| UniProt ID | PP12_SCHPO | |
|---|---|---|
| UniProt AC | P23880 | |
| Protein Name | Serine/threonine-protein phosphatase PP1-2 | |
| Gene Name | sds21 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 322 | |
| Subcellular Localization | ||
| Protein Description | Essential role in cell cycle control. PP1 is perhaps required for exit from mitosis.. | |
| Protein Sequence | MDYDIDAIIEKLVKARNGKPSKQVQLSDAEIRYLCTTSRSIFLSQPMLLELEAPLKICGDIHGQYSDLLRLFEYGGYPPDANYLFLGDYVDRGKQSLEVICLLFAYKIKYPENFFLLRGNHEFASINRIYGFYDECKRRYSIKLWKTFTDCFNCMPVAAVIDEKIFCMHGGLSPDLNSLDQIQRIIRPTDIPDTGLLCDLVWSDPEKDLTGWGENDRGVSYTFGADVVSRFLQKHDLDLICRAHQVVEDGYEFFGKRQLVTIFSAPNYCGEFDNVGAMMSVNEDLLCSFQILKPAEKRQRVSQSSIKESKSATNSLKKSKNN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 302 | Phosphorylation | AEKRQRVSQSSIKES HHHCHHCCHHHHHHH | 26.91 | 21712547 | |
| 304 | Phosphorylation | KRQRVSQSSIKESKS HCHHCCHHHHHHHHH | 26.90 | 21712547 | |
| 305 | Phosphorylation | RQRVSQSSIKESKSA CHHCCHHHHHHHHHH | 30.00 | 21712547 | |
| 313 | Phosphorylation | IKESKSATNSLKKSK HHHHHHHHHHHHHHC | 32.22 | 25720772 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PP12_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PP12_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PP12_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| RIF1_SCHPO | rif1 | physical | 24656819 | |
| HSP60_SCHPO | mcp60 | physical | 24945319 | |
| CMB1_SCHPO | cmb1 | physical | 24945319 | |
| YE99_SCHPO | glc9 | physical | 24945319 | |
| SDS22_SCHPO | sds22 | physical | 24945319 | |
| UCP3_SCHPO | ucp3 | physical | 24945319 | |
| RAD24_SCHPO | rad24 | physical | 24945319 | |
| LYS9_SCHPO | SPBC3B8.03 | physical | 24945319 | |
| TEA4_SCHPO | tea4 | physical | 24945319 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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