dbPTM

KIN20_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	KIN20_CAEEL
UniProt AC	Q20471
Protein Name	Casein kinase I isoform delta
Gene Name	kin-20
Organism	Caenorhabditis elegans.
Sequence Length	497
Subcellular Localization	Cytoplasm.
Protein Description	Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity). Is a developmental timer that specifies temporal cell fate selection; acts to control the temporal identity of hypodermal seam cells. Required during late-larval development to prevent adult fates, particularly cell cycle exit and fusion, from being expressed too early..
Protein Sequence	MATMSNDAAAAATWHNNTSTPMDTTEPATNSHNPGETAVIGGPEALLLPSGSGPEEMNRHPLLMAQAHGEHHQPRLLHNFPVIPPPIQQHQQPPLLQQAQPSQIPHPTQPQIDPTMFTQQSGFNWPPIDPNTIAALAQAQLASSHAQFVSLALTLDPTLLSHFLATQQIPPVPQPLVHKKAEMELRVGNRFRLGRKIGSGSFGDIYLGQNIQTNEEVAVKLECVKSKHPQLHIESRLYRIMLGGIGIPEIRWCGQEGDYNVMVMELLGPSLEDLFNFCQRKFSLKTVLLLADQMLSRVEFIHCRDYIHRDIKPDNFLMGLGKRGNLVYIIDFGLAKRYRDSKHQHIAYRENKNLTGTARYASINTHRGIEQSRRDDIESLGYVFMYFNRGTLPWQGLKAVTKRQKYELISEKKISTRVDDLCAGYPEAFAQYLNYCRSLGFEEQPDYGYLRNLFRTLFHRQQFCYDYVFDWNTYKFYNESLEARNNFQQAVPNQRRH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of KIN20_CAEEL !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of KIN20_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of KIN20_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of KIN20_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YP65_CAEEL	B0495.5	physical	14704431
KIN20_CAEEL	kin-20	physical	14704431
BLM_CAEEL	him-6	physical	14704431
ATR_CAEEL	atl-1	physical	14704431
PCNA_CAEEL	pcn-1	physical	14704431

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of KIN20_CAEEL

Related Literatures of Post-Translational Modification