HXD12_MOUSE - dbPTM
HXD12_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HXD12_MOUSE
UniProt AC P23812
Protein Name Homeobox protein Hox-D12
Gene Name Hoxd12
Organism Mus musculus (Mouse).
Sequence Length 268
Subcellular Localization Nucleus.
Protein Description Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis..
Protein Sequence MCERSLYRAGYVGSLLNLQSPDSFYFSNLRANGSQLAALPPISYPRSALPWATTPASCTPAQPATASAFGGFSQPYLTGSGPIGLQSPGAKDGPEDQVKFYTPDAPTASEERSRTRPPFAPESSLVHSALKGTKYDYAGVGRTAPGSATLLQGAPCASSFKEDTKGPLNLNMAVQVAGVASCLRSSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVQREQALALY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
114DimethylationTASEERSRTRPPFAP
CCCHHHHCCCCCCCC
40.76-
114MethylationTASEERSRTRPPFAP
CCCHHHHCCCCCCCC
40.7618964655
240PhosphorylationLSNRLNLSDQQVKIW
HHHHCCCCHHHHHHH
32.0922942356

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of HXD12_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HXD12_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HXD12_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PO6F1_MOUSEPou6f1physical
20211142
RNPS1_MOUSERnps1physical
20211142
ZN292_MOUSEZfp292physical
20211142
RPB9_MOUSEPolr2iphysical
20211142
TF2AY_MOUSEGtf2a1lphysical
20211142
TAF13_MOUSETaf13physical
20211142
WWP1_MOUSEWwp1physical
20211142

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HXD12_MOUSE

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Related Literatures of Post-Translational Modification

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