UniProt ID | PDZ11_HUMAN | |
---|---|---|
UniProt AC | Q5EBL8 | |
Protein Name | PDZ domain-containing protein 11 | |
Gene Name | PDZD11 | |
Organism | Homo sapiens (Human). | |
Sequence Length | 140 | |
Subcellular Localization |
Isoform 2: Secreted . Isoform 1: Cytoplasm . |
|
Protein Description | ||
Protein Sequence | MDSRIPYDDYPVVFLPAYENPPAWIPPHERVHHPDYNNELTQFLPRTITLKKPPGAQLGFNIRGGKASQLGIFISKVIPDSDAHRAGLQEGDQVLAVNDVDFQDIEHSKAVEILKTAREISMRVRFFPYNYHRQKERTVH | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
7 | Phosphorylation | -MDSRIPYDDYPVVF -CCCCCCCCCCCEEE | 21.05 | 21082442 | |
10 | Phosphorylation | SRIPYDDYPVVFLPA CCCCCCCCCEEEEEC | 8.60 | 20007894 | |
18 | Phosphorylation | PVVFLPAYENPPAWI CEEEEECCCCCCCCC | 17.82 | 25106551 | |
36 | Phosphorylation | ERVHHPDYNNELTQF CCCCCCCCCCHHHHH | 25.08 | 28796482 | |
49 | Phosphorylation | QFLPRTITLKKPPGA HHCCCEEECCCCCCC | 31.73 | 28857561 | |
68 | Phosphorylation | NIRGGKASQLGIFIS EEECCCHHHEEEEEE | 29.44 | - | |
109 | Ubiquitination | FQDIEHSKAVEILKT HHHCCHHHHHHHHHH | 59.36 | 29967540 | |
115 | Ubiquitination | SKAVEILKTAREISM HHHHHHHHHHHHHHH | 45.88 | 33845483 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PDZ11_HUMAN !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PDZ11_HUMAN !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PDZ11_HUMAN !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
SGMR1_HUMAN | SIGMAR1 | physical | 21988832 | |
PKHA5_HUMAN | PLEKHA5 | physical | 25416956 | |
CBY1_HUMAN | CBY1 | physical | 27173435 |
Kegg Disease | ||||||
---|---|---|---|---|---|---|
There are no disease associations of PTM sites. | ||||||
OMIM Disease | ||||||
There are no disease associations of PTM sites. | ||||||
Kegg Drug | ||||||
There are no disease associations of PTM sites. | ||||||
DrugBank | ||||||
There are no disease associations of PTM sites. |
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Phosphorylation | |
Reference | PubMed |
"An extensive survey of tyrosine phosphorylation revealing new sitesin human mammary epithelial cells."; Heibeck T.H., Ding S.-J., Opresko L.K., Zhao R., Schepmoes A.A.,Yang F., Tolmachev A.V., Monroe M.E., Camp D.G. II, Smith R.D.,Wiley H.S., Qian W.-J.; J. Proteome Res. 8:3852-3861(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-7 AND TYR-10, AND MASSSPECTROMETRY. | |
"Multiple reaction monitoring for robust quantitative proteomicanalysis of cellular signaling networks."; Wolf-Yadlin A., Hautaniemi S., Lauffenburger D.A., White F.M.; Proc. Natl. Acad. Sci. U.S.A. 104:5860-5865(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-7, AND MASSSPECTROMETRY. |