UniProt ID | RASD1_HUMAN | |
---|---|---|
UniProt AC | Q9Y272 | |
Protein Name | Dexamethasone-induced Ras-related protein 1 | |
Gene Name | RASD1 | |
Organism | Homo sapiens (Human). | |
Sequence Length | 281 | |
Subcellular Localization |
Cell membrane Lipid-anchor Cytoplasmic side . Cytoplasm, perinuclear region. Nucleus. |
|
Protein Description | Small GTPase. Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65 (By similarity).. | |
Protein Sequence | MKLAAMIKKMCPSDSELSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLRQQILDTKSCLKNKTKENVDVPLVICGNKGDRDFYREVDQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRALFAMAKLPSEMSPDLHRKVSVQYCDVLHKKALRNKKLLRAGSGGGGGDPGDAFGIVAPFARRPSVHSDLMYIREKASAGSQAKDKERCVIS | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
11 | S-nitrosylation | AAMIKKMCPSDSELS HHHHHHHCCCCCCCC | 3.91 | 12498886 | |
11 | S-nitrosocysteine | AAMIKKMCPSDSELS HHHHHHHCCCCCCCC | 3.91 | - | |
13 | Phosphorylation | MIKKMCPSDSELSIP HHHHHCCCCCCCCCC | 49.17 | 30631047 | |
15 | Phosphorylation | KKMCPSDSELSIPAK HHHCCCCCCCCCCCC | 44.78 | 30631047 | |
32 | Phosphorylation | YRMVILGSSKVGKTA EEEEEECCCCCCCHH | 24.44 | 30631047 | |
33 | Phosphorylation | RMVILGSSKVGKTAI EEEEECCCCCCCHHH | 29.57 | 30631047 | |
66 | Phosphorylation | DFHRKFYSIRGEVYQ HHHHHHHCCCCEEEE | 14.67 | 24719451 | |
92 (in isoform 2) | Phosphorylation | - | 17.46 | 30631047 | |
124 | Phosphorylation | LRQQILDTKSCLKNK HHHHHHCCHHHHCCC | 22.78 | 24702127 | |
182 | Phosphorylation | EISAKKNSSLDQMFR EEECCCCCCHHHHHH | 40.95 | 29978859 | |
183 | Phosphorylation | ISAKKNSSLDQMFRA EECCCCCCHHHHHHH | 45.41 | 29978859 | |
199 | Phosphorylation | FAMAKLPSEMSPDLH HHHHCCCHHCCHHHH | 57.26 | 29978859 | |
202 | Phosphorylation | AKLPSEMSPDLHRKV HCCCHHCCHHHHHHH | 15.94 | 29978859 | |
210 | Phosphorylation | PDLHRKVSVQYCDVL HHHHHHHHHHHHHHH | 13.41 | 24719451 | |
219 | Ubiquitination | QYCDVLHKKALRNKK HHHHHHCHHHHHCCC | 35.26 | 32142685 | |
232 | Phosphorylation | KKLLRAGSGGGGGDP CCCCCCCCCCCCCCH | 33.02 | 28355574 | |
254 | Phosphorylation | APFARRPSVHSDLMY CCCCCCCCCCCCHHH | 30.56 | 29978859 | |
257 | Phosphorylation | ARRPSVHSDLMYIRE CCCCCCCCCHHHHHH | 30.22 | 29978859 | |
261 | Phosphorylation | SVHSDLMYIREKASA CCCCCHHHHHHHHHC | 12.25 | 29978859 | |
267 | Phosphorylation | MYIREKASAGSQAKD HHHHHHHHCCCCCCC | 44.20 | 29083192 | |
270 | Phosphorylation | REKASAGSQAKDKER HHHHHCCCCCCCCCC | 27.04 | 29083192 | |
273 | Ubiquitination | ASAGSQAKDKERCVI HHCCCCCCCCCCCCC | 62.79 | 30230243 | |
278 | Methylation | QAKDKERCVIS---- CCCCCCCCCCC---- | 3.14 | - | |
278 | Farnesylation | QAKDKERCVIS---- CCCCCCCCCCC---- | 3.14 | - |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RASD1_HUMAN !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RASD1_HUMAN !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RASD1_HUMAN !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
CAPON_HUMAN | NOS1AP | physical | 11086993 | |
NOS1_HUMAN | NOS1 | physical | 11086993 | |
GNAI1_HUMAN | GNAI1 | physical | 10840027 | |
GBB1_HUMAN | GNB1 | physical | 16225846 | |
RBY1F_HUMAN | RBMY1F | physical | 25416956 |
Kegg Disease | ||||||
---|---|---|---|---|---|---|
There are no disease associations of PTM sites. | ||||||
OMIM Disease | ||||||
There are no disease associations of PTM sites. | ||||||
Kegg Drug | ||||||
There are no disease associations of PTM sites. | ||||||
DrugBank | ||||||
There are no disease associations of PTM sites. |
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