UniProt ID | ICR5_ARATH | |
---|---|---|
UniProt AC | Q8VYU8 | |
Protein Name | Interactor of constitutive active ROPs 5 | |
Gene Name | ICR5 | |
Organism | Arabidopsis thaliana (Mouse-ear cress). | |
Sequence Length | 396 | |
Subcellular Localization | Cell membrane . Cytoplasm, cytoskeleton . In xylem cells, preferentially colocalizes with cortical microtubules located beneath the secondary wall pits (PubMed:20619818). May be associated to the plasma membrane through the interaction with ARAC10 (P | |
Protein Description | ROP effector binding specifically activated ROPs and linking them to the microtubule cytoskeleton. Involved in ROP-regulated polar growth. Involved in local disassembly of cortical microtubules when associated with ARAC10 and KIN13A and conversely mediates also the elimination of ARAC10 from the plasma membrane by the cortical microtubules. Accumulates at the plus end of shrinking microtubules. Targets KIN13A to microtubules.. | |
Protein Sequence | MQTPKSRPGSLELPQKKSPLPAPKVVRRLKPSGAESDPKTKTISKTQIPKVVADRRSARIPLNEIQKKRTGRIPELESTISQLQEELKKAKEELNRSEALKREAQEEAEDAKHQLMDINASEDSRIEELRKLSQERDKTWQSELEAMQRQHGMDSTALSSAINEVQKLKSKLFESESELEQSKYEVRSLEKLVRQLEEERVNSRDSSSSMEVEELKEAMNLSRQEITQLKSAVEAAETRYQEEYIQSTLQIRSAYEQTEAVKSRYSQREAELTEELNRTKDEIEGLRKELMEKVKEDESTGDLKKLESDLMEVRGSLMDKEMELQILRSAMEKKVETANTEAMEAELKRVKIQCEQWRKAAETAASILNNDEERTDSIETSKMLKKFGVLLKKNHK | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
---|---|---|---|---|---|---|
Oops, there are no PTM records of ICR5_ARATH !! |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ICR5_ARATH !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ICR5_ARATH !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ICR5_ARATH !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
U2A2A_ARATH | ATU2AF65A | physical | 21798944 | |
RAC10_ARATH | RAC10 | physical | 21798944 | |
RAC4_ARATH | ROP2 | physical | 20832900 | |
KN13A_ARATH | KINESIN-13A | physical | 20832900 | |
ICR5_ARATH | RIP4 | physical | 20832900 | |
RAC10_ARATH | RAC10 | physical | 22984069 |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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