PIN2_ARATH - dbPTM
PIN2_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PIN2_ARATH
UniProt AC Q9LU77
Protein Name Auxin efflux carrier component 2 {ECO:0000303|PubMed:9843496}
Gene Name PIN2 {ECO:0000303|PubMed:9843496}
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 647
Subcellular Localization Cell membrane
Multi-pass membrane protein .
Protein Description Acts as a component of the auxin efflux carrier. Seems to be involved in the root-specific auxin transport, and mediates the root gravitropism. Its particular localization suggest a role in the translocation of auxin towards the elongation zone..
Protein Sequence MITGKDMYDVLAAMVPLYVAMILAYGSVRWWGIFTPDQCSGINRFVAVFAVPLLSFHFISSNDPYAMNYHFLAADSLQKVVILAALFLWQAFSRRGSLEWMITLFSLSTLPNTLVMGIPLLRAMYGDFSGNLMVQIVVLQSIIWYTLMLFLFEFRGAKLLISEQFPETAGSITSFRVDSDVISLNGREPLQTDAEIGDDGKLHVVVRRSSAASSMISSFNKSHGGGLNSSMITPRASNLTGVEIYSVQSSREPTPRASSFNQTDFYAMFNASKAPSPRHGYTNSYGGAGAGPGGDVYSLQSSKGVTPRTSNFDEEVMKTAKKAGRGGRSMSGELYNNNSVPSYPPPNPMFTGSTSGASGVKKKESGGGGSGGGVGVGGQNKEMNMFVWSSSASPVSEANAKNAMTRGSSTDVSTDPKVSIPPHDNLATKAMQNLIENMSPGRKGHVEMDQDGNNGGKSPYMGKKGSDVEDGGPGPRKQQMPPASVMTRLILIMVWRKLIRNPNTYSSLFGLAWSLVSFKWNIKMPTIMSGSISILSDAGLGMAMFSLGLFMALQPKIIACGKSVAGFAMAVRFLTGPAVIAATSIAIGIRGDLLHIAIVQAALPQGIVPFVFAKEYNVHPDILSTAVIFGMLVALPVTVLYYVLLGL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
209PhosphorylationLHVVVRRSSAASSMI
EEEEEECCCHHHHHH		17.4830407730
210PhosphorylationHVVVRRSSAASSMIS
EEEEECCCHHHHHHH		26.4930407730
213PhosphorylationVRRSSAASSMISSFN
EECCCHHHHHHHHCC		21.8430407730
214PhosphorylationRRSSAASSMISSFNK
ECCCHHHHHHHHCCH		18.5330407730
217PhosphorylationSAASSMISSFNKSHG
CHHHHHHHHCCHHCC		21.8930407730
218PhosphorylationAASSMISSFNKSHGG
HHHHHHHHCCHHCCC		23.1623111157
222PhosphorylationMISSFNKSHGGGLNS
HHHHCCHHCCCCCCH		28.5930407730
229PhosphorylationSHGGGLNSSMITPRA
HCCCCCCHHCCCCCH		26.7330407730
230PhosphorylationHGGGLNSSMITPRAS
CCCCCCHHCCCCCHH		17.0930407730
233PhosphorylationGLNSSMITPRASNLT
CCCHHCCCCCHHHCC		9.7030407730
237PhosphorylationSMITPRASNLTGVEI
HCCCCCHHHCCCCEE		33.38-
238N-linked_GlycosylationMITPRASNLTGVEIY
CCCCCHHHCCCCEEE		40.41-
258PhosphorylationREPTPRASSFNQTDF
CCCCCCCCCCCCHHH		36.4230589143
261N-linked_GlycosylationTPRASSFNQTDFYAM
CCCCCCCCCHHHHHH		45.87-
276PhosphorylationFNASKAPSPRHGYTN
EECCCCCCCCCCCCC		39.1523776212
309PhosphorylationSKGVTPRTSNFDEEV
CCCCCCCCCCCCHHH		29.2630407730
310PhosphorylationKGVTPRTSNFDEEVM
CCCCCCCCCCCHHHH		36.4630407730
354PhosphorylationNPMFTGSTSGASGVK
CCCCCCCCCCCCCCC		32.31-
365PhosphorylationSGVKKKESGGGGSGG
CCCCCCCCCCCCCCC		52.1730407730
370PhosphorylationKESGGGGSGGGVGVG
CCCCCCCCCCCCCCC		37.2230407730
389PhosphorylationEMNMFVWSSSASPVS
EEEEEEEECCCCCCC		14.7630407730
390PhosphorylationMNMFVWSSSASPVSE
EEEEEEECCCCCCCH		17.7630407730
391PhosphorylationNMFVWSSSASPVSEA
EEEEEECCCCCCCHH		27.5330407730
393PhosphorylationFVWSSSASPVSEANA
EEEECCCCCCCHHHH		27.9930407730
396PhosphorylationSSSASPVSEANAKNA
ECCCCCCCHHHHHHC		34.0830407730
405PhosphorylationANAKNAMTRGSSTDV
HHHHHCCCCCCCCCC		29.4830407730
408PhosphorylationKNAMTRGSSTDVSTD
HHCCCCCCCCCCCCC		27.1230407730
409PhosphorylationNAMTRGSSTDVSTDP
HCCCCCCCCCCCCCC		31.3030407730
410PhosphorylationAMTRGSSTDVSTDPK
CCCCCCCCCCCCCCC		41.9630407730
413PhosphorylationRGSSTDVSTDPKVSI
CCCCCCCCCCCCCCC		29.8730407730
414PhosphorylationGSSTDVSTDPKVSIP
CCCCCCCCCCCCCCC		57.0530407730
439PhosphorylationQNLIENMSPGRKGHV
HHHHHHCCCCCCCCC		35.4730589143
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PIN2_ARATH !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PIN2_ARATH !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PIN2_ARATH !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
FYPP1_ARATHAT1G50370physical
22715043
FYPP3_ARATHFYPP3physical
22715043
2AAA_ARATHRCN1physical
22715043
DPNP1_ARATHSAL1physical
22715043
AB19B_ARATHABCB19physical
17237354
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PIN2_ARATH

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Related Literatures of Post-Translational Modification

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