MOB3B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MOB3B_HUMAN
• UniProt AC: Q86TA1
• Protein Name: MOB kinase activator 3B
• Gene Name: MOB3B {ECO:0000312|HGNC:HGNC:23825}
• Organism: Homo sapiens (Human).
• Sequence Length: 216
• Protein Description: May regulate the activity of kinases..
• Protein Sequence: MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWVAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNLLMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEAHVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Phosphorylation	QVFNKDKTFRPKRKF HHHCCCCCCCCCCCC	34.70	-
20	Acetylation	KTFRPKRKFEPGTQR CCCCCCCCCCCCCCC	61.27	25953088
20	Ubiquitination	KTFRPKRKFEPGTQR CCCCCCCCCCCCCCC	61.27	-
25	Phosphorylation	KRKFEPGTQRFELHK CCCCCCCCCCHHHHH	27.56	28060719
37	Phosphorylation	LHKRAQASLNSGVDL HHHHHHHHHHCCCCE	18.92	28857561
77	Phosphorylation	RINLIYGTICEFCTE HHHHHHHHHHHHHCC	12.89	-
86	Phosphorylation	CEFCTERTCPVMSGG HHHHCCCCCCCCCCC	18.22	23898821
91	Phosphorylation	ERTCPVMSGGPKYEY CCCCCCCCCCCCCEE	40.61	23898821
96	Phosphorylation	VMSGGPKYEYRWQDD CCCCCCCCEEECCCC	22.71	25404012
98	Phosphorylation	SGGPKYEYRWQDDLK CCCCCCEEECCCCCC	17.67	25404012
190	Phosphorylation	NTCYKHFYYFVTEMN HHHHHHHHHHHHHCC	8.84	25907765
191	Phosphorylation	TCYKHFYYFVTEMNL HHHHHHHHHHHHCCC	7.22	25907765
194	Phosphorylation	KHFYYFVTEMNLIDR HHHHHHHHHCCCCCH	21.44	25907765
208	Ubiquitination	RKELEPLKEMTSRMC HHHCHHHHHHHHHHC	57.04	29967540

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MOB3B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MOB3B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MOB3B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CXCL7_HUMAN	PPBP	physical	21900206
LATS1_HUMAN	LATS1	physical	19739119
LATS2_HUMAN	LATS2	physical	19739119
5NTC_HUMAN	NT5C2	physical	19060904

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.