KIF15_MOUSE - dbPTM
KIF15_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID KIF15_MOUSE
UniProt AC Q6P9L6
Protein Name Kinesin-like protein KIF15
Gene Name Kif15
Organism Mus musculus (Mouse).
Sequence Length 1387
Subcellular Localization Cytoplasm. Cytoplasm, cytoskeleton, spindle. Detected during the interphase in the cytoplasm as finely punctuate pattern and irregularly shaped dots. Localizes at the spindle poles and microtubules prior to anaphase. Localizes at the central spindle
Protein Description Plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly..
Protein Sequence MAPGCKSELRNVTNSHSNQPSNEGDAIKVFVRIRPAEEGARSADGEQSFCLSVLSQTTLRLHSNPDPKTFVFDYVAGMDTTQESVFSTVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSDSDNFSHNLRGIIPRSFEYLFSLIDREKEKAGAGKSFLCKCSFIEVYNEQIYDLLDSASVGLYLREHIKKGVFVVGAVEQAVTSAAETYQVLSRGWRNRRVASTSMNRESSRSHAVFTITIESMEKSSETVNIRTSLLNLVDLAGSERQKDTHAEGMRLKEAGNINRSLSCLGQVITALVDVGNGKQRHICYRDSKLTFLLRDSLGGNAKTAIIANVHPGSRCFGETLSTLNFAQRAKLIKNKAVVNEDTQGNVSQLQAEVKRLKEQLSQFTSGQITPESLLARDKEKTNYIEYFLEAMLFFKKSEQEKKSLIEKITQLEDLTLKKEKFIQSNKMIVKFREDQIMRLERLHKEGRGSFLPEEQDRLLSELRDEVQTLREHVEHHPRLAKYAMENHSLREENRRLKLLAPVKRAHEIDAQSIARLEKAFAEVSSTETNDKGLQGFSPKALKESSFFTNTEKLKAQLLQIQTELNNSKQEYEEFKELTRKKQLELESELQSLQKANLNLENLLEATKVCKRQEVSQLNKLHAETLKIITTPTKAYQLCSRLVPKSSPEVGSFGFLCTESSSRLDNDILNEPVPPEMSEQALEAVSEELRTVQEQLSVLQVKLDEEERKNLKLQQNVDKLEHHSTQMQELFSSERSDWTKQQQEHVTQLSDLEKQLQDAQTKNEFLKCEVHDLRIVLNSADKELSLVKLEYSTFKENHEKELSQLSERHVQVQLQLDNARLENEKLLESQACLQDSYDNLQEVMKFEIDQLSKNLQNCKQENETLKSDLHNLVELFEAEKERNNKLSLQFEEDKENSSKEILKVLETVRQEKQKEMAKCEKQMAKIQKLEESLLATENVISSLEKSRESDKELVTNLMNQIQELRISIGEKSETIATLKQELQDINCKYNASLADKEESKELIRRQEVDILELKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQSAQEELTRKEALIQELQHKLNQEKEEVEQKKNEFSLKMRQLEHVMGSATEYPQSPKTPPHFQAHLAKLLETQEQEIEDGRASKTSLQHLVTKLNEDREVKNAEILRMKDQLCEMENLRLESQQLREKNWLLQRQLDDVKRQQESGDQSHPDSQQLKNEHEEIIKERLAKNKLIEEMLKMKTNLEEVQSALHSKEKACHRMSEEIERTRTLESRAFQEKEQLRSKLEEMYEERERTFLEMEMLKKQLEFLAEENGKLVGHQNLHQKIQYVVRLKKENIRLTEETEKLRAENLFLKEKKKEF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
291PhosphorylationEAGNINRSLSCLGQV
HCCCCHHHHHHHHHH		21.8326745281
293PhosphorylationGNINRSLSCLGQVIT
CCCHHHHHHHHHHHH		14.4526745281
300PhosphorylationSCLGQVITALVDVGN
HHHHHHHHHHHCCCC		18.3225338131
373PhosphorylationKAVVNEDTQGNVSQL
CCCCCCCCCCCHHHH		32.00-
395PhosphorylationKEQLSQFTSGQITPE
HHHHHHHHCCCCCHH		25.0621183079
396PhosphorylationEQLSQFTSGQITPES
HHHHHHHCCCCCHHH		29.9528059163
403PhosphorylationSGQITPESLLARDKE
CCCCCHHHHHCCCHH		29.8628059163
440PhosphorylationKSLIEKITQLEDLTL
HHHHHHHHHHHHHHC		37.8620139300
446PhosphorylationITQLEDLTLKKEKFI
HHHHHHHHCCHHHHH		49.1820139300
455PhosphorylationKKEKFIQSNKMIVKF
CHHHHHHCCCEEEEE		33.3330482847
556PhosphorylationKAFAEVSSTETNDKG
HHHHHCCCCCCCCCC		35.1225293948
557PhosphorylationAFAEVSSTETNDKGL
HHHHCCCCCCCCCCC		39.0429895711
559PhosphorylationAEVSSTETNDKGLQG
HHCCCCCCCCCCCCC		49.1325266776
568PhosphorylationDKGLQGFSPKALKES
CCCCCCCCHHHHHHC		32.1126824392
602PhosphorylationLNNSKQEYEEFKELT
HHCCHHHHHHHHHHH		20.4730482847
661PhosphorylationETLKIITTPTKAYQL
HHHHHCCCCCHHHHH		20.6722006019
676PhosphorylationCSRLVPKSSPEVGSF
HHHCCCCCCCCCCCE		45.0925266776
677PhosphorylationSRLVPKSSPEVGSFG
HHCCCCCCCCCCCEE		31.0725266776
833PhosphorylationENHEKELSQLSERHV
HHHHHHHHHHHHHHH		30.1130635358
836PhosphorylationEKELSQLSERHVQVQ
HHHHHHHHHHHHHHH		25.5830635358
859PhosphorylationENEKLLESQACLQDS
HCHHHHHHHHHHHHC		24.0522802335
867PhosphorylationQACLQDSYDNLQEVM
HHHHHHCCCCHHHHH		19.6922802335
976PhosphorylationVISSLEKSRESDKEL
HHHHHHHHHHCHHHH		31.7228059163
1009AcetylationSETIATLKQELQDIN
CHHHHHHHHHHHHCC		37.05-
1022PhosphorylationINCKYNASLADKEES
CCCCCCCCCCCHHHH		22.0622802335
1053PhosphorylationTLRLRILSEDIERDM
HHHHHHCCHHHHHHC		30.7427742792
1134PhosphorylationQLEHVMGSATEYPQS
HHHHHHCCCCCCCCC		17.5828066266
1136PhosphorylationEHVMGSATEYPQSPK
HHHHCCCCCCCCCCC		37.4428066266
1138PhosphorylationVMGSATEYPQSPKTP
HHCCCCCCCCCCCCC		11.3928066266
1141PhosphorylationSATEYPQSPKTPPHF
CCCCCCCCCCCCHHH		24.7024453211
1144PhosphorylationEYPQSPKTPPHFQAH
CCCCCCCCCHHHHHH		45.4928507225
1169PhosphorylationEIEDGRASKTSLQHL
HHHCCCCCHHHHHHH		34.80-
1280AcetylationVQSALHSKEKACHRM
HHHHHHHHHHHHHHH		53.1123236377
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of KIF15_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of KIF15_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of KIF15_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TAF1A_HUMANTAF1Aphysical
26496610
CROCC_HUMANCROCCphysical
26496610
KBP_HUMANKIAA1279physical
26496610
BEGIN_HUMANBEGAINphysical
26496610
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of KIF15_MOUSE

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Related Literatures of Post-Translational Modification

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