dbPTM

PRI2_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PRI2_DROME
UniProt AC	Q9VPH2
Protein Name	DNA primase large subunit
Gene Name	DNApol-alpha60
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	533
Subcellular Localization
Protein Description	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. Plays a role in the fat facets (faf)-dependent cell-communications pathway..
Protein Sequence	MEFGLKKRARHEVKVEVASLETKYPHNVMLYHYPPTEDVHIDEFEELALERLRLLRVLDRASTRNLRVLSDEWKEIVSADLTREGLRSYLRLCSTGGSAKHEADIQTRRRDYLSHFILRLAYCRSEDLARWFVAREMELFRYKFAALSSFEVKQFLEANGFEIHPLTEAQKDEVKDGLYESTVGQSVAKIELLDFYKVPFTQVLDLVRGRRCFLKAGYAYVNTHDLVSLVGTKQQDEIEQGLQAAKTMVEDVEADERISRTLKALHNSYTGRDYTVCRDAAVPIESLDQLSKTSMPLCMRMCHEHIRANHHIKHSGRMQYGLFLKGIGVALEDSLRFWREEFTKKMDADKFTRSYEYNIYHNYGKKGSMVNYTPYSCAKIIKDVAGPGDCHGCPYKNMDQGSLKTKLSSYGLSASAIDEVMFFVSRGHYQIGCGKYFQLTHNSPVEPSINHPNNYFEESQIAMGNRQKRANGSAPPKARIRPDIKGHGDRSMLMGDDDDELWRIAETQERIMQSQKDISEAFNDDLDLTQIDY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of PRI2_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PRI2_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PRI2_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PRI2_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ODR4_DROME	CG10616	physical	15575970
RAD51_DROME	spn-A	physical	15575970
RG68F_DROME	RhoGAP68F	physical	15575970

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PRI2_DROME

Related Literatures of Post-Translational Modification