dbPTM

GIT1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GIT1_SCHPO
UniProt AC	Q9P7K5
Protein Name	Adenylate cyclase activation protein git1
Gene Name	git1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	1098
Subcellular Localization	Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Septum.
Protein Description	Involved in the glucose/cAMP-signaling pathway. Required for maintaining basal cAMP levels and for producing a glucose-triggered cAMP response..
Protein Sequence	MGFTSVEPPDFFDWTARAIFLLSTLRSRRNAKQIERENALLDQIKELLSIAIIQCHERNIPSIDLPPSFFNYVCEQLPRHPFAKIASSYIDTHTLFFQISISSFLCRFSNCSEDEIRLFKQHQSLDSFLLSLFDLLCSHHFSVEFTSISLIIKSSQWLFYTLSDYAHESLTGVEADITTKFLSTLADTWPEFEEQCTLSKHLFLLGDFSLISYVKVLCGVFNIPNYNAFILSVEDLLPENISFAAVADFQLSKYRAINDNSVLRSDDFSSKAVFDKYVERECYYSENAISKIFQNYPDLAVLFEELQYAEGNNDLLSAILNTNKYTLRPDDCAPYFYRLMDLCLRYCYSQSNEIGTNVLWSMTTSFINIWRIHPGTCCCVVLSIYWPYLEDKLLKFSDLGDIFEYFFSLIHDCDYAIWSVHDEHQFSELLAFYHRRALNDLVEELGSCPRSSDSCRAILDILNNYIFSCPLFLVTPEELEEQYTDFFKKLKEKYGEFFQNLLKKELTGKPESDLEGLRLVGVQLQATYENLKSNFSARIFNQLSVHSFFAEATCHLFLEKLPTITKTYVYSNCKEIPDHILEMINALYQQTRALVACTGYLSSDYPKIYEAFSGTFVYRNLSLIIDKGLANVLQTVLRESFIPKRSRFYSDSTKMILAPLQDCYDFLQKIDWPSSKDANRFYLHLGKLSENYIHYYVDSMYALFIYSTDIPLKAEPLVPDLPVKQLKEKASHFKRHSGDPNFLKLYRESFTLINTVSLVSGWLKMLHQRIDYKILTEKVMHFKDMEVPSATVIISIKMAHLLVTPKAPYSFSVLLQDPESEFCVHTRDVYDELVPNWKETYQMEITNVKRFKLIIYQRNIHTGLETVYGHATLEVDPDKLKQGHGKDVWLDITNKGQILIGLRVLLKRETPNYYCFAQMEYLTVTEVKMLNVLMISLSKFIRNSLRNSGLMDFVRYLDGDENDNAEAETKEKMDELQARCEKEQQSLLAELDDFFYWIYVNLLPKPLFYLLSRLWFGLLETFRDILVPPVTDSTLRRIPLNKRELKMVYSWLQLFYDFFRNFQDIAPFDFLNTDEYKSVMAIKDYYFVKSKDVKRVSS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of GIT1_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GIT1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GIT1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GIT1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KAPB_SCHPO	pka1	genetic	16143612
CYAA_SCHPO	cyr1	physical	16489217
PYP1_SCHPO	pyp1	genetic	8832414
CYAA_SCHPO	cyr1	genetic	1849107

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GIT1_SCHPO

Related Literatures of Post-Translational Modification