PKP1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PKP1_ARATH
• UniProt AC: Q9LIK0
• Protein Name: Plastidial pyruvate kinase 1, chloroplastic
• Gene Name: PKP1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 596
• Subcellular Localization: Plastid, chloroplast stroma .
• Protein Description: Required for plastidial pyruvate kinase activity. Involved in seed oil accumulation, embryo development and seed storage compounds mobilization upon germination..
• Protein Sequence: MSQSIQFSTPSHTPHLLHLPHSQFNRPLSSISFRRFPLTTIKYTSIRASSSSSPSPDLDSSSSSSSSQVLLSPNGTGAVKSDERSVVATAVTTDTSGIEVDTVTEAELKENGFRSTRRTKLICTIGPATCGFEQLEALAVGGMNVARLNMCHGTRDWHRGVIRSVRRLNEEKGFAVAIMMDTEGSEIHMGDLGGEASAKAEDGEVWTFTVRAFDSSRPERTISVSYDGFAEDVRVGDELLVDGGMVRFEVIEKIGPDVKCLCTDPGLLLPRANLTFWRDGSLVRERNAMLPTISSKDWLDIDFGIAEGVDFIAVSFVKSAEVINHLKSYLAARSRGGEIGVIAKIESIDSLTNLEEIILASDGAMVARGDLGAQIPLEQVPAAQQRIVQVCRALNKPVIVASQLLESMIEYPTPTRAEVADVSEAVRQRSDALMLSGESAMGQFPDKALTVLRTVSLRIERWWREEKRHESVPLQAIGSSFSDKISEEICNSAAKMANNLGVDAVFVYTTSGHMASLVSRCRPDCPIFAFTTTTSVRRRLNLQWGLIPFRLSFSDDMESNLNKTFSLLKSRGMIKSGDLVIAVSDMLQSIQVMNVP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
294	Phosphorylation	NAMLPTISSKDWLDI CCCCCCCCCCCCCCC	33.54	28295753
295	Phosphorylation	AMLPTISSKDWLDID CCCCCCCCCCCCCCC	30.68	28295753
471	Phosphorylation	REEKRHESVPLQAIG HHHHCCCCCCHHHHC	23.94	19880383
482	Phosphorylation	QAIGSSFSDKISEEI HHHCCCCCHHHHHHH	39.68	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PKP1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PKP1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PKP1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
IF2B_ARATH	EIF2 BETA	physical	21798944
CIPKO_ARATH	SOS2	physical	21798944
WRKY7_ARATH	WRKY7	physical	21798944
DEF1B_ARATH	PDF1B	physical	21798944
PSB1_ARATH	PBF1	physical	21798944
UTP11_ARATH	EDA14	physical	21798944
CIPKE_ARATH	SR1	physical	21798944
GDI2_ARATH	GDI2	physical	21798944

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.