N4BP2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: N4BP2_HUMAN
• UniProt AC: Q86UW6
• Protein Name: NEDD4-binding protein 2
• Gene Name: N4BP2
• Organism: Homo sapiens (Human).
• Sequence Length: 1770
• Subcellular Localization: Cytoplasm.
• Protein Description: Has 5'-polynucleotide kinase and nicking endonuclease activity. May play a role in DNA repair or recombination..
• Protein Sequence: MPRRRKNLGGNPFRKTANPKEVVVSSVASREEPTTTLPSMGETKVDQEELFTSISEIFSDLDPDVVYLMLSECDFKVENAMDCLLELSATDTKIEESSSQSFVASENQVGAAESKIMEKRPEEESEDSKMDSFLDMQLTEDLDSLIQNAFEKLNSSPDDQVYSFLPSQDVNSFNDSSEFINPDSSNMTPIFSTQNMNLNGENLENSGSTLSLNPLPSHSVLNESKCFIKDNTLALESNYPEDSLLSSSLNVASDSIAGCSSLNQKQKELLESECVEAQFSEAPVDLDASEPQACLNLPGLDLPGTGGDQKSTRVSDVFLPSEGFNFKPHKHPELPTKGKDVSYCPVLAPLPLLLPPPPPPPMWNPMIPAFDLFQGNHGFVAPVVTTAAHWRSVNYTFPPSVISHTSPTKVWRNKDGTSAYQVQETPVSQVVRKKTSYVGLVLVLLRGLPGSGKSFLARTLQEDNPSGVILSTDDYFYINGQYQFDVKYLGEAHEWNQNRAKEAFEKKISPIIIDNTNLQAWEMKPYVALSQKHKYKVLFREPDTWWKFKPKELARRNIHGVSKEKITRMLEHYQRFVSVPIIMSSSVPEKIERIELCAYSCEDRSTSPRDDEDIISEKEENILSLSLKHLEFTEEKNLDVTKETMLPENVAYLSNADLNKRRKEISDMNPSIQSALILETPHMYFSDSESKLQATDKSENEQIEMVAVKGYSKTDTDSSMERVSPSTCCSENNQEDCDLANSGPLQNEKSSPGEIVEERATVTKKAFGKQKSKSTLEKFPRHELSNFVGDWPVDKTIGQRTKRNRKTEKTSSVQSDKKYNYPQSHKLVNSVSVNTDCVQQRGSPHESVEDGRKSQCDDASEPLNSYKYDAYKNIDKNSFNIMGDWPSSDSLAQREHRSRMPKTGLSEPNLEIGTNDKMNEISLSTAHEACWGTSSQKLKTLGSSNLGSSEMLLSEMTCESQTCLSKKSHGQHTSLPLTFTNSAPTVSGVVEPQTLAECQEQMPKRDPGKEVGMCTQTEPQDFALLWKIEKNKISISDSIKVLTGRLDGFKPKVFNINTKSDVQEAIPYRVMYDKSTFVEESELTSADESENLNILCKLFGSFSLEALKDLYERCNKDIIWATSLLLDSETKLCEDTEFENFQKSCDGSQIGPFSLGLNLKEIISQRGTLENSNSPVPEFSHGIGISNADSQSTCDAERGNSEQAEMRAVTPENHESMTSIFPSAAVGLKNNNDILPNSQEELLYSSKQSFPGILKATTPKDMSETEKNLVVTETGDNIHSPSHFSDIFNFVSSTSNLELNEEIYFTDSLEIKRNENFPKDYVKFSDEEEFMNEDEKEMKEILMAGSSLSAGVSGEDKTEILNPTPAMAKSLTIDCLELALPPELAFQLNELFGPVGIDSGSLTVEDCVVHIDLNLAKVIHEKWKESVMERQRQEEVSCGKFMQDPSLVGHTGLDNPEQKSSQRTGKKLLKTLTASEMLPLLDHWNTQTKKVSLREIMSEEIALQEKHNLKRETLMFEKDCATKLKEKQLFKIFPAINQNFLVDIFKDHNYSLEHTVQFLNCVLEGDPVKTVVAQEFVHQNENVTSHTGQKSKEKKPKKLKETEETPSELSFQDFEYPDYDDYRAEAFLHQQKRMECYSKAKEAYRIGKKNVATFYAQQGTLHEQKMKEANHLAAIEIFEKVNASLLPQNVLDLHGLHVDEALEHLMRVLEKKTEEFKQNGGKPYLSVITGRGNHSQGGVARIKPAVIKYLISHSFRFSEIKPGCLKVMLK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Ubiquitination	--MPRRRKNLGGNPF --CCCCCCCCCCCCC	55.50	21890473
20	Ubiquitination	FRKTANPKEVVVSSV CCCCCCCCEEEEEEE	64.05	21890473
20 (in isoform 1)	Ubiquitination	-	64.05	21890473
20 (in isoform 2)	Ubiquitination	-	64.05	21890473
43	Phosphorylation	TLPSMGETKVDQEEL CCCCCCCCCCCHHHH	30.55	-
132	Phosphorylation	SEDSKMDSFLDMQLT CCCHHHHHHHHHHHH	24.98	17001009
162	Phosphorylation	SSPDDQVYSFLPSQD CCCCCCHHHCCCCCC	6.51	-
239	Phosphorylation	TLALESNYPEDSLLS EEEECCCCCCCHHHH	19.78	30576142
248	Phosphorylation	EDSLLSSSLNVASDS CCHHHHHCCCHHCCC	22.16	30576142
253	Phosphorylation	SSSLNVASDSIAGCS HHCCCHHCCCCCCCC	27.84	30576142
311	Phosphorylation	GTGGDQKSTRVSDVF CCCCCCCCCEECEEE	18.80	28555341
312	Phosphorylation	TGGDQKSTRVSDVFL CCCCCCCCEECEEEC	41.97	28555341
327	Ubiquitination	PSEGFNFKPHKHPEL CCCCCCCCCCCCCCC	47.52	-
330	Ubiquitination	GFNFKPHKHPELPTK CCCCCCCCCCCCCCC	70.18	-
337	Acetylation	KHPELPTKGKDVSYC CCCCCCCCCCCCCCC	63.12	22424773
337	Ubiquitination	KHPELPTKGKDVSYC CCCCCCCCCCCCCCC	63.12	-
400	Phosphorylation	VNYTFPPSVISHTSP CCCCCCHHHCCCCCC	32.11	24719451
405	Phosphorylation	PPSVISHTSPTKVWR CHHHCCCCCCCEEEE	29.61	24719451
406	Phosphorylation	PSVISHTSPTKVWRN HHHCCCCCCCEEEEC	25.75	26074081
408	Phosphorylation	VISHTSPTKVWRNKD HCCCCCCCEEEECCC	37.69	26074081
409	Ubiquitination	ISHTSPTKVWRNKDG CCCCCCCEEEECCCC	43.09	-
414	Ubiquitination	PTKVWRNKDGTSAYQ CCEEEECCCCCCCEE	49.30	21906983
414 (in isoform 1)	Ubiquitination	-	49.30	21890473
414 (in isoform 2)	Ubiquitination	-	49.30	21890473
420	Phosphorylation	NKDGTSAYQVQETPV CCCCCCCEEEECCCH	14.69	-
425	Phosphorylation	SAYQVQETPVSQVVR CCEEEECCCHHHHHH	16.35	28555341
453	Ubiquitination	RGLPGSGKSFLARTL HCCCCCCHHHHHHHH	39.47	-
454	Phosphorylation	GLPGSGKSFLARTLQ CCCCCCHHHHHHHHC	29.08	24719451
501	Ubiquitination	EWNQNRAKEAFEKKI HHHHHHHHHHHHHHC	46.46	-
507	Ubiquitination	AKEAFEKKISPIIID HHHHHHHHCCCEEEC	41.02	-
524	Ubiquitination	NLQAWEMKPYVALSQ CCCEECCCCEEECCC	22.98	-
532	Ubiquitination	PYVALSQKHKYKVLF CEEECCCCCCEEEEE	38.39	-
534	Ubiquitination	VALSQKHKYKVLFRE EECCCCCCEEEEECC	54.52	-
544	Phosphorylation	VLFREPDTWWKFKPK EEECCCCCCCCCCHH	43.89	30631047
551	Ubiquitination	TWWKFKPKELARRNI CCCCCCHHHHHHCCC	66.98	-
563	Ubiquitination	RNIHGVSKEKITRML CCCCCCCHHHHHHHH	61.70	-
573	Phosphorylation	ITRMLEHYQRFVSVP HHHHHHHHHHHHCCC	7.63	30243723
578	Phosphorylation	EHYQRFVSVPIIMSS HHHHHHHCCCEEECC	21.33	30243723
584	Phosphorylation	VSVPIIMSSSVPEKI HCCCEEECCCCCHHH	14.73	30243723
585	Phosphorylation	SVPIIMSSSVPEKIE CCCEEECCCCCHHHH	20.27	30243723
586	Phosphorylation	VPIIMSSSVPEKIER CCEEECCCCCHHHHH	34.09	30243723
590	Acetylation	MSSSVPEKIERIELC ECCCCCHHHHHEEEE	43.74	23236377
590	Ubiquitination	MSSSVPEKIERIELC ECCCCCHHHHHEEEE	43.74	-
599	Phosphorylation	ERIELCAYSCEDRST HHEEEEEEECCCCCC	16.92	29978859
600	Phosphorylation	RIELCAYSCEDRSTS HEEEEEEECCCCCCC	7.78	29978859
605	Phosphorylation	AYSCEDRSTSPRDDE EEECCCCCCCCCCCH	45.63	28450419
606	Phosphorylation	YSCEDRSTSPRDDED EECCCCCCCCCCCHH	43.58	28450419
607	Phosphorylation	SCEDRSTSPRDDEDI ECCCCCCCCCCCHHH	21.13	28450419
616	Phosphorylation	RDDEDIISEKEENIL CCCHHHCCHHHHHHH	42.84	26074081
624	Phosphorylation	EKEENILSLSLKHLE HHHHHHHHHHHHHHH	16.47	26074081
626	Phosphorylation	EENILSLSLKHLEFT HHHHHHHHHHHHHCC	31.81	25159151
628	Ubiquitination	NILSLSLKHLEFTEE HHHHHHHHHHHCCCC	42.65	-
633	Phosphorylation	SLKHLEFTEEKNLDV HHHHHHCCCCCCCCC	33.58	26074081
636	Ubiquitination	HLEFTEEKNLDVTKE HHHCCCCCCCCCCHH	57.49	-
642	Ubiquitination	EKNLDVTKETMLPEN CCCCCCCHHHCCCCH	51.54	21906983
642 (in isoform 1)	Ubiquitination	-	51.54	21890473
642 (in isoform 2)	Ubiquitination	-	51.54	21890473
644	Phosphorylation	NLDVTKETMLPENVA CCCCCHHHCCCCHHH	26.09	22461510
652	Phosphorylation	MLPENVAYLSNADLN CCCCHHHHHCHHCHH	13.33	21945579
654	Phosphorylation	PENVAYLSNADLNKR CCHHHHHCHHCHHHH	19.80	21945579
660	Ubiquitination	LSNADLNKRRKEISD HCHHCHHHHHHHHHH	61.96	-
686	Phosphorylation	ETPHMYFSDSESKLQ CCCCEECCCCHHHCC	23.80	-
690	Phosphorylation	MYFSDSESKLQATDK EECCCCHHHCCCCCC	42.49	-
709	Ubiquitination	QIEMVAVKGYSKTDT CEEEEEEECCCCCCC	42.25	-
714	Phosphorylation	AVKGYSKTDTDSSME EEECCCCCCCCCCCC	37.89	20860994
719	Phosphorylation	SKTDTDSSMERVSPS CCCCCCCCCCCCCHH	27.72	30576142
724	Phosphorylation	DSSMERVSPSTCCSE CCCCCCCCHHHCCCC	21.25	30576142
726	Phosphorylation	SMERVSPSTCCSENN CCCCCCHHHCCCCCC	26.94	25850435
727	Phosphorylation	MERVSPSTCCSENNQ CCCCCHHHCCCCCCH	22.40	25850435
730	Phosphorylation	VSPSTCCSENNQEDC CCHHHCCCCCCHHCC	45.57	30576142
742	Phosphorylation	EDCDLANSGPLQNEK HCCCCCCCCCCCCCC	35.86	27732954
750	Phosphorylation	GPLQNEKSSPGEIVE CCCCCCCCCCCCHHH	35.27	23401153
751	Phosphorylation	PLQNEKSSPGEIVEE CCCCCCCCCCCHHHH	48.25	19664994
761	Phosphorylation	EIVEERATVTKKAFG CHHHHHHHHCHHHHC	34.62	29759185
763	Phosphorylation	VEERATVTKKAFGKQ HHHHHHHCHHHHCCC	23.60	29759185
772	Phosphorylation	KAFGKQKSKSTLEKF HHHCCCCCHHHHHHC	29.37	23312004
774	Phosphorylation	FGKQKSKSTLEKFPR HCCCCCHHHHHHCCH	45.36	23312004
775	Phosphorylation	GKQKSKSTLEKFPRH CCCCCHHHHHHCCHH	42.55	23312004
778	Ubiquitination	KSKSTLEKFPRHELS CCHHHHHHCCHHHHH	64.87	-
795	Acetylation	VGDWPVDKTIGQRTK CCCCCCCCHHHHHCC	42.13	25953088
796	Phosphorylation	GDWPVDKTIGQRTKR CCCCCCCHHHHHCCC	26.35	-
807	Phosphorylation	RTKRNRKTEKTSSVQ HCCCCCCCCCCCCCC	39.20	-
811	Phosphorylation	NRKTEKTSSVQSDKK CCCCCCCCCCCCCCC	39.31	-
819	Phosphorylation	SVQSDKKYNYPQSHK CCCCCCCCCCCCCCC	26.18	28796482
821	Phosphorylation	QSDKKYNYPQSHKLV CCCCCCCCCCCCCCC	10.27	28796482
826	Acetylation	YNYPQSHKLVNSVSV CCCCCCCCCCCEEEC	60.42	25953088
830	Phosphorylation	QSHKLVNSVSVNTDC CCCCCCCEEECCCHH	14.32	29978859
832	Phosphorylation	HKLVNSVSVNTDCVQ CCCCCEEECCCHHHH	14.96	29978859
835	Phosphorylation	VNSVSVNTDCVQQRG CCEEECCCHHHHCCC	28.72	29978859
843	Phosphorylation	DCVQQRGSPHESVED HHHHCCCCCCCCCCC	25.85	25159151
854	Phosphorylation	SVEDGRKSQCDDASE CCCCCCCCCCCCCCC	34.38	25159151
867	Ubiquitination	SEPLNSYKYDAYKNI CCCHHHHCHHHCCCC	36.15	-
872	Ubiquitination	SYKYDAYKNIDKNSF HHCHHHCCCCCCCCC	49.50	-
876	Ubiquitination	DAYKNIDKNSFNIMG HHCCCCCCCCCEECC	51.17	-
887	Phosphorylation	NIMGDWPSSDSLAQR EECCCCCCCHHHHHH	42.39	28348404
898	Phosphorylation	LAQREHRSRMPKTGL HHHHHHHHCCCCCCC	34.53	17081983
902	Ubiquitination	EHRSRMPKTGLSEPN HHHHCCCCCCCCCCC	45.97	-
903	Phosphorylation	HRSRMPKTGLSEPNL HHHCCCCCCCCCCCC	37.17	27251275
906	Phosphorylation	RMPKTGLSEPNLEIG CCCCCCCCCCCCCCC	52.96	28450419
948	Phosphorylation	LGSSNLGSSEMLLSE CCCCCCCCHHHHHHH	26.70	28348404
949	Phosphorylation	GSSNLGSSEMLLSEM CCCCCCCHHHHHHHC	25.81	28348404
954	Phosphorylation	GSSEMLLSEMTCESQ CCHHHHHHHCCCCCC	22.74	28985074
957	Phosphorylation	EMLLSEMTCESQTCL HHHHHHCCCCCCCCC	14.74	28985074
965	Phosphorylation	CESQTCLSKKSHGQH CCCCCCCCCCCCCCC	39.94	28985074
967	Ubiquitination	SQTCLSKKSHGQHTS CCCCCCCCCCCCCCC	44.29	-
1027	Ubiquitination	QDFALLWKIEKNKIS CCEEEEEEECCCCCC	40.74	-
1030	Ubiquitination	ALLWKIEKNKISISD EEEEEECCCCCCHHH	67.99	-
1032	Ubiquitination	LWKIEKNKISISDSI EEEECCCCCCHHHHH	49.23	-
1034	Phosphorylation	KIEKNKISISDSIKV EECCCCCCHHHHHHH	20.04	-
1036	Phosphorylation	EKNKISISDSIKVLT CCCCCCHHHHHHHHH	20.65	20363803
1040	Ubiquitination	ISISDSIKVLTGRLD CCHHHHHHHHHCCCC	34.83	-
1050	Ubiquitination	TGRLDGFKPKVFNIN HCCCCCCCCEEEECC	49.84	-
1052	Ubiquitination	RLDGFKPKVFNINTK CCCCCCCEEEECCCC	61.11	-
1059	Ubiquitination	KVFNINTKSDVQEAI EEEECCCCCCHHHHC	39.92	-
1074	Ubiquitination	PYRVMYDKSTFVEES CCEEEECCCCCEEHH	33.63	-
1143	Ubiquitination	TEFENFQKSCDGSQI CCCHHHHHHCCCCCC	49.25	-
1168	Phosphorylation	EIISQRGTLENSNSP HHHHHHCCCCCCCCC	32.84	27050516
1172	Phosphorylation	QRGTLENSNSPVPEF HHCCCCCCCCCCCCC	29.34	-
1174	Phosphorylation	GTLENSNSPVPEFSH CCCCCCCCCCCCCCC	27.39	-
1186	Phosphorylation	FSHGIGISNADSQST CCCCCCCCCCCCCCC	22.28	-
1192	Phosphorylation	ISNADSQSTCDAERG CCCCCCCCCCCCCCC	34.65	-
1201	Phosphorylation	CDAERGNSEQAEMRA CCCCCCCHHHHHHCC	33.63	-
1210	Phosphorylation	QAEMRAVTPENHESM HHHHCCCCCCCHHHH	24.73	23401153
1216	Phosphorylation	VTPENHESMTSIFPS CCCCCHHHHHHHCCH	21.58	30266825
1218	Phosphorylation	PENHESMTSIFPSAA CCCHHHHHHHCCHHH	28.13	29255136
1219	Phosphorylation	ENHESMTSIFPSAAV CCHHHHHHHCCHHHH	17.37	29255136
1223	Phosphorylation	SMTSIFPSAAVGLKN HHHHHCCHHHHCCCC	20.36	23403867
1229	Ubiquitination	PSAAVGLKNNNDILP CHHHHCCCCCCCCCC	52.26	-
1238	Phosphorylation	NNDILPNSQEELLYS CCCCCCCCHHHHHHH	36.71	25159151
1244	Phosphorylation	NSQEELLYSSKQSFP CCHHHHHHHCCCCCC	24.43	25159151
1247	Ubiquitination	EELLYSSKQSFPGIL HHHHHHCCCCCCCCC	43.98	21906983
1247 (in isoform 1)	Ubiquitination	-	43.98	21890473
1247 (in isoform 2)	Ubiquitination	-	43.98	21890473
1255	Ubiquitination	QSFPGILKATTPKDM CCCCCCCCCCCCCCC	41.59	-
1257	Phosphorylation	FPGILKATTPKDMSE CCCCCCCCCCCCCCH	41.88	26074081
1258	Phosphorylation	PGILKATTPKDMSET CCCCCCCCCCCCCHH	32.95	26074081
1260	Ubiquitination	ILKATTPKDMSETEK CCCCCCCCCCCHHHC	65.06	-
1263	Phosphorylation	ATTPKDMSETEKNLV CCCCCCCCHHHCCEE	52.04	26074081
1265	Phosphorylation	TPKDMSETEKNLVVT CCCCCCHHHCCEEEE	44.98	26074081
1280	Phosphorylation	ETGDNIHSPSHFSDI ECCCCCCCCCHHHHH	25.05	26074081
1282	Phosphorylation	GDNIHSPSHFSDIFN CCCCCCCCHHHHHHH	39.93	26074081
1285	Phosphorylation	IHSPSHFSDIFNFVS CCCCCHHHHHHHHHH	25.11	26074081
1321	Phosphorylation	NENFPKDYVKFSDEE CCCCCHHHCCCCCHH	16.21	25002506
1325	Phosphorylation	PKDYVKFSDEEEFMN CHHHCCCCCHHHHCC	38.09	25159151
1339	Ubiquitination	NEDEKEMKEILMAGS CCCHHHHHHHHHHCC	42.57	21906983
1339 (in isoform 1)	Ubiquitination	-	42.57	21890473
1339 (in isoform 2)	Ubiquitination	-	42.57	21890473
1346	Phosphorylation	KEILMAGSSLSAGVS HHHHHHCCCCCCCCC	20.68	23403867
1347	Phosphorylation	EILMAGSSLSAGVSG HHHHHCCCCCCCCCC	25.98	23403867
1349	Phosphorylation	LMAGSSLSAGVSGED HHHCCCCCCCCCCCC	25.56	20860994
1353	Phosphorylation	SSLSAGVSGEDKTEI CCCCCCCCCCCCCCC	35.23	-
1422	Ubiquitination	LAKVIHEKWKESVME HHHHHHHHHHHHHHH	49.78	-
1424	Acetylation	KVIHEKWKESVMERQ HHHHHHHHHHHHHHH	51.70	19820247
1424	Ubiquitination	KVIHEKWKESVMERQ HHHHHHHHHHHHHHH	51.70	-
1440	Acetylation	QEEVSCGKFMQDPSL HHHHCCCHHCCCHHH	41.83	25953088
1440	Ubiquitination	QEEVSCGKFMQDPSL HHHHCCCHHCCCHHH	41.83	21906983
1440 (in isoform 1)	Ubiquitination	-	41.83	21890473
1440 (in isoform 2)	Ubiquitination	-	41.83	21890473
1459	Ubiquitination	GLDNPEQKSSQRTGK CCCCHHHHHHHHHHH	50.87	2190698
1459 (in isoform 1)	Ubiquitination	-	50.87	21890473
1459 (in isoform 2)	Ubiquitination	-	50.87	21890473
1470	Ubiquitination	RTGKKLLKTLTASEM HHHHHHHHHHCHHHH	52.50	-
1471	Phosphorylation	TGKKLLKTLTASEML HHHHHHHHHCHHHHH	29.34	-
1473	Phosphorylation	KKLLKTLTASEMLPL HHHHHHHCHHHHHHH	33.11	28348404
1489	Ubiquitination	DHWNTQTKKVSLREI HHCCCCCCEECHHHH	41.16	-
1490	Ubiquitination	HWNTQTKKVSLREIM HCCCCCCEECHHHHH	40.21	-
1506	Ubiquitination	EEIALQEKHNLKRET HHHHHHHHHCCCHHH	25.49	-
1510	Ubiquitination	LQEKHNLKRETLMFE HHHHHCCCHHHHHCC	54.21	-
1518	Ubiquitination	RETLMFEKDCATKLK HHHHHCCHHHHHHHH	47.01	-
1527	Ubiquitination	CATKLKEKQLFKIFP HHHHHHHHHHHHHHH	51.19	-
1600	Ubiquitination	EKKPKKLKETEETPS CCCCCCCCCCCCCCC	72.04	-
1602	Phosphorylation	KPKKLKETEETPSEL CCCCCCCCCCCCCCC	37.22	28796482
1605	Phosphorylation	KLKETEETPSELSFQ CCCCCCCCCCCCCCC	26.36	28796482
1607	Phosphorylation	KETEETPSELSFQDF CCCCCCCCCCCCCCC	59.60	28796482
1610	Phosphorylation	EETPSELSFQDFEYP CCCCCCCCCCCCCCC	19.46	-
1616	Phosphorylation	LSFQDFEYPDYDDYR CCCCCCCCCCHHHHH	11.03	28796482
1619	Phosphorylation	QDFEYPDYDDYRAEA CCCCCCCHHHHHHHH	13.25	28796482
1622	Phosphorylation	EYPDYDDYRAEAFLH CCCCHHHHHHHHHHH	14.61	28796482
1632	Ubiquitination	EAFLHQQKRMECYSK HHHHHHHHHHHHHHH	47.33	-
1639	Ubiquitination	KRMECYSKAKEAYRI HHHHHHHHHHHHHHH	36.68	-
1649	Ubiquitination	EAYRIGKKNVATFYA HHHHHCCHHHHHHHH	51.98	-
1655	Phosphorylation	KKNVATFYAQQGTLH CHHHHHHHHHCCCCC	10.11	27642862
1665	Ubiquitination	QGTLHEQKMKEANHL CCCCCHHHHHHCCHH	49.29	-
1667	Ubiquitination	TLHEQKMKEANHLAA CCCHHHHHHCCHHHH	61.79	-
1717	Ubiquitination	EKKTEEFKQNGGKPY HHHHHHHHHCCCCEE	46.24	-
1722	Acetylation	EFKQNGGKPYLSVIT HHHHCCCCEEEEEEE	31.71	25953088
1722	Ubiquitination	EFKQNGGKPYLSVIT HHHHCCCCEEEEEEE	31.71	-
1724	Phosphorylation	KQNGGKPYLSVITGR HHCCCCEEEEEEECC	18.33	20090780
1735	Phosphorylation	ITGRGNHSQGGVARI EECCCCCCCCCCCCC	34.22	23532336
1761	Acetylation	SFRFSEIKPGCLKVM CCCHHHCCCCCEEEC	31.16	25953088
1761	Ubiquitination	SFRFSEIKPGCLKVM CCCHHHCCCCCEEEC	31.16	-
1766	Ubiquitination	EIKPGCLKVMLK--- HCCCCCEEECCC---	29.67	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of N4BP2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of N4BP2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of N4BP2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CBP_HUMAN	CREBBP	physical	12730195
BCL3_HUMAN	BCL3	physical	12730195
N4BP2_HUMAN	N4BP2	physical	22072629

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis.";
Wang B., Malik R., Nigg E.A., Korner R.;
Anal. Chem. 80:9526-9533(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-750, AND MASSSPECTROMETRY.
PubMed: 19007248

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-898, AND MASSSPECTROMETRY.
PubMed: 17081983