MFRN_DROME - dbPTM
MFRN_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MFRN_DROME
UniProt AC Q9VAY3
Protein Name Mitoferrin
Gene Name mfrn
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 379
Subcellular Localization Mitochondrion inner membrane
Multi-pass membrane protein .
Protein Description Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly..
Protein Sequence MNIDDYESLPTTSVGVNMTAGAIAGVLEHVVMYPLDSVKTRMQSLSPPTKNMNIVSTLRTMITREGLLRPIRGASAVVLGAGPAHSLYFAAYEMTKELTAKFTSVRNLNYVISGAVATLIHDAISSPTDVIKQRMQMYNSPYTSVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHFTTYEFFQNKMNLERKYNPPVHMAAGAAAGACAAAVTTPLDVIKTLLNTQETGLTRGMIEASRKIYHMAGPLGFFRGTTARVLYSMPATAICWSTYEFFKFYLCGLDADQYKSSITGSSEPRKADYVLPRTTDEEQIDQEREAAKEKDTTATLHSAPTSVNASGAIKTVCELSTRPAGPTINLHTRHTDVKSPYERGFST
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of MFRN_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MFRN_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MFRN_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MFRN_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CDK1_DROMEcdc2physical
14605208
EF1B_DROMEEf1betaphysical
14605208
TBB1_DROMEbetaTub56Dphysical
14605208

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MFRN_DROME

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Related Literatures of Post-Translational Modification

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