ILEUA_MOUSE - dbPTM
ILEUA_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ILEUA_MOUSE
UniProt AC Q9D154
Protein Name Leukocyte elastase inhibitor A
Gene Name Serpinb1a
Organism Mus musculus (Mouse).
Sequence Length 379
Subcellular Localization Cytoplasm.
Protein Description Regulates the activity of the neutrophil proteases and thus, forms complexes with chymotrypsin, elastase, cathepsin G and proteinase-3..
Protein Sequence MEQLSSANTLFALELFQTLNESSPTGNIFFSPFSISSALAMVILGAKGSTAAQLSKTFHFDSVEDIHSRFQSLNAEVSKRGASHTLKLANRLYGEKTYNFLPEYLASTQKMYGADLAPVDFLHASEDARKEINQWVKGQTEGKIPELLSVGVVDSMTKLVLVNAIYFKGMWEEKFMTEDTTDAPFRLSKKDTKTVKMMYQKKKFPFGYISDLKCKVLEMPYQGGELSMVILLPKDIEDESTGLKKIEKQITLEKLLEWTKRENLEFIDVHVKLPRFKIEESYTLNSNLGRLGVQDLFSSSKADLSGMSGSRDLFISKIVHKSFVEVNEEGTEAAAATGGIATFCMLLPEEEFTVDHPFIFFIRHNPTSNVLFLGRVCSP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
34PhosphorylationNIFFSPFSISSALAM
CCEECCCCHHHHHHH		25.58-
56AcetylationSTAAQLSKTFHFDSV
CHHHHHHHHCCCCCH		64.9022826441
62PhosphorylationSKTFHFDSVEDIHSR
HHHCCCCCHHHHHHH		26.8526824392
79UbiquitinationSLNAEVSKRGASHTL
HHCHHHHHCCHHHHH		61.0922790023
79AcetylationSLNAEVSKRGASHTL
HHCHHHHHCCHHHHH		61.0922826441
93PhosphorylationLKLANRLYGEKTYNF
HHHHHHHHCCCCCCC		21.72-
96AcetylationANRLYGEKTYNFLPE
HHHHHCCCCCCCHHH		52.53-
194PhosphorylationLSKKDTKTVKMMYQK
CCCCCCCHHHHHHHC		27.70-
244AcetylationEDESTGLKKIEKQIT
CCCCCCHHHHHHHHH		53.727744545
248AcetylationTGLKKIEKQITLEKL
CCHHHHHHHHHHHHH		50.9323864654
254AcetylationEKQITLEKLLEWTKR
HHHHHHHHHHHHHHH		62.5823864654
260AcetylationEKLLEWTKRENLEFI
HHHHHHHHHHCCEEE		59.8123864654
277AcetylationHVKLPRFKIEESYTL
EEECCCCEEEEEEEC		50.9522826441
277UbiquitinationHVKLPRFKIEESYTL
EEECCCCEEEEEEEC		50.9522790023
298PhosphorylationLGVQDLFSSSKADLS
CCHHHHHHCCCHHHC		40.7929472430
299PhosphorylationGVQDLFSSSKADLSG
CHHHHHHCCCHHHCC		28.6429472430
300PhosphorylationVQDLFSSSKADLSGM
HHHHHHCCCHHHCCC		30.5727180971
301UbiquitinationQDLFSSSKADLSGMS
HHHHHCCCHHHCCCC		48.1122790023
317UbiquitinationSRDLFISKIVHKSFV
CHHHHHEEHHHHHHE		43.8822790023
378PhosphorylationLFLGRVCSP------
EEEEEECCC------		30.6826745281
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ILEUA_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ILEUA_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ILEUA_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ELNE_HUMANELANEphysical
12189154
PRTN3_HUMANPRTN3physical
12189154
CELA1_PIGCELA1physical
12189154
CELA1_BOVINCELA1physical
12189154
CATG_HUMANCTSGphysical
12189154
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ILEUA_MOUSE

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Related Literatures of Post-Translational Modification

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