ICE1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ICE1_HUMAN
• UniProt AC: Q9Y2F5
• Protein Name: Little elongation complex subunit 1
• Gene Name: ICE1
• Organism: Homo sapiens (Human).
• Sequence Length: 2266
• Subcellular Localization: Nucleus . Nucleus, Cajal body . Colocalizes with COIL in subnuclear Cajal and histone locus bodies. Associates to transcriptionally active chromatin at snRNA genes.
• Protein Description: Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. [PubMed: 22195968]
• Protein Sequence: MMPGETHSAAPGTAADLSRCQGCASLQQNLNEYVEALITLKQKIINTDNLLTEYQKKCDELQFARRENSNLHHQVEEMLQKISPLQKCQEELGSLKAELEEKKSSLKLYQDTHQEYARVKEECLKSDAQKKKLEAKVKKLQEAAVKQTQDFKQLRNEKKILEKEFKKTQERLDEFSKQKNEKELRHIGTQISSDSYGSIDKRKVKLLLKELWLCVNTTHRLPGEGSRCVPEKPAKAITSSRVPGEDGTLPPTQGSPLRTSNVQTCLTKLSMEIKEDFLCQNVEKQSSSGTNCSSDHVFNENGNLEVLVQSHRDGGSTEFVDHDHFFDEDLQAAIDFFKLPPPLLSPVPSPPPMSSPHPGSLPSSFAPETYFGEYTDSSDNDSVQLRNSAECVSEDDTTESQNYFGSLRKNKGSGTWEEKPKSHEAIQALNTWEVNKVTTSGLETFTATLRESSATHSLVGEKHWTTASRSMSDRKRDILHETKTQMEVREMDKSVQTEKTIHKLTRGLCIERLSASPAQEKEAAPGKSELCSSPLGKRPLNELMESEGKTVLSKMMGSPKSEFTKWTRINEITSEPDRITVSGHFHRLSRELEKEKEDTQGFTLGESPESEDDDSGDGMDVAGLDIETSFSSSSTLVALSVGSNPQSSSGLDCGNDTDITTKVFSTEPHHSEHKLQTKTLNTLHLQSEPPECSIGGNNLENSLCALSPELGASNFNDQKSSGIEYTKVVKGLTKIHSLPRSVFMKATKDGQCESQDPRIELTLNKPDFTSLIGSQAALIKSGLGFVKSTSWHHSDLLRKGGEESLRAKSEHEQKTSHQLQKAMPFLQNRGPTPKPDLLRENNNPVEFKTTASVLPNQVSVITKQTRPEKVQSAKLEHLRPHRVEPTLVTENSGNKTGMSTVAKCDGERDDTTQNITEVAAVKSISPEVSASRRKLDFNSPGGSSPVENSDCSTNSRLSFSPENILIQNQDIVREAAVQGDGQKQRQPQATDLDSSGTHGSEMLPATEVTVSGGFSVEETSCGDTGRSGGEALAVANDSTSTPQNANGLWKLKSTTPGGALPECFGTTDTTFSSAFCRKHGETQDTSQSSLPGTLHCYTGIREGGDDTEVESEAFSCSEGSEQQDAPDDSQKNLGDTDAAVAEVRPSLEVGYLTSALQDFNISTFSELDRLSTSEVVMFLESCQLGDYSSGDSVSECSSKGTLSKEMNKELKASEIGEKYRKQPCEEETLGTCEEWIESEEDDYSLKNTSQLTQCSLETLSEVLTKIRQELQTNSEDCNGKDTGSLLLLNVNNNMTTENLKEKSPFRETTGSSSHASEPTPQAAALDTEGSSPISGMPQNENPQSRPEARSDAGRQTDGGEEDLPEPVEPSALCSDSVMEPSIEQSSNCEAETTFQCQIATVTSEVINVLINKDQNLVIEKGDNWTIISGVAVLPHVDQVTLCDIPGDIPISQDQGELEAGCIPVTSAEKSPEASHTGPAFQEAPCGNNLSCPQEDVSSSGQSTNFDKSRLRNRPVKPSIWISSQIYDQNFETQIVASDHTYYNSKLEPSGKNKNRSKISNKDQSNKPVKTSASSRVETHQSEVAQSFSGEKANTKTQRSQTQTILANADTSTPTDCSPDTLSKIRQEVGPPLPPLLAPLIATPPRTSQPLSPLISSSSPSSPASPVGQVSPFRETPVPPAMSPWPEDPRRASPPDPSPSPSAASASERVVPSPLQFCAATPKHALPVPGRLPPCASGHAAVGGPQENSVKILDTMYPELSARARTLNILKGNIQLTRGPPADCKNLPGPASAMIGFKTITSAATAFVKTGSSSGGDCNQDKSRDLGTQQDSSGKRTLSTSTLRSAKRLRLDTGSPEPETRGVTAEGIHKNLPGNLPPAEVATTNEERSCSSPAVSAVSQLPLSPKETVESHDKAIANALKKIAEFSFDLLPVIRSHVYVGNISKKPVMRDQEKEVVYEFSTTKKHLAECLLHSILSELKIQKISMDHNYIHALCRVYVGICRQLGDLERARLFCYSLLKEDFPESEKLTLFIANMWHDIFLSQSVINKAMQLVARQRAKGEVLNCLRAFLNWEKNAPVDVGFMVSKLLLTIQLCPKTEFQPSEKFGEDLSDNTWEYIFAIDLLCCHQKWIWTHDNIISKELWPVMDKWIKYRKGHANIAYTPDIIIASILRLIGRLGQLGLKEGFPSAVKNISSVIGMFIQHAHDEDIPWGIQLAAVYALCDLSPSNPAEISKILEAWRREASKSVPSAIVSCLEEVSALSTEELG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
43	Ubiquitination	ALITLKQKIINTDNL HHHHHHHHHHCCCCH		29967540
47	Phosphorylation	LKQKIINTDNLLTEY HHHHHHCCCCHHHHH		20068231
56	Ubiquitination	NLLTEYQKKCDELQF CHHHHHHHHHHHHHH		29967540
57	Ubiquitination	LLTEYQKKCDELQFA HHHHHHHHHHHHHHH		29967540
83	Phosphorylation	EEMLQKISPLQKCQE HHHHHHHCHHHHHHH		24719451
107	Ubiquitination	EEKKSSLKLYQDTHQ HHHHHHHHHHHHHHH		29967540
116	Phosphorylation	YQDTHQEYARVKEEC HHHHHHHHHHHHHHH		25884760
152	Ubiquitination	VKQTQDFKQLRNEKK HHHHHHHHHHHHHHH		29967540
163	Ubiquitination	NEKKILEKEFKKTQE HHHHHHHHHHHHHHH		29967540
177	Ubiquitination	ERLDEFSKQKNEKEL HHHHHHHHHHCHHHH		29967540
196	Phosphorylation	TQISSDSYGSIDKRK CCCCCCCCCCCCHHH		28555341
198	Phosphorylation	ISSDSYGSIDKRKVK CCCCCCCCCCHHHHH		28555341
201	Ubiquitination	DSYGSIDKRKVKLLL CCCCCCCHHHHHHHH		29967540
238	Phosphorylation	EKPAKAITSSRVPGE CCCCCCEECCCCCCC		26074081
239	Phosphorylation	KPAKAITSSRVPGED CCCCCEECCCCCCCC		26074081
240	Phosphorylation	PAKAITSSRVPGEDG CCCCEECCCCCCCCC		26074081
248	Phosphorylation	RVPGEDGTLPPTQGS CCCCCCCCCCCCCCC		29255136
252	Phosphorylation	EDGTLPPTQGSPLRT CCCCCCCCCCCCCCC		23401153
255	Phosphorylation	TLPPTQGSPLRTSNV CCCCCCCCCCCCCCH		30266825
259	Phosphorylation	TQGSPLRTSNVQTCL CCCCCCCCCCHHHHH		27174698
260	Phosphorylation	QGSPLRTSNVQTCLT CCCCCCCCCHHHHHH		27174698
264	Phosphorylation	LRTSNVQTCLTKLSM CCCCCHHHHHHHHHH		27174698
267	Phosphorylation	SNVQTCLTKLSMEIK CCHHHHHHHHHHHHH		27174698
345	Phosphorylation	KLPPPLLSPVPSPPP CCCCCCCCCCCCCCC		26074081
349	Phosphorylation	PLLSPVPSPPPMSSP CCCCCCCCCCCCCCC		26074081
354	Phosphorylation	VPSPPPMSSPHPGSL CCCCCCCCCCCCCCC		26074081
355	Phosphorylation	PSPPPMSSPHPGSLP CCCCCCCCCCCCCCC		26074081
360	Phosphorylation	MSSPHPGSLPSSFAP CCCCCCCCCCCCCCC		26074081
363	Phosphorylation	PHPGSLPSSFAPETY CCCCCCCCCCCCCCC		26074081
364	Phosphorylation	HPGSLPSSFAPETYF CCCCCCCCCCCCCCC		26074081
388	Phosphorylation	DSVQLRNSAECVSED CCEEEECCCEECCCC		23312004
393	Phosphorylation	RNSAECVSEDDTTES ECCCEECCCCCCCCC		25849741
397	Phosphorylation	ECVSEDDTTESQNYF EECCCCCCCCCHHHH		30108239
398	Phosphorylation	CVSEDDTTESQNYFG ECCCCCCCCCHHHHH		30108239
400	Phosphorylation	SEDDTTESQNYFGSL CCCCCCCCHHHHHCC		30108239
403	Phosphorylation	DTTESQNYFGSLRKN CCCCCHHHHHCCCCC		30108239
406	Phosphorylation	ESQNYFGSLRKNKGS CCHHHHHCCCCCCCC		30108239
438	Phosphorylation	TWEVNKVTTSGLETF CEECCEEECCCHHEE		20068231
439	Phosphorylation	WEVNKVTTSGLETFT EECCEEECCCHHEEE		30177828
440	Phosphorylation	EVNKVTTSGLETFTA ECCEEECCCHHEEEE		30177828
444	Phosphorylation	VTTSGLETFTATLRE EECCCHHEEEEEHHH		20068231
446	Phosphorylation	TSGLETFTATLRESS CCCHHEEEEEHHHCC		20068231
448	Phosphorylation	GLETFTATLRESSAT CHHEEEEEHHHCCCC		30177828
452	Phosphorylation	FTATLRESSATHSLV EEEEHHHCCCCCCCC		30377224
453	Phosphorylation	TATLRESSATHSLVG EEEHHHCCCCCCCCC		30377224
455	Phosphorylation	TLRESSATHSLVGEK EHHHCCCCCCCCCCE		25627689
457	Phosphorylation	RESSATHSLVGEKHW HHCCCCCCCCCCEEC		25159151
462	Acetylation	THSLVGEKHWTTASR CCCCCCCEECCCCCC		26051181
483	Ubiquitination	RDILHETKTQMEVRE HHHHHHHHHHHHHHH		29967540
484	Phosphorylation	DILHETKTQMEVREM HHHHHHHHHHHHHHH		-
505	Phosphorylation	EKTIHKLTRGLCIER HHHHHHHHHHHHHHH		-
514	Phosphorylation	GLCIERLSASPAQEK HHHHHHHCCCHHHHH		25159151
516	Phosphorylation	CIERLSASPAQEKEA HHHHHCCCHHHHHHC		29255136
521	Ubiquitination	SASPAQEKEAAPGKS CCCHHHHHHCCCCCC		-
528	Phosphorylation	KEAAPGKSELCSSPL HHCCCCCCHHCCCCC		24732914
532	Phosphorylation	PGKSELCSSPLGKRP CCCCHHCCCCCCCCC		25463755
533	Phosphorylation	GKSELCSSPLGKRPL CCCHHCCCCCCCCCH		22167270
546	Phosphorylation	PLNELMESEGKTVLS CHHHHHHHCCHHHHH		25159151
553	Phosphorylation	SEGKTVLSKMMGSPK HCCHHHHHHHHCCCH		-
558	Phosphorylation	VLSKMMGSPKSEFTK HHHHHHCCCHHHHCC		26074081
561	Phosphorylation	KMMGSPKSEFTKWTR HHHCCCHHHHCCCEE		26074081
564	Phosphorylation	GSPKSEFTKWTRINE CCCHHHHCCCEEHHH		26074081
567	Phosphorylation	KSEFTKWTRINEITS HHHHCCCEEHHHCCC		-
574	Phosphorylation	TRINEITSEPDRITV EEHHHCCCCCCEEEE		28555341
580	Phosphorylation	TSEPDRITVSGHFHR CCCCCEEEEHHHHHH		27251275
582	Phosphorylation	EPDRITVSGHFHRLS CCCEEEEHHHHHHHH		20873877
589	Phosphorylation	SGHFHRLSRELEKEK HHHHHHHHHHHHHHH		29523821
671	Phosphorylation	FSTEPHHSEHKLQTK ECCCCCCCCCCCCCC		28555341
674	Ubiquitination	EPHHSEHKLQTKTLN CCCCCCCCCCCCEEC		29967540
702	Phosphorylation	GGNNLENSLCALSPE CCCCCCCCCCHHCHH		22210691
707	Phosphorylation	ENSLCALSPELGASN CCCCCHHCHHHCCCC		25159151
727	Ubiquitination	SSGIEYTKVVKGLTK CCCCCHHHHHHCHHH		29967540
733	Phosphorylation	TKVVKGLTKIHSLPR HHHHHCHHHHHCCCH		-
734	Ubiquitination	KVVKGLTKIHSLPRS HHHHCHHHHHCCCHH		29967540
737	Phosphorylation	KGLTKIHSLPRSVFM HCHHHHHCCCHHHHH		20860994
745	Ubiquitination	LPRSVFMKATKDGQC CCHHHHHHHCCCCCC		-
765	Acetylation	RIELTLNKPDFTSLI CEEEEECCCCHHHHH		23236377
765	Ubiquitination	RIELTLNKPDFTSLI CEEEEECCCCHHHHH		29967540
787	Ubiquitination	KSGLGFVKSTSWHHS HHCCCCCCCCCCCHH		29967540
790	Phosphorylation	LGFVKSTSWHHSDLL CCCCCCCCCCHHHHH		28555341
832	Phosphorylation	FLQNRGPTPKPDLLR HHHHCCCCCCCCHHH		23898821
834	Ubiquitination	QNRGPTPKPDLLREN HHCCCCCCCCHHHCC		29967540
859	Phosphorylation	SVLPNQVSVITKQTR HHCCCCEEEEECCCC		28555341
874	Ubiquitination	PEKVQSAKLEHLRPH CHHHHHCCCHHCCCC		29967540
889	Phosphorylation	RVEPTLVTENSGNKT CCCCEEEECCCCCCC		27134283
892	Phosphorylation	PTLVTENSGNKTGMS CEEEECCCCCCCEEE		21815630
923	Phosphorylation	TEVAAVKSISPEVSA HHHHHHHCCCHHHCH		30266825
925	Phosphorylation	VAAVKSISPEVSASR HHHHHCCCHHHCHHH		29255136
929	Phosphorylation	KSISPEVSASRRKLD HCCCHHHCHHHCCCC		22167270
931	Phosphorylation	ISPEVSASRRKLDFN CCHHHCHHHCCCCCC		22167270
934	Ubiquitination	EVSASRRKLDFNSPG HHCHHHCCCCCCCCC		29967540
939	Phosphorylation	RRKLDFNSPGGSSPV HCCCCCCCCCCCCCC		30266825
943	Phosphorylation	DFNSPGGSSPVENSD CCCCCCCCCCCCCCC		30266825
944	Phosphorylation	FNSPGGSSPVENSDC CCCCCCCCCCCCCCC		30266825
949	Phosphorylation	GSSPVENSDCSTNSR CCCCCCCCCCCCCCC		28450419
952	Phosphorylation	PVENSDCSTNSRLSF CCCCCCCCCCCCCCC		22199227
953	Phosphorylation	VENSDCSTNSRLSFS CCCCCCCCCCCCCCC		27251275
958	Phosphorylation	CSTNSRLSFSPENIL CCCCCCCCCCHHHEE		30266825
960	Phosphorylation	TNSRLSFSPENILIQ CCCCCCCCHHHEEEC		29255136
983	Acetylation	AVQGDGQKQRQPQAT HHCCCCCCCCCCCCC		26051181
1040	Phosphorylation	AVANDSTSTPQNANG EEECCCCCCCCCCCC		25627689
1041	Phosphorylation	VANDSTSTPQNANGL EECCCCCCCCCCCCC		21815630
1052	Ubiquitination	ANGLWKLKSTTPGGA CCCCEEEEECCCCCC		29967540
1053	Phosphorylation	NGLWKLKSTTPGGAL CCCEEEEECCCCCCC		25159151
1054	Phosphorylation	GLWKLKSTTPGGALP CCEEEEECCCCCCCC		25627689
1055	Phosphorylation	LWKLKSTTPGGALPE CEEEEECCCCCCCCC		21815630
1078	Ubiquitination	FSSAFCRKHGETQDT CHHHHHHHHCCCCCC		29967540
1085	Phosphorylation	KHGETQDTSQSSLPG HHCCCCCCCCCCCCC		21712546
1086	Phosphorylation	HGETQDTSQSSLPGT HCCCCCCCCCCCCCE		21712546
1088	Phosphorylation	ETQDTSQSSLPGTLH CCCCCCCCCCCCEEE		21712546
1089	Phosphorylation	TQDTSQSSLPGTLHC CCCCCCCCCCCEEEE		30576142
1097	Phosphorylation	LPGTLHCYTGIREGG CCCEEEEECCEECCC		30576142
1098	Phosphorylation	PGTLHCYTGIREGGD CCEEEEECCEECCCC		30576142
1171	Phosphorylation	FSELDRLSTSEVVMF CHHHHCCCHHHHHHH		22468782
1218	Acetylation	KASEIGEKYRKQPCE HHHHHHHHHCCCCCC		19608861
1238	Phosphorylation	TCEEWIESEEDDYSL CHHHHHHCCCCCCCC		22817901
1244	Phosphorylation	ESEEDDYSLKNTSQL HCCCCCCCCCCHHHH		24719451
1248	Phosphorylation	DDYSLKNTSQLTQCS CCCCCCCHHHHHHHH		21712546
1249	Phosphorylation	DYSLKNTSQLTQCSL CCCCCCHHHHHHHHH		21712546
1252	Phosphorylation	LKNTSQLTQCSLETL CCCHHHHHHHHHHHH		27282143
1284	Phosphorylation	CNGKDTGSLLLLNVN CCCCCCCCEEEEECC		28555341
1291	Ubiquitination	SLLLLNVNNNMTTEN CEEEEECCCCCCCCC		24816145
1303	Phosphorylation	TENLKEKSPFRETTG CCCHHHCCCCCCCCC		22210691
1308	Phosphorylation	EKSPFRETTGSSSHA HCCCCCCCCCCCCCC		22210691
1309	Phosphorylation	KSPFRETTGSSSHAS CCCCCCCCCCCCCCC		22210691
1316	Phosphorylation	TGSSSHASEPTPQAA CCCCCCCCCCCCCCC		22210691
1319	Phosphorylation	SSHASEPTPQAAALD CCCCCCCCCCCCCCC		22210691
1327	Phosphorylation	PQAAALDTEGSSPIS CCCCCCCCCCCCCCC		30576142
1330	Phosphorylation	AALDTEGSSPISGMP CCCCCCCCCCCCCCC		30108239
1331	Phosphorylation	ALDTEGSSPISGMPQ CCCCCCCCCCCCCCC		25849741
1334	Phosphorylation	TEGSSPISGMPQNEN CCCCCCCCCCCCCCC		30108239
1344	Phosphorylation	PQNENPQSRPEARSD CCCCCCCCCCCHHCC		22210691
1465	Phosphorylation	EAGCIPVTSAEKSPE EECEEECCCCCCCCC		26074081
1466	Phosphorylation	AGCIPVTSAEKSPEA ECEEECCCCCCCCCC		26074081
1470	Phosphorylation	PVTSAEKSPEASHTG ECCCCCCCCCCCCCC		27050516
1474	Phosphorylation	AEKSPEASHTGPAFQ CCCCCCCCCCCCCCC		25159151
1476	Phosphorylation	KSPEASHTGPAFQEA CCCCCCCCCCCCCCC		25159151
1490	Phosphorylation	APCGNNLSCPQEDVS CCCCCCCCCCHHHHC		30177828
1497	Phosphorylation	SCPQEDVSSSGQSTN CCCHHHHCCCCCCCC		30177828
1561	Ubiquitination	NRSKISNKDQSNKPV CCHHCCCCCCCCCCC		24816145
1571	Phosphorylation	SNKPVKTSASSRVET CCCCCCCCCCHHHHH		28555341
1581	Phosphorylation	SRVETHQSEVAQSFS HHHHHHHHHHHHHHC		30576142
1586	Phosphorylation	HQSEVAQSFSGEKAN HHHHHHHHHCCCCCC		30576142
1588	Phosphorylation	SEVAQSFSGEKANTK HHHHHHHCCCCCCCC		25159151
1591	Acetylation	AQSFSGEKANTKTQR HHHHCCCCCCCCCCC		26051181
1610	Phosphorylation	TILANADTSTPTDCS EHHHCCCCCCCCCCC		25627689
1611	Phosphorylation	ILANADTSTPTDCSP HHHCCCCCCCCCCCH		25627689
1612	Phosphorylation	LANADTSTPTDCSPD HHCCCCCCCCCCCHH		25262027
1614	Phosphorylation	NADTSTPTDCSPDTL CCCCCCCCCCCHHHH		21712546
1617	Phosphorylation	TSTPTDCSPDTLSKI CCCCCCCCHHHHHHH		25262027
1620	Phosphorylation	PTDCSPDTLSKIRQE CCCCCHHHHHHHHHH		25262027
1622	Phosphorylation	DCSPDTLSKIRQEVG CCCHHHHHHHHHHHC		25262027
1623	Acetylation	CSPDTLSKIRQEVGP CCHHHHHHHHHHHCC		26051181
1642	Phosphorylation	LLAPLIATPPRTSQP CCHHHCCCCCCCCCC		28176443
1646	Phosphorylation	LIATPPRTSQPLSPL HCCCCCCCCCCCCCC		30177828
1647	Phosphorylation	IATPPRTSQPLSPLI CCCCCCCCCCCCCCC		28985074
1651	Phosphorylation	PRTSQPLSPLISSSS CCCCCCCCCCCCCCC		28985074
1655	Phosphorylation	QPLSPLISSSSPSSP CCCCCCCCCCCCCCC		30177828
1656	Phosphorylation	PLSPLISSSSPSSPA CCCCCCCCCCCCCCC		30177828
1657	Phosphorylation	LSPLISSSSPSSPAS CCCCCCCCCCCCCCC		30177828
1658	Phosphorylation	SPLISSSSPSSPASP CCCCCCCCCCCCCCC		30177828
1660	Phosphorylation	LISSSSPSSPASPVG CCCCCCCCCCCCCCC		30177828
1661	Phosphorylation	ISSSSPSSPASPVGQ CCCCCCCCCCCCCCC		30177828
1664	Phosphorylation	SSPSSPASPVGQVSP CCCCCCCCCCCCCCC		30177828
1670	Phosphorylation	ASPVGQVSPFRETPV CCCCCCCCCCCCCCC		30177828
1675	Phosphorylation	QVSPFRETPVPPAMS CCCCCCCCCCCCCCC		17081983
1682	Phosphorylation	TPVPPAMSPWPEDPR CCCCCCCCCCCCCCC		17081983
1692	Phosphorylation	PEDPRRASPPDPSPS CCCCCCCCCCCCCCC		29255136
1697	Phosphorylation	RASPPDPSPSPSAAS CCCCCCCCCCCCCCC		30266825
1699	Phosphorylation	SPPDPSPSPSAASAS CCCCCCCCCCCCCHH		30266825
1701	Phosphorylation	PDPSPSPSAASASER CCCCCCCCCCCHHCC		30266825
1704	Phosphorylation	SPSPSAASASERVVP CCCCCCCCHHCCCCC		29255136
1706	Phosphorylation	SPSAASASERVVPSP CCCCCCHHCCCCCCC		29255136
1712	Phosphorylation	ASERVVPSPLQFCAA HHCCCCCCCCHHHCC		30266825
1720	Phosphorylation	PLQFCAATPKHALPV CCHHHCCCCCCCCCC		25159151
1756	Phosphorylation	VKILDTMYPELSARA HHHHHHHCHHHHHHH		24719451
1760	Phosphorylation	DTMYPELSARARTLN HHHCHHHHHHHHHHH		24719451
1789	Ubiquitination	DCKNLPGPASAMIGF CCCCCCCCCHHHCCC		24816145
1791	Phosphorylation	KNLPGPASAMIGFKT CCCCCCCHHHCCCEE		28555341
1809	Phosphorylation	AATAFVKTGSSSGGD CCEEHHHCCCCCCCC		-
1811	Phosphorylation	TAFVKTGSSSGGDCN EEHHHCCCCCCCCCC		28985074
1812	Phosphorylation	AFVKTGSSSGGDCNQ EHHHCCCCCCCCCCC		-
1813	Phosphorylation	FVKTGSSSGGDCNQD HHHCCCCCCCCCCCH		28985074
1822	Phosphorylation	GDCNQDKSRDLGTQQ CCCCCHHCCCCCCCC		20860994
1827	Phosphorylation	DKSRDLGTQQDSSGK HHCCCCCCCCCCCCC		23403867
1831	Phosphorylation	DLGTQQDSSGKRTLS CCCCCCCCCCCEECC		26552605
1832	Phosphorylation	LGTQQDSSGKRTLST CCCCCCCCCCEECCH		23403867
1836	Phosphorylation	QDSSGKRTLSTSTLR CCCCCCEECCHHHHH		23186163
1838	Phosphorylation	SSGKRTLSTSTLRSA CCCCEECCHHHHHHH		22210691
1839	Phosphorylation	SGKRTLSTSTLRSAK CCCEECCHHHHHHHC		22210691
1840	Phosphorylation	GKRTLSTSTLRSAKR CCEECCHHHHHHHCC		25159151
1841	Phosphorylation	KRTLSTSTLRSAKRL CEECCHHHHHHHCCC		23186163
1852	Phosphorylation	AKRLRLDTGSPEPET HCCCCCCCCCCCCCC		30266825
1854	Phosphorylation	RLRLDTGSPEPETRG CCCCCCCCCCCCCCC		19664994
1859	Phosphorylation	TGSPEPETRGVTAEG CCCCCCCCCCCCCCC		30266825
1888	Phosphorylation	ATTNEERSCSSPAVS CCCCCCCCCCCCCCH		30266825
1890	Phosphorylation	TNEERSCSSPAVSAV CCCCCCCCCCCCHHH		30266825
1891	Phosphorylation	NEERSCSSPAVSAVS CCCCCCCCCCCHHHH		25159151
1895	Phosphorylation	SCSSPAVSAVSQLPL CCCCCCCHHHHCCCC		30266825
1898	Phosphorylation	SPAVSAVSQLPLSPK CCCCHHHHCCCCCHH		30266825
1903	Phosphorylation	AVSQLPLSPKETVES HHHCCCCCHHHHHHH		25159151
1907	Phosphorylation	LPLSPKETVESHDKA CCCCHHHHHHHHHHH		30576142
1910	Phosphorylation	SPKETVESHDKAIAN CHHHHHHHHHHHHHH		30576142
1926	Phosphorylation	LKKIAEFSFDLLPVI HHHHHHHCCCHHHHH		-
2015	Phosphorylation	ERARLFCYSLLKEDF HHHHHHHHHHHHHHC		24719451
2016	Phosphorylation	RARLFCYSLLKEDFP HHHHHHHHHHHHHCC		24719451
2059	Ubiquitination	LVARQRAKGEVLNCL HHHHHHHHHHHHHHH		24816145
2147	Acetylation	ELWPVMDKWIKYRKG HHHHHHHHHHHHHCC		130079

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ICE1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ICE1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ICE1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ELL_HUMAN	ELL	physical	21729782
EAF1_HUMAN	EAF1	physical	21729782
ICE2_HUMAN	ICE2	physical	21729782
COIL_HUMAN	COIL	physical	24413172
USPL1_HUMAN	USPL1	physical	24413172

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.