| UniProt ID | LIPR1_HUMAN | |
|---|---|---|
| UniProt AC | P54315 | |
| Protein Name | Inactive pancreatic lipase-related protein 1 | |
| Gene Name | PNLIPRP1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 467 | |
| Subcellular Localization | Secreted . | |
| Protein Description | May function as inhibitor of dietary triglyceride digestion. Lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters (in vitro) (By similarity).. | |
| Protein Sequence | MLIFWTITLFLLGAAKGKEVCYEDLGCFSDTEPWGGTAIRPLKILPWSPEKIGTRFLLYTNENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKKLFEVEEVNCICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEAGSKTPGLSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQMGHLDFFPNGGESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKYYLESILNPDGFAAYPCTSYKSFESDKCFPCPDQGCPQMGHYADKFAGRTSEEQQKFFLNTGEASNFARWRYGVSITLSGRTATGQIKVALFGNKGNTHQYSIFRGILKPGSTHSYEFDAKLDVGTIEKVKFLWNNNVINPTLPKVGATKITVQKGEEKTVYNFCSEDTVREDTLLTLTPC | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 59 | Phosphorylation | IGTRFLLYTNENPNN CCCEEEEEECCCCCC | 15.07 | 24043423 | |
| 60 | Phosphorylation | GTRFLLYTNENPNNF CCEEEEEECCCCCCE | 35.71 | 24043423 | |
| 73 | Phosphorylation | NFQILLLSDPSTIEA CEEEEEECCHHHEEE | 47.66 | 24043423 | |
| 76 | Phosphorylation | ILLLSDPSTIEASNF EEEECCHHHEEECCC | 47.19 | 24043423 | |
| 77 | Phosphorylation | LLLSDPSTIEASNFQ EEECCHHHEEECCCC | 28.38 | 24043423 | |
| 81 | Phosphorylation | DPSTIEASNFQMDRK CHHHEEECCCCCCCC | 25.95 | 24043423 | |
| 384 | Phosphorylation | LFGNKGNTHQYSIFR EECCCCCCCEEEEEE | 21.01 | 22468782 | |
| 388 | Phosphorylation | KGNTHQYSIFRGILK CCCCCEEEEEECCCC | 14.53 | 22468782 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of LIPR1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of LIPR1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of LIPR1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ITA8_HUMAN | ITGA8 | physical | 28514442 | |
| TMEM2_HUMAN | TMEM2 | physical | 28514442 | |
| NPTX1_HUMAN | NPTX1 | physical | 28514442 | |
| T132A_HUMAN | TMEM132A | physical | 28514442 | |
| GPR98_HUMAN | GPR98 | physical | 28514442 | |
| CA2D2_HUMAN | CACNA2D2 | physical | 28514442 | |
| UBR1_HUMAN | UBR1 | physical | 28514442 | |
| UBR2_HUMAN | UBR2 | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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