MPEG1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MPEG1_MOUSE
• UniProt AC: A1L314
• Protein Name: Macrophage-expressed gene 1 protein
• Gene Name: Mpeg1
• Organism: Mus musculus (Mouse).
• Sequence Length: 713
• Subcellular Localization: Membrane ; Single-pass type I membrane protein .
• Protein Sequence: MNSFMALVLIWMIIACAEADKPLGETGTTGFQICKNALKLPVLEVLPGGGWDNLRNVDMGRVMDLTYTNCKTTEDGQYIIPDEVYTIPQKESNLEMNSEVLESWMNYQSTTSLSINTELALFSRVNGKFSTEFQRMKTLQVKDQAVTTRVQVRNRIYTVKTTPTSELSLGFTKALMDICDQLEKNQTKMATYLAELLILNYGTHVITSVDAGAALVQEDHVRSSFLLDNQNSQNTVTASAGIAFLNIVNFKVETDYISQTSLTKDYLSNRTNSRVQSFGGVPFYPGITLETWQKGITNHLVAIDRAGLPLHFFIKPDKLPGLPGPLVKKLSKTVETAVRHYYTFNTHPGCTNVDSPNFNFQANMDDDSCDAKVTNFTFGGVYQECTELSGDVLCQNLEQKNLLTGDFSCPPGYSPVHLLSQTHEEGYSRLECKKKCTLKIFCKTVCEDVFRVAKAEFRAYWCVAAGQVPDNSGLLFGGVFTDKTINPMTNAQSCPAGYIPLNLFESLKVCVSLDYELGFKFSVPFGGFFSCIMGNPLVNSDTAKDVRAPSLKKCPGGFSQHLAVISDGCQVSYCVKAGIFTGGSLLPVRLPPYTKPPLMSQVATNTVIVTNSETARSWIKDPQTNQWKLGEPLELRRAMTVIHGDSNGMSGGEAAGITLGVTIALGIVITLAIYGTRKYKKKEYQEIEEQESLVGSLATDATVLNGEEDPSPA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
185	N-linked_Glycosylation	ICDQLEKNQTKMATY HHHHHHHHHHHHHHH	45.43	-
269	N-linked_Glycosylation	LTKDYLSNRTNSRVQ CCHHHHCCCCCCCCC	52.80	-
375	N-linked_Glycosylation	SCDAKVTNFTFGGVY CCCEEEEEEEECHHH	36.63	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MPEG1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MPEG1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MPEG1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UBC12_MOUSE	Ube2m	physical	26418746
CUL1_MOUSE	Cul1	physical	26418746
FBW1A_MOUSE	Btrc	physical	26418746

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.