dbPTM

POT1A_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	POT1A_ARATH
UniProt AC	Q56Y52
Protein Name	Protection of telomeres protein 1a
Gene Name	POT1A
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	467
Subcellular Localization	Nucleus . Chromosome, telomere . Localizes to telomeres in S phase.
Protein Description	Component of the telomerase ribonucleoprotein (RNP) complex that is essential for positive telomere length regulation. Binds specifically the telomerase RNA template component TER1. Does not bind single-stranded telomeric DNA. Not required to recruit telomerase to telomeres, but stimulates TER1 RNP repeat addition processivity. [PubMed: 25329641]
Protein Sequence	MAKKRESPKLIKIKDAIKLINQQVSLIGIVLEQREPKQCRNNDWICTLRIIDDTYPSPGLTVNVFSKTLEQLPQIKNHDDMILFTRIKMQTFDSGERVNAACSRWVSSFALFEGVDFVCYQCSTNFHEEEALYKSAMDDLRKVFAGCSQVIKAMQSISYRTKPCSEVFSFLREIKIGKRFDLVCRILHADEDTSAVFVWDGTDAPPASILAKRSEEDKAFSSLSVHTLLSRDVLLSFPTVGTILRVHLSSHLFYRVKPGDWVKLYHLLCEVDRGSWVIKVTSSTKVHHLAQDDRLVEKIMRIYDKRLSSKLGHISFWCFPSPPGLTETDDNCAPFVTLMDIITFPKVTCKYRCIVRVVAAYPWQVEDFCSDENRRHHQVLLTLEDSTATLEAFLCNKDAEYFWGLGFQDTETLRKKRNWLLGIRESSNFVAPRNPPWIECCILSYYTNKADPWNTRLYRIFGTRLLH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of POT1A_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of POT1A_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of POT1A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of POT1A_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CBF5_ARATH	NAP57	physical	18212040
CTC1_ARATH	CTC1	physical	25697340
STN1_ARATH	STN1	physical	25697340
CTC1_ARATH	CTC1	physical	25329641
STN1_ARATH	STN1	physical	25329641
TRB1_ARATH	TRB1	physical	18387366
TRB2_ARATH	TRB2	physical	18387366
TRB3_ARATH	TRB3	physical	18387366

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of POT1A_ARATH

Related Literatures of Post-Translational Modification