PHIPL_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PHIPL_HUMAN
• UniProt AC: Q96FC7
• Protein Name: Phytanoyl-CoA hydroxylase-interacting protein-like
• Gene Name: PHYHIPL
• Organism: Homo sapiens (Human).
• Sequence Length: 376
• Protein Description: May play a role in the development of the central system..
• Protein Sequence: MEVPRLDHALNSPTSPCEEVIKNLSLEAIQLCDRDGNKSQDSGIAEMEELPVPHNIKISNITCDSFKISWEMDSKSKDRITHYFIDLNKKENKNSNKFKHKDVPTKLVAKAVPLPMTVRGHWFLSPRTEYTVAVQTASKQVDGDYVVSEWSEIIEFCTADYSKVHLTQLLEKAEVIAGRMLKFSVFYRNQHKEYFDYVREHHGNAMQPSVKDNSGSHGSPISGKLEGIFFSCSTEFNTGKPPQDSPYGRYRFEIAAEKLFNPNTNLYFGDFYCMYTAYHYVILVIAPVGSPGDEFCKQRLPQLNSKDNKFLTCTEEDGVLVYHHAQDVILEVIYTDPVDLSVGTVAEITGHQLMSLSTANAKKDPSCKTCNISVGR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	RLDHALNSPTSPCEE CHHHHHCCCCCCHHH	30.33	22617229
14	Phosphorylation	DHALNSPTSPCEEVI HHHHCCCCCCHHHHH	45.16	22617229
15	Phosphorylation	HALNSPTSPCEEVIK HHHCCCCCCHHHHHH	30.82	24670416
23	N-linked_Glycosylation	PCEEVIKNLSLEAIQ CHHHHHHHCCHHHHH	24.60	UniProtKB CARBOHYD
25	Phosphorylation	EEVIKNLSLEAIQLC HHHHHHCCHHHHHCC	33.29	29116813
37	N-linked_Glycosylation	QLCDRDGNKSQDSGI HCCCCCCCCCCCCCC	45.13	UniProtKB CARBOHYD
65	Phosphorylation	ISNITCDSFKISWEM EEEEEECCEEEEEEE	30.50	24076635
69	Phosphorylation	TCDSFKISWEMDSKS EECCEEEEEEECCCC	19.99	26091039
81	Phosphorylation	SKSKDRITHYFIDLN CCCCCCEEEEEEECC	16.06	23917254
83	Phosphorylation	SKDRITHYFIDLNKK CCCCEEEEEEECCCC	8.12	23917254
84	Ubiquitination	KDRITHYFIDLNKKE CCCEEEEEEECCCCC	2.45	30230243
105	Phosphorylation	FKHKDVPTKLVAKAV CCCCCCCHHHHEEEE	36.54	-
110	Ubiquitination	VPTKLVAKAVPLPMT CCHHHHEEEECCCEE	42.30	30230243
117	Phosphorylation	KAVPLPMTVRGHWFL EEECCCEEEECEEEE	12.71	-
125	Phosphorylation	VRGHWFLSPRTEYTV EECEEEECCCCEEEE	11.67	20886841
146	Ubiquitination	KQVDGDYVVSEWSEI CCCCCCEEEECHHHH	4.55	30230243
172	Ubiquitination	HLTQLLEKAEVIAGR HHHHHHHHHHHHHHH	50.22	30230243
341	Phosphorylation	YTDPVDLSVGTVAEI ECCCCCCCCEEEEEE	17.65	25332170
349	Phosphorylation	VGTVAEITGHQLMSL CEEEEEECCHHHHCC	21.81	25332170
373	Phosphorylation	SCKTCNISVGR---- CCCCCCCEECC----	12.43	27732954
373	O-linked_Glycosylation	SCKTCNISVGR---- CCCCCCCEECC----	12.43	28657654

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PHIPL_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PHIPL_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PHIPL_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PHIPL_HUMAN	PHYHIPL	physical	27499296
OPA3_HUMAN	OPA3	physical	27499296
DHRS4_HUMAN	DHRS4	physical	27499296
MPPB_HUMAN	PMPCB	physical	27499296
STAR7_HUMAN	STARD7	physical	27499296
ECH1_HUMAN	ECH1	physical	27499296
C1QBP_HUMAN	C1QBP	physical	27499296
BACH_HUMAN	ACOT7	physical	27499296

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.