MAX2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MAX2_ARATH
• UniProt AC: Q9SIM9
• Protein Name: F-box protein MAX2 {ECO:0000303|PubMed:11874909}
• Gene Name: MAX2 {ECO:0000303|PubMed:11874909}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 693
• Subcellular Localization: Nucleus .
• Protein Description: Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the senescence. Is necessary for responses to strigolactones and karrikins. Contributes to the selective repression of axillary shoots and moderates the branching by regulating negatively the auxin transport in primary stems, in an AXR1-independent manner. [PubMed: 11487692]
• Protein Sequence: MASTTLSDLPDVILSTISSLVSDSRARNSLSLVSHKFLALERSTRSHLTIRGNARDLSLVPDCFRSISHLDLSFLSPWGHTLLASLPIDHQNLLALRLKFCFPFVESLNVYTRSPSSLELLLPQWPRIRHIKLLRWHQRASQIPTGGDFVPIFEHCGGFLESLDLSNFYHWTEDLPPVLLRYADVAARLTRLDLLTASFTEGYKSSEIVSITKSCPNLKTFRVACTFDPRYFEFVGDETLSAVATSSPKLTLLHMVDTASLANPRAIPGTEAGDSAVTAGTLIEVFSGLPNLEELVLDVGKDVKHSGVALEALNSKCKKLRVLKLGQFQGVCSATEWRRLDGVALCGGLQSLSIKNSGDLTDMGLVAIGRGCCKLTTFEIQGCENVTVDGLRTMVSLRSKTLTDVRISCCKNLDTAASLKAIEPICDRIKRLHIDCVWSGSEDEEVEGRVETSEADHEEEDDGYERSQKRCKYSFEEEHCSTSDVNGFCSEDRVWEKLEYLSLWINVGEFLTPLPMTGLDDCPNLEEIRIKIEGDCRGKRRPAEPEFGLSCLALYPKLSKMQLDCGDTIGFALTAPPMQMDLSLWERFFLTGIGSLSLSELDYWPPQDRDVNQRSLSLPGAGLLQECLTLRKLFIHGTAHEHFMNFLLRIPNLRDVQLRADYYPAPENDMSTEMRVGSCSRFEDQLNSRNIID

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
251	Phosphorylation	ATSSPKLTLLHMVDT HCCCCCEEEEEEECH		24894044
452	Phosphorylation	EVEGRVETSEADHEE EEEEEEECCCCCCCC		30407730
453	Phosphorylation	VEGRVETSEADHEEE EEEEEECCCCCCCCC		30407730

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MAX2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MAX2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MAX2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CUL1_ARATH	CUL1	physical	17346265
SKP1A_ARATH	SKP1	physical	17346265
BZR2_ARATH	BES1	physical	24369836
BZR1_ARATH	BZR1	physical	24369836
BEH2_ARATH	BEH2	physical	24369836
BEH3_ARATH	BEH3	physical	24369836
BEH4_ARATH	BEH4	physical	24369836

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.