PRR3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PRR3_HUMAN
• UniProt AC: P79522
• Protein Name: Proline-rich protein 3
• Gene Name: PRR3
• Organism: Homo sapiens (Human).
• Sequence Length: 188
• Protein Sequence: MPKRKKQNHHQPPTQQQPPLPEREETGDEEDGSPIGPPSLLGPPPMANGKPGDPKSALHRGPPGSRGPLIPPLLSLPPPPWGRGPIRRGLGPRSSPYGRGWWGVNAEPPFPGPGHGGPTRGSFHKEQRNPRRLKSWSLIKNTCPPKDDPQVMEDKSDRPVCRHFAKKGHCRYEDLCAFYHPGVNGPPL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14 (in isoform 2)	Phosphorylation	-	45.77	21955146
14	Phosphorylation	QNHHQPPTQQQPPLP CCCCCCCCCCCCCCC	45.77	-
26	Phosphorylation	PLPEREETGDEEDGS CCCCCHHCCCCCCCC	45.22	22496350
26 (in isoform 2)	Phosphorylation	-	45.22	27273156
33	Phosphorylation	TGDEEDGSPIGPPSL CCCCCCCCCCCCHHH	26.18	22817900
33 (in isoform 2)	Phosphorylation	-	26.18	30266825
66	Methylation	HRGPPGSRGPLIPPL HCCCCCCCCCCCCCH	57.58	54558323
83	Methylation	LPPPPWGRGPIRRGL CCCCCCCCCCCCCCC	43.79	54558311
87	Methylation	PWGRGPIRRGLGPRS CCCCCCCCCCCCCCC	29.73	54558329
94	Phosphorylation	RRGLGPRSSPYGRGW CCCCCCCCCCCCCCC	38.51	20363803
95	Phosphorylation	RGLGPRSSPYGRGWW CCCCCCCCCCCCCCC	24.34	20363803
97	Phosphorylation	LGPRSSPYGRGWWGV CCCCCCCCCCCCCCC	22.77	24300666
99	Methylation	PRSSPYGRGWWGVNA CCCCCCCCCCCCCCC	31.54	58859159
119	Phosphorylation	GPGHGGPTRGSFHKE CCCCCCCCCCCCCHH	51.44	26074081
120	Dimethylation	PGHGGPTRGSFHKEQ CCCCCCCCCCCCHHH	41.72	-
120	Methylation	PGHGGPTRGSFHKEQ CCCCCCCCCCCCHHH	41.72	54558317
122	Phosphorylation	HGGPTRGSFHKEQRN CCCCCCCCCCHHHCC	22.38	26074081
125	Methylation	PTRGSFHKEQRNPRR CCCCCCCHHHCCHHH	54.23	115489133
135	Phosphorylation	RNPRRLKSWSLIKNT CCHHHHHHHHHHHCC	26.87	29978859
137	Phosphorylation	PRRLKSWSLIKNTCP HHHHHHHHHHHCCCC	27.58	24719451
142	Phosphorylation	SWSLIKNTCPPKDDP HHHHHHCCCCCCCCH	22.76	24719451
152	Sulfoxidation	PKDDPQVMEDKSDRP CCCCHHHCCCCCCCC	4.67	21406390

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PRR3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PRR3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PRR3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RBY1F_HUMAN	RBMY1F	physical	25416956
KHDR2_HUMAN	KHDRBS2	physical	25416956
CCD57_HUMAN	CCDC57	physical	25416956

Drug and Disease Associations

• Kegg Disease
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.