GGN_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GGN_MOUSE
• UniProt AC: Q80WJ1
• Protein Name: Gametogenetin
• Gene Name: Ggn
• Organism: Mus musculus (Mouse).
• Sequence Length: 673
• Subcellular Localization: Isoform 1: Cytoplasm, perinuclear region. Localizes along the nuclear membrane.; Isoform 2: Cytoplasmic vesicle.; Isoform 3: Nucleus, nucleolus.
• Protein Description: May be involved in spermatogenesis..
• Protein Sequence: MGNVQSEPSAGGGSRKEQASDRASDSRRTPLVEPEVTPSSPAMRLARGLGVWFPGSSGPPGLLIPPEPQASSSPLPLTLELPSPVTPPPEEAAAVSTPPPPPVGTLLPAPSKWRKPTGTSVPRIRGLLEASHRGQGDPPSLRPLPPLPRQLTEKDPVLRAPAPPPTPLEPRKQLPPAPSTCDPQPLSRRITLASSATSPTESQVRHSSEGQAAGGAHGGVPPQAGEGEMARSATSESGLSLLCKVTFKSGPHLSPTSASGPLAAKASPGAGGGGLFASSGAISYAEVLKQGPQPPGATRPLGEVPPGATRPLGEVPRAAQETEGGDGDGEGCSGPPSVPAPLARALPPPPYTTFPGSKPKFDWVSPPDGTERHFRFNGAVGGIGAPRRRTTTLSGPWGSPPPRSGQTHPSSGPRRPTPALLAPPMFIFPAPNNGEPVRPVPPSPQQIPPLPPPPPTPPATPPPAPPPTPQPPALPRTPILVARPPTPGPGHLESALAPTPPSTLSPTAAADQVPAATPATVTSQVPATATAELSPPMPQPKTRTRRNKGPRAARGVIREEGTSGDGPREPNTAPVTDSSSGGGGGGSNGTSTAGASNKGTARHWPPFEVLNSCPCKCYCRHQRRHRRLPRNVSAWLSTPTNHLSEPPWVATVKLAGSLVAGLEHYDLQATHST

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
37	Phosphorylation	PLVEPEVTPSSPAMR CCCCCCCCCCCHHHH	18.78	25293948
39	Phosphorylation	VEPEVTPSSPAMRLA CCCCCCCCCHHHHHH	39.32	25293948
40	Phosphorylation	EPEVTPSSPAMRLAR CCCCCCCCHHHHHHC	20.20	25293948
254	Phosphorylation	FKSGPHLSPTSASGP ECCCCCCCCCCCCCC	24.09	25293948
256	Phosphorylation	SGPHLSPTSASGPLA CCCCCCCCCCCCCCC	33.28	25293948
257	Phosphorylation	GPHLSPTSASGPLAA CCCCCCCCCCCCCCC	24.66	25293948
267	Phosphorylation	GPLAAKASPGAGGGG CCCCCCCCCCCCCCC	24.14	25293948
399	Phosphorylation	TLSGPWGSPPPRSGQ CCCCCCCCCCCCCCC	30.30	25159016

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GGN_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GGN_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GGN_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FANCL_MOUSE	Fancl	physical	12574169
GGN_MOUSE	Ggn	physical	12574169
FANCL_MOUSE	Fancl	physical	23451117
FACD2_MOUSE	Fancd2	physical	23451117
BRCC3_MOUSE	Brcc3	physical	23451117

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.