| UniProt ID | HXD12_MOUSE | |
|---|---|---|
| UniProt AC | P23812 | |
| Protein Name | Homeobox protein Hox-D12 | |
| Gene Name | Hoxd12 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 268 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.. | |
| Protein Sequence | MCERSLYRAGYVGSLLNLQSPDSFYFSNLRANGSQLAALPPISYPRSALPWATTPASCTPAQPATASAFGGFSQPYLTGSGPIGLQSPGAKDGPEDQVKFYTPDAPTASEERSRTRPPFAPESSLVHSALKGTKYDYAGVGRTAPGSATLLQGAPCASSFKEDTKGPLNLNMAVQVAGVASCLRSSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVQREQALALY | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 114 | Dimethylation | TASEERSRTRPPFAP CCCHHHHCCCCCCCC | 40.76 | - | |
| 114 | Methylation | TASEERSRTRPPFAP CCCHHHHCCCCCCCC | 40.76 | 18964655 | |
| 240 | Phosphorylation | LSNRLNLSDQQVKIW HHHHCCCCHHHHHHH | 32.09 | 22942356 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HXD12_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HXD12_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HXD12_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| PO6F1_MOUSE | Pou6f1 | physical | 20211142 | |
| RNPS1_MOUSE | Rnps1 | physical | 20211142 | |
| ZN292_MOUSE | Zfp292 | physical | 20211142 | |
| RPB9_MOUSE | Polr2i | physical | 20211142 | |
| TF2AY_MOUSE | Gtf2a1l | physical | 20211142 | |
| TAF13_MOUSE | Taf13 | physical | 20211142 | |
| WWP1_MOUSE | Wwp1 | physical | 20211142 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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