LZIC_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LZIC_HUMAN
• UniProt AC: Q8WZA0
• Protein Name: Protein LZIC
• Gene Name: LZIC
• Organism: Homo sapiens (Human).
• Sequence Length: 190
• Protein Sequence: MASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDTDEYEETKKETLEQLSEFNDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLERDLYTQQKVEILTALRKLGEKLTADDEAFLSANAGAILSQFEKVSTDLGSGDKILALASFEVEKTKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
13	Acetylation	KTETSKLKQNLEEQL CHHHHHHHHHHHHHH	40.66	26822725
13	Ubiquitination	KTETSKLKQNLEEQL CHHHHHHHHHHHHHH	40.66	-
47	Ubiquitination	DEYEETKKETLEQLS HHHHHHHHHHHHHHH	64.45	-
61	Ubiquitination	SEFNDSLKKIMSGNM HHCHHHHHHHHCCCC	44.18	-
65	Phosphorylation	DSLKKIMSGNMTLVD HHHHHHHCCCCCHHH	30.41	24043423
69	Phosphorylation	KIMSGNMTLVDELSG HHHCCCCCHHHHHHH	27.85	24043423
75	Phosphorylation	MTLVDELSGMQLAIQ CCHHHHHHHHHHHHH	30.12	24043423
86	Phosphorylation	LAIQAAISQAFKTPE HHHHHHHHHHHCCHH	15.66	24043423
101	Ubiquitination	VIRLFAKKQPGQLRT HHHHHHHCCCCHHHH	59.29	-
131	Ubiquitination	RDLYTQQKVEILTAL HHHHHHHHHHHHHHH	31.83	-
136	Phosphorylation	QQKVEILTALRKLGE HHHHHHHHHHHHHHC	29.34	24719451
162	Phosphorylation	ANAGAILSQFEKVST CCHHHHHHHHHHHHC	27.06	-
166	Ubiquitination	AILSQFEKVSTDLGS HHHHHHHHHHCCCCC	42.65	-
168	Phosphorylation	LSQFEKVSTDLGSGD HHHHHHHHCCCCCCC	27.54	20068231
169	Phosphorylation	SQFEKVSTDLGSGDK HHHHHHHCCCCCCCH	37.93	23312004
173	Phosphorylation	KVSTDLGSGDKILAL HHHCCCCCCCHHEEE	51.63	20068231
182	Phosphorylation	DKILALASFEVEKTK CHHEEEEEEEEECCC	23.84	22617229

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LZIC_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LZIC_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LZIC_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PSF2_HUMAN	GINS2	physical	28514442
CCNC_HUMAN	CCNC	physical	28514442
CDK8_HUMAN	CDK8	physical	28514442
CDK19_HUMAN	CDK19	physical	28514442
SLD5_HUMAN	GINS4	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.