dbPTM

DEF1B_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	DEF1B_ARATH
UniProt AC	Q9FUZ2
Protein Name	Peptide deformylase 1B, chloroplastic/mitochondrial
Gene Name	PDF1B
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	273
Subcellular Localization	Plastid, chloroplast stroma. Mitochondrion. Reported to be localized to chloroplast and mitochondria based on transient GFP expression in a heterologous system.
Protein Description	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Has a preferred substrate specificity towards the photosystem II (PS II) D1 polypeptide..
Protein Sequence	MAVCNCFLQAPPLSRILLPVLSRRATTLSAGYGRLKSTVTFCSTVNRTSPLTSSVRAEVKRVSRKDDKVASATDVQFETPLKIVEYPDPILRAKNKRIDIFDENLKNLVDAMFDVMYKTDGIGLSAPQVGLNVQLMVFNPAGEPGEGKEIVLVNPKIKKYSDKLVPFDEGCLSFPGIYAEVVRPQSVKIDARDITGERFSISLSRLPARIFQHEYDHLEGVLFFDRMTDQVLDSIREELEALEKKYEEKTGLPSPERVEARQKRKAGVGFGKR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
48	Phosphorylation	FCSTVNRTSPLTSSV EEECCCCCCCCCHHH	29.50	24894044
49	Phosphorylation	CSTVNRTSPLTSSVR EECCCCCCCCCHHHH	18.06	24894044
52	Phosphorylation	VNRTSPLTSSVRAEV CCCCCCCCHHHHHHH	23.49	24894044
254	Phosphorylation	EEKTGLPSPERVEAR HHHHCCCCHHHHHHH	44.42	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of DEF1B_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of DEF1B_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of DEF1B_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of DEF1B_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of DEF1B_ARATH

Related Literatures of Post-Translational Modification