GPDA_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GPDA_HUMAN
• UniProt AC: P21695
• Protein Name: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
• Gene Name: GPD1
• Organism: Homo sapiens (Human).
• Sequence Length: 349
• Subcellular Localization: Cytoplasm.
• Protein Sequence: MASKKVCIVGSGNWGSAIAKIVGGNAAQLAQFDPRVTMWVFEEDIGGKKLTEIINTQHENVKYLPGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHLKANATGISLIKGVDEGPNGLKLISEVIGERLGIPMSVLMGANIASEVADEKFCETTIGCKDPAQGQLLKELMQTPNFRITVVQEVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGPVSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKELLNGQKLQGPETARELYSILQHKGLVDKFPLFMAVYKVCYEGQPVGEFIHCLQNHPEHM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	Phosphorylation	DIGGKKLTEIINTQH CCCCCCHHHHHHCCC	33.74	-
56	Phosphorylation	KLTEIINTQHENVKY CHHHHHHCCCCCCCC	22.39	-
117	Phosphorylation	KANATGISLIKGVDE HCCCCCCEEEECCCC	25.95	24719451
145	Phosphorylation	ERLGIPMSVLMGANI HHHCCCHHHHHCCCC	13.52	30622161
154	Phosphorylation	LMGANIASEVADEKF HHCCCCHHHHCCCCH	28.89	28857561
248	Phosphorylation	LFCSGPVSSATFLES HHHCCCCCHHHHHHH	19.86	24275569
249	Phosphorylation	FCSGPVSSATFLESC HHCCCCCHHHHHHHC	31.40	24275569
251	Phosphorylation	SGPVSSATFLESCGV CCCCCHHHHHHHCCH	30.60	27251275
289	Succinylation	KSIEQLEKELLNGQK CCHHHHHHHHHCCCC	63.35	-
289	Succinylation	KSIEQLEKELLNGQK CCHHHHHHHHHCCCC	63.35	-
326	Phosphorylation	FPLFMAVYKVCYEGQ HHHHHHHHHHHHCCC	6.54	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GPDA_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GPDA_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GPDA_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PTN_HUMAN	PTN	physical	16169070
GNA1_HUMAN	GNPNAT1	physical	26344197
GPD1L_HUMAN	GPD1L	physical	28514442
IDH3B_HUMAN	IDH3B	physical	28514442
NMD3_HUMAN	NMD3	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.