localization |
Golgi apparatus membrane Lipid-anchor . Golgi apparatus, cis-Golgi network . Under starvation conditions punctate RAB33B-positive structures are often observed in the cytoplasm (PubMed:18448665). |
|
| Protein Description | Protein transport. Acts, in coordination with RAB6A, to regulate intra-Golgi retrograde trafficking (By similarity). It is involved in autophagy, acting as a modulator of autophagosome formation.. | |
| Protein Sequence | MTSEMESSLEVSFSSSCAVSGASGCLPPARSRIFKIIVIGDSNVGKTCLTYRFCAGRFPDRTEATIGVDFRERAVDIDGERIKIQLWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTNMASFHSLPAWIEECKQHLLANDIPRILVGNKCDLRSAIQVPTDLAQKFADTHSMPLFETSAKNPNDNDHVEAIFMTLAHKLKSHKPLMLSQLPDNRISLKPETKPAVTCWC | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 83 | Malonylation | DIDGERIKIQLWDTA ECCCCEEEEEEECCC | 30.53 | 26073543 | |
| 98 | Phosphorylation | GQERFRKSMVQHYYR CHHHHHHHHHHHHHH | 21.67 | 29472430 | |
| 103 | Phosphorylation | RKSMVQHYYRNVHAV HHHHHHHHHHHCCEE | 6.24 | 29514104 | |
| 149 | Ubiquitination | PRILVGNKCDLRSAI CCEEECCCCCHHHHC | 24.17 | - | |
| 227 | Geranylgeranylation | ETKPAVTCWC----- CCCCCEEECC----- | 2.54 | - | |
| 229 | Methylation | KPAVTCWC------- CCCEEECC------- | 4.32 | - | |
| 229 | Geranylgeranylation | KPAVTCWC------- CCCEEECC------- | 4.32 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RB33B_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RB33B_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RB33B_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| A16L1_MOUSE | Atg16l1 | physical | 18448665 | |
| ATG12_MOUSE | Atg12 | physical | 18448665 | |
| ATG5_MOUSE | Atg5 | physical | 18448665 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
