NRM_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NRM_HUMAN
• UniProt AC: Q8IXM6
• Protein Name: Nurim
• Gene Name: NRM
• Organism: Homo sapiens (Human).
• Sequence Length: 262
• Subcellular Localization: Nucleus inner membrane ; Multi-pass membrane protein .
• Protein Sequence: MAPALLLIPAALASFILAFGTGVEFVRFTSLRPLLGGIPESGGPDARQGWLAALQDRSILAPLAWDLGLLLLFVGQHSLMAAERVKAWTSRYFGVLQRSLYVACTALALQLVMRYWEPIPKGPVLWEARAEPWATWVPLLCFVLHVISWLLIFSILLVFDYAELMGLKQVYYHVLGLGEPLALKSPRALRLFSHLRHPVCVELLTVLWVVPTLGTDRLLLAFLLTLYLGLAHGLDQQDLRYLRAQLQRKLHLLSRPQDGEAE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
86	Ubiquitination	LMAAERVKAWTSRYF HHHHHHHHHHHHHHH	44.41	-
121	Ubiquitination	RYWEPIPKGPVLWEA HHHCCCCCCCCEECC	76.26	21890473
121	Ubiquitination	RYWEPIPKGPVLWEA HHHCCCCCCCCEECC	76.26	21890473
121 (in isoform 1)	Ubiquitination	-	76.26	21890473
171	Phosphorylation	LMGLKQVYYHVLGLG HCCCHHHHHHHHCCC	5.83	24043423
172	Phosphorylation	MGLKQVYYHVLGLGE CCCHHHHHHHHCCCC	6.13	24043423
184	Ubiquitination	LGEPLALKSPRALRL CCCCCCCCCHHHHHH	53.45	21890473
184	Ubiquitination	LGEPLALKSPRALRL CCCCCCCCCHHHHHH	53.45	21890473
184 (in isoform 1)	Ubiquitination	-	53.45	21890473
185	Phosphorylation	GEPLALKSPRALRLF CCCCCCCCHHHHHHH	22.07	26657352
225	Phosphorylation	LLLAFLLTLYLGLAH HHHHHHHHHHHHHHC	18.59	-
227	Phosphorylation	LAFLLTLYLGLAHGL HHHHHHHHHHHHCCC	8.09	-
249	Ubiquitination	LRAQLQRKLHLLSRP HHHHHHHHHHHHCCC	27.57	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NRM_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NRM_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NRM_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SUN2_HUMAN	SUN2	physical	25416956
CR3L1_HUMAN	CREB3L1	physical	25416956
TRI59_HUMAN	TRIM59	physical	25416956
CRNN_HUMAN	CRNN	physical	28514442
ZG16B_HUMAN	ZG16B	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.