MOB3A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MOB3A_HUMAN
• UniProt AC: Q96BX8
• Protein Name: MOB kinase activator 3A
• Gene Name: MOB3A
• Organism: Homo sapiens (Human).
• Sequence Length: 217
• Protein Description: May regulate the activity of kinases..
• Protein Sequence: MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSNPFLKQV ------CCCHHHHHH	53.89	24719451
7	Ubiquitination	-MSNPFLKQVFNKDK -CCCHHHHHHHCCCC	44.81	-
15	Phosphorylation	QVFNKDKTFRPKRKF HHHCCCCCCCCCCCC	34.70	-
21	Ubiquitination	KTFRPKRKFEPGTQR CCCCCCCCCCCCCCC	61.27	29967540
26	Phosphorylation	KRKFEPGTQRFELHK CCCCCCCCCCHHHHH	27.56	28060719
38	Phosphorylation	LHKKAQASLNAGLDL HHHHHHHHHHCCCCE	15.29	28450419
96	Sumoylation	PVMSGGPKYEYRWQD CCCCCCCCCEEEECC	54.73	-
106	Ubiquitination	YRWQDEHKFRKPTAL EEECCCCCCCCCCCC	44.83	-
109	Ubiquitination	QDEHKFRKPTALSAP CCCCCCCCCCCCCCH	50.26	-
111	Phosphorylation	EHKFRKPTALSAPRY CCCCCCCCCCCCHHH	43.18	22673903
114	Phosphorylation	FRKPTALSAPRYMDL CCCCCCCCCHHHHHH	33.49	23312004
203	Ubiquitination	EFGLIDTKELEPLKE HHCCCCHHCCHHHHH	57.46	29967540
209	Ubiquitination	TKELEPLKEMTARMC HHCCHHHHHHHHHHC	57.04	29967540
212	Phosphorylation	LEPLKEMTARMCH-- CHHHHHHHHHHCC--	16.53	28857561

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MOB3A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MOB3A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MOB3A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
LATS1_HUMAN	LATS1	physical	19739119
LATS2_HUMAN	LATS2	physical	19739119
A4_HUMAN	APP	physical	21832049
TGIF1_HUMAN	TGIF1	physical	21516116

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.