MB211_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MB211_HUMAN
• UniProt AC: Q13394
• Protein Name: Putative nucleotidyltransferase MAB21L1 {ECO:0000305}
• Gene Name: MAB21L1 {ECO:0000312|HGNC:HGNC:6757}
• Organism: Homo sapiens (Human).
• Sequence Length: 359
• Subcellular Localization: Nucleus .
• Protein Description: Putative nucleotidyltransferase required for several aspects of embryonic development including normal development of the eye (By similarity). It is unclear whether it displays nucleotidyltransferase activity in vivo. [PubMed: 27271801 Binds single-stranded RNA (ssRNA)]
• Protein Sequence: MIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHSLAGKQSSAESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	AAQAKLVYHLNKYYN HHHHHHHHHHHHHHH	15.83	22817900
15	Phosphorylation	LVYHLNKYYNEKCQA HHHHHHHHHHHHHHH	15.51	22817900
16	Phosphorylation	VYHLNKYYNEKCQAR HHHHHHHHHHHHHHH	20.60	22817900
39	Phosphorylation	REVCKVVSDVLKEVE HHHHHHHHHHHHHCC	25.62	-
109	Phosphorylation	LSDGRKRSMSLWVEF CCCCCCEEHHHHHHH	18.76	-
130	Phosphorylation	LSARKIRSRFQTLVA HHHHHHHHHHHHHHH	40.70	-
134	Phosphorylation	KIRSRFQTLVAQAVD HHHHHHHHHHHHHHH	22.08	-
146	Methylation	AVDKCSYRDVVKMVA HHHHCCHHHHHHHHC	17.60	115386357
155	Phosphorylation	VVKMVADTSEVKLRI HHHHHCCCCCEEEEE	19.63	21712546
156	Phosphorylation	VKMVADTSEVKLRIR HHHHCCCCCEEEEEC	40.72	21712546
252	Phosphorylation	GCRKKCLSILKTLRD CHHHHHHHHHHHHHH	35.03	24719451
280	Phosphorylation	HMKTLVSYECEKHPR CHHEEEEEECCCCCC	19.67	-
289	Phosphorylation	CEKHPRESDWDESCL CCCCCCCCCCCHHHC	45.33	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MB211_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MB211_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MB211_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SIAH1_HUMAN	SIAH1	physical	25416956
UBAC1_HUMAN	UBAC1	physical	26186194
EDRF1_HUMAN	EDRF1	physical	26186194
MEIS1_HUMAN	MEIS1	physical	26186194
MEIS2_HUMAN	MEIS2	physical	26186194
PBX1_HUMAN	PBX1	physical	26186194
PBX2_HUMAN	PBX2	physical	26186194
PBX3_HUMAN	PBX3	physical	26186194
MEIS2_HUMAN	MEIS2	physical	28514442
MEIS1_HUMAN	MEIS1	physical	28514442
PBX2_HUMAN	PBX2	physical	28514442
PBX3_HUMAN	PBX3	physical	28514442
EDRF1_HUMAN	EDRF1	physical	28514442
PBX1_HUMAN	PBX1	physical	28514442
UBAC1_HUMAN	UBAC1	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.