PLD3B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PLD3B_HUMAN
• UniProt AC: Q9Y3B1
• Protein Name: PRELI domain containing protein 3B
• Gene Name: PRELID3B
• Organism: Homo sapiens (Human).
• Sequence Length: 194
• Protein Sequence: MKIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHIDPSGKLHSHRLLSTEWGLPSIVKSLIGAARTKTYVQEHSVVDPVEKTMELKSTNISFTNMVSVDERLIYKPHPQDPEKTVLTQEAIITVKGVSLSSYLEGLMASTISSNASKGREAMEWVIHKLNAEIEELTASARGTIRTPMAAAAFAEK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
46	Phosphorylation	LDRHIDPSGKLHSHR ECCCCCCCCCCCCCC		-
48	Acetylation	RHIDPSGKLHSHRLL CCCCCCCCCCCCCCC		7934217
48	Ubiquitination	RHIDPSGKLHSHRLL CCCCCCCCCCCCCCC		29967540
51	Phosphorylation	DPSGKLHSHRLLSTE CCCCCCCCCCCCCCC		-
56 (in isoform 2)	Phosphorylation	-		22210691
56	Phosphorylation	LHSHRLLSTEWGLPS CCCCCCCCCCCCCHH		28102081
57 (in isoform 2)	Phosphorylation	-		22210691
57	Phosphorylation	HSHRLLSTEWGLPSI CCCCCCCCCCCCHHH		28102081
67	Phosphorylation	GLPSIVKSLIGAART CCHHHHHHHHHHHHC		-
75 (in isoform 2)	Phosphorylation	-		22210691
75	Ubiquitination	LIGAARTKTYVQEHS HHHHHHCHHHHHHCC		21963094
76	Phosphorylation	IGAARTKTYVQEHSV HHHHHCHHHHHHCCC		29496907
77	Phosphorylation	GAARTKTYVQEHSVV HHHHCHHHHHHCCCC		29496907
90	Phosphorylation	VVDPVEKTMELKSTN CCCCCHHHEEEECCC		19413330
95	Phosphorylation	EKTMELKSTNISFTN HHHEEEECCCEEEEC		24641631
96	Phosphorylation	KTMELKSTNISFTNM HHEEEECCCEEEECC		24641631
99	Phosphorylation	ELKSTNISFTNMVSV EEECCCEEEECCEEE		24641631
101	Phosphorylation	KSTNISFTNMVSVDE ECCCEEEECCEEECC		24641631
105	Phosphorylation	ISFTNMVSVDERLIY EEEECCEEECCEEEE		24641631
112	Phosphorylation	SVDERLIYKPHPQDP EECCEEEECCCCCCC		-
136	Phosphorylation	IITVKGVSLSSYLEG EEEEECCCHHHHHHH		-
138	Phosphorylation	TVKGVSLSSYLEGLM EEECCCHHHHHHHHH		-
154	Phosphorylation	STISSNASKGREAME HHHHCCCHHHHHHHH		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PLD3B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PLD3B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PLD3B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TRIA1_HUMAN	TRIAP1	physical	27499296
PLD3B_HUMAN	SLMO2	physical	27499296
ECH1_HUMAN	ECH1	physical	27499296
SPKAP_HUMAN	SPHKAP	physical	27499296
C1QBP_HUMAN	C1QBP	physical	27499296

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.