| UniProt ID | RASM_HUMAN | |
|---|---|---|
| UniProt AC | O14807 | |
| Protein Name | Ras-related protein M-Ras | |
| Gene Name | MRAS | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 208 | |
| Subcellular Localization |
Cell membrane Lipid-anchor Cytoplasmic side . |
|
| Protein Description | May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway.. | |
| Protein Sequence | MATSAVPSDNLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIRQQIPEKSQKKKKKTKWRGDRATGTHKLQCVIL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MATSAVPSDN -----CCCCCCCCCC | 18.87 | 24043423 | |
| 4 | Phosphorylation | ----MATSAVPSDNL ----CCCCCCCCCCC | 20.10 | 24043423 | |
| 8 | Phosphorylation | MATSAVPSDNLPTYK CCCCCCCCCCCCCEE | 32.31 | 24043423 | |
| 13 | Phosphorylation | VPSDNLPTYKLVVVG CCCCCCCCEEEEEEC | 36.13 | 25690035 | |
| 14 | Phosphorylation | PSDNLPTYKLVVVGD CCCCCCCEEEEEECC | 10.61 | 25690035 | |
| 84 | Phosphorylation | MREQYMRTGDGFLIV HHHHHHHHCCCEEEE | 24.08 | - | |
| 146 | Phosphorylation | EQGKEMATKHNIPYI HHHHHHHHHCCCCEE | 31.37 | 27251275 | |
| 152 | Phosphorylation | ATKHNIPYIETSAKD HHHCCCCEEECCCCC | 13.95 | 27251275 | |
| 155 | Phosphorylation | HNIPYIETSAKDPPL CCCCEEECCCCCCCC | 25.15 | 28348404 | |
| 156 | Phosphorylation | NIPYIETSAKDPPLN CCCEEECCCCCCCCC | 22.11 | 28348404 | |
| 205 | Methylation | TGTHKLQCVIL---- CCCEEEEEEEC---- | 2.73 | - | |
| 205 | Geranylgeranylation | TGTHKLQCVIL---- CCCEEEEEEEC---- | 2.73 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RASM_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RASM_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RASM_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| GNDS_HUMAN | RALGDS | physical | 9400994 | |
| BRAF_HUMAN | BRAF | physical | 12138204 | |
| RPGF5_HUMAN | RAPGEF5 | physical | 10934204 | |
| ELOC_HUMAN | TCEB1 | physical | 21988832 | |
| SHOC2_HUMAN | SHOC2 | physical | 25022756 | |
| HUWE1_HUMAN | HUWE1 | physical | 25022756 | |
| RAF1_HUMAN | RAF1 | physical | 25022756 | |
| SHOC2_HUMAN | SHOC2 | physical | 26519477 | |
| KPYR_HUMAN | PKLR | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
