| UniProt ID | KCNF1_HUMAN | |
|---|---|---|
| UniProt AC | Q9H3M0 | |
| Protein Name | Potassium voltage-gated channel subfamily F member 1 | |
| Gene Name | KCNF1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 494 | |
| Subcellular Localization |
Membrane Multi-pass membrane protein. |
|
| Protein Description | Putative voltage-gated potassium channel.. | |
| Protein Sequence | MDGSGERSLPEPGSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAAKHELELMELNSSSGGEGKTGGSRSDLDNLPPEPAGKEAPSCSSRLKLSHSDTFIPLLTEEKHHRTRLQSCK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 37 | Phosphorylation | GGVRQVLYGDLLSQY CCHHHHHHHHHHHHC | 15.11 | - | |
| 373 | Phosphorylation | ITMTTVGYGDIYPKT HHHHCCCCCCCCCCC | 13.80 | 18083107 | |
| 377 | Phosphorylation | TVGYGDIYPKTTLGK CCCCCCCCCCCHHHH | 11.92 | 22817900 | |
| 442 | Phosphorylation | SSGGEGKTGGSRSDL CCCCCCCCCCCHHHH | 58.60 | 28348404 | |
| 445 | Phosphorylation | GEGKTGGSRSDLDNL CCCCCCCCHHHHHCC | 29.92 | 28348404 | |
| 447 | Phosphorylation | GKTGGSRSDLDNLPP CCCCCCHHHHHCCCC | 44.19 | 28348404 | |
| 471 | Phosphorylation | CSSRLKLSHSDTFIP CCCCCCCCCCCCCHH | 21.25 | 28348404 | |
| 473 | Phosphorylation | SRLKLSHSDTFIPLL CCCCCCCCCCCHHHH | 34.66 | 28348404 | |
| 475 | Phosphorylation | LKLSHSDTFIPLLTE CCCCCCCCCHHHHCC | 26.86 | 28348404 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of KCNF1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of KCNF1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of KCNF1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| KCNG3_HUMAN | KCNG3 | physical | 12060745 | |
| KCNH1_HUMAN | KCNH1 | physical | 12060745 | |
| KCNV2_HUMAN | KCNV2 | physical | 12060745 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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