HUS1B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HUS1B_HUMAN
• UniProt AC: Q8NHY5
• Protein Name: Checkpoint protein HUS1B
• Gene Name: HUS1B
• Organism: Homo sapiens (Human).
• Sequence Length: 278
• Protein Sequence: MKFRAKITGKGCLELFIHVSGTVARLAKVCVLRVRPDSLCFGPAGSGGLHEARLWCEVRQGAFQQFRMEGVSEDLDEIHLELTAEHLSRAARSAAGASSLKLQLTHKRRPSLTVAVELVSSLGRARSVVHDLPVRVLPRRVWRDCLPPSLRASDASIRLPRWRTLRSIVERMANVGSHVLVEANLSGRMTLSIETEVVSIQSYFKNLGNPPQSAVGVPENRDLESMVQVRVDNRKLLQFLEGQQIHPTTALCNIWDNTLLQLVLVQEDVSLQYFIPAL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
22	Phosphorylation	LFIHVSGTVARLAKV EEEECHHHHHHHHEE	11.95	24260401
127	Phosphorylation	SSLGRARSVVHDLPV HHHCCCHHHHHCCCC	27.75	24719451
186	Phosphorylation	VLVEANLSGRMTLSI EEEEEECCCCCEEEE	24.94	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HUS1B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HUS1B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HUS1B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RAD1_HUMAN	RAD1	physical	11944979
RAD1_HUMAN	RAD1	physical	28514442
RAD9A_HUMAN	RAD9A	physical	28514442
ZBT14_HUMAN	ZBTB14	physical	28514442
DNLZ_HUMAN	DNLZ	physical	28514442
PSME3_HUMAN	PSME3	physical	28514442
F192A_HUMAN	FAM192A	physical	28514442
PCDH7_HUMAN	PCDH7	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.